NIH awards new $14.5 million, five-year grant to the Scripps Research Institute
... only where scientists have overcome the technical challenge of producing and purifying the membranes. The Trouble with Membrane Proteins The main problem with using conventional techniques in structural biology to solve membrane proteins is simple and twofold-- membrane proteins are hard to produce and ...College students recognized & rewarded for their innovative work
...hnology, and creative invention. This prestigious challenge recognizes and rewards the innovations, discoveries, and research by college and university students and their advisors for projects leading to inventions that can be patented. Introduced by the National Inventors Hall of Fame in 1990, the Collegiat...An embryonic stem cell model for Parkinson's disease
... the neurodegeneration remain unknown. Part of the challenge is finding a model that can adequately mimic the loss of dopamine cells. In two papers published in PLoS Biology , Asa Abeliovich and colleagues make the case that a model based on mouse embryonic stem cells offers a promising platform for dissectin...Experts present new research on hot topics in aging at GSA's annual meeting in Washington, DC
...nced for the long term. In order to respond to the challenge of the baby boom and later beneficiaries, the long-term financing gap needs to be closed. This symposium offers further discussion of Social Security reforms and their potential impact on the future program and its beneficiaries by presenting results...US Agency for International Development awards $34 million to Virginia Tech
...chers are identifying and addressing problems that challenge the day-to-day lives of people in every corner of the world," said Steger. "And through our strong partnerships with other universities and government and non-government organizations, as well as with individual families and farmers, we are putting k...Emory chemists develop bacteria that may help decaffeinate coffee
...own to bind to theophylline tightly. The remaining challenge was to couple this binding to a vital function of the bacteria -- the production of a protein. To do this, the Emory team created a new sequence of RNA known as a "riboswitch." In bacteria, riboswitches normally recognize essential molecules, such a...Researchers provide road map for generating B cells from stem cells
...want to generate," Singh added. "This is the next challenge facing the field. Molecular biologists are used to manipulating single genes, but this may require controlling several components in an ordered manner to properly direct a stem cell through a given developmental sequence."...Where in the brain decisions are made
...are specifically involved in making decisions, the challenge has been to develop rigorous laboratory behavioral experiments that could pinpoint those areas. Now, Paul Glimcher and colleague Michael Dorris have used a game-playing approach to demonstrate that a region of the cortex called the lateral intraparie...NHGRI seeks next generation of sequencing technologies
...ond set, seven groups will take on the longer-term challenge of developing revolutionary technologies to realize the vision of sequencing a human genome for $1,000 or less. The approaches pursued by both sets of grants have many complementary elements that integrate biochemistry, chemistry and physics with eng...Surgeon General's report underscores the importance of new thinking on bone health
...tive effort to improve bone health. "The greatest challenge always has been to drive home the importance of osteoporosis prevention. For decades, too many people have not adequately considered the repercussions of their diets and lifestyles on their bone health. We believe today's report is an important tool ...Study identifies target for preventing sexual transmission of HIV
...sufficient to protect rhesus macaques from vaginal challenge with a virus like HIV. A natural immune messenger (chemokine) called RANTES can bind to CCR5 and by binding, forces the cell to internalize the CCR5 receptor so HIV cannot bind to it. We developed an altered RANTES molecule, called PSC-RANTES, that ...To save dolphin's dorsal fin experts combine medical technology and teamwork
...eney, V.M.D., Dolphin Quest co-presidents. A major challenge the team faced was keeping the application in place on the active dolphin in a saltwater lagoon environment for the time it was expected to take for the soft tissue to sufficiently regenerate. The medical team employed a specially designed sling cust...Predicting infection risk of mosquito-borne disease
...vid Smith, Jonathan Dushoff, and F. Ellis McKenzie challenge this assumption. Using a mathematical model, the authors show that the rate at which humans are bitten and the proportion of infectious mosquitoes peak at different times and places, revealing that the standard metric of estimating the risk of infect...Trojan-horse therapy blocks buildup of Alzheimer's plaque
...The new "Trojan horse" technique overcomes a major challenge in drug design namely, the limited ability of molecules small enough to enter a cell to interfere with interactions between much larger proteins. The researchers said it might also be possible to use this new approach to sabotage proteins central to...Darwin's greatest challenge tackled: the mystery of eye evolution
... Laboratory (EMBL) have now tackled Darwin's major challenge in an evolutionary study published this week in the journal Science. They have elucidated the evolutionary origin of the human eye. Researchers in the laboratories of Detlev Arendt and Jochen Wittbrodt have discovered that the light-sensitive cells o...Powerful 'toolkit' developed for functional profiling of yeast genes
..." says Boeke. "So we can mix the mutants together, challenge them to survive removal of a particular gene, nurture the ones that make it and use microarrays to see quickly which ones are missing." The researchers dubbed the combined technique dSLAM, for diploid-based synthetic lethality analysis on micro...Declining fish supply linked to wildlife consumption in West Africa, Science study reports
...conservation and poverty elimination. "The larger challenge is to allow human society to meet its potential and share the fruits of economic growth while sustaining a biosphere that not only sustains full ecological functions, but which retains its living diversity," the "Review" authors write....2004 IUCN Red List of Threatened Species reveals 15,589 species at risk of extinction
...and the Ethiopian Highlands). A major conservation challenge will therefore be to reconcile the demands of large numbers of people on the environment, while protecting the biodiversity upon which so many people's livelihoods depend. The importance of international support in safeguarding biodiversity is highli...Tiny plant a model for commercially important trees
...es are required for a plant to produce wood is the challenge we face," Beers said. Graduate student Chengsong Zhao measured the genes expressed in wood isolated from Arabidopsis using technology available at the Virginia Bioinformatics Institute at Virginia Tech. The technology is capable of measuring ex...Tips from the Journals of the American Society for Microbiology
... Piette. 2004. Postprocessing in vitro digestion challenge to evaluate survival of Escherichia coli O157:H7 in fermented dry sausages. Applied and Environmental Microbiology, 70. 11: 6637-6642.) *************************************** Shock Therapy Effective Against Bacteria on Stainless Steel Implants E...