Every moment counts: Predicting treatment responses earlier for brain tumor patients
...I, it is often difficult to tell tumor growth from changes caused by treatment (such as radiation). In additi...id Chen. "We used molecular imaging to measure the changes of metabolism in tumor cells," and FLT-PET provided much higher response rates than MRI, she explain...Genomic signatures identify targeted therapies for lung cancer
...sing genes, called oncogenes, set off a cascade of changes in the activity of hundreds of other interacting genes -- either increasing or decreasing their activity. Rather than looking at each of these oncogenes individually, this new method presents a more global view by identifying the pathway encompassi...NIAID supports research into etiology of fungal-induced inflammation in chronic sinusitis
... and sinuses and leads to the inflammatory mucosal changes characteristic of CS. Dr. Jens Ponikau, Assistant Professor of Clinical Otolaryngology, University at Buffalo, commented: Research supported by the National Institutes of Health had previously shown that CS patients have an exaggerated immune respo...JCI table of contents -- June 1, 2007
...her thrombin contributes to longer-term structural changes in the arterial wall that promote narrowing and clotting. In the June 1 issue of the Journal of Clinical Investigation, Toshio Matsumoto and colleagues from The University of Tokushima Graduate School of Health Biosciences, Japan, argue that it can. ...Cigarette smoke alters DNA in sperm, genetic damage could pass to offspring
...s have demonstrated in mice that smoking can cause changes in the DNA sequence of sperm cells, alterations th...inherited, these mutations persist as irreversible changes in the genetic composition of off-spring. said Carole Yauk, Ph.D., lead author of the study and rese...Cold Spring Harbor Protocols features methods to understand embryos, clones, stem cells
...ts to observe and test morphological and molecular changes that occur in a normally opaque embryo, and to see whats happening several layers deep into the embryo. The protocol is freely available at http://www.cshprotocols.org/cgi/content/full/2007/12/pdb.prot4749 ....Small-scale agricultural changes may help eradicate widespread disease
COLUMBUS, Ohio Small changes in agricultural and sanitation practices may eliminate the spread of a disease that affects some 200 million people living in developing nations around the world. Researchers working in remote farming villages in western China report that providing......cols designed to maximise fish survival via subtle changes to management practices. Owing to bag limits, legal sizes and non-consumptive angling, between 30 and 50% of the total recreational catch is released each year in Australia. This amounts to more than 47 million fish being caught and released annual...Researchers discover inherited mutation for leukemia
... geneticists have come to believe that such subtle changes are common causes of cancer, and this is one of the first, strong examples of that principle." The study succeeded because it combined the field of gene mutation research and the new field of epigenetics, which identifies genes silenced by faulty ...Manchester researcher wins Libyan award
...se single nucleotide polymorphisms (SNP) may cause changes in the amino acid sequence of important proteins. Methods sensitive to single base-pair mutations for the fast screening of patient samples to identify disease-causing mutations will be essential in their diagnosis, prevention and treatment. Professo...'Virtual Patient' to simulate real-time organ motions for radiation therapy
...to accurately predict and monitor these anatomical changes to provide the most effective treatment possible at any given time," Xu said. The fourth dimension of the VIP-Man is not easily achieved, according to Xu. Currently Xu and De are focusing their energy on respiratory function. "Using advanced comput...Molecular motors may speed nutrient processing
...e composition of the microvillar surface to handle changes in "what comes down the pipe;" and that it serves a role in cell-cell communication by launching vesicles that contain signaling proteins. Tyska and his team also plan to explore whether myosin-1a is serving a similar membrane-moving role in its othe...How E. coli evolves to adapt to changing acidity
...his advantage allows scientists to investigate how changes occur and how they affect an organism's individual physiology and overall community." In the July/August 2007 issue, the first of three issues that will contain articles from the collection, Bradley S. Hughes, Alistair J. Cullum, and Albert F. Ben...Yin and yang -- Balance could play key role in progression of Alzheimer's disease
...hen that delicate balance is changed, pathological changes will occur in the brain and the persons memories become hazy, leading to eventual dementia." Wang expects that this imbalance could be the main factor in the progression of Alzheimers disease. If correct, the addition of AB40 may stop the diseases...Natural compound and exercise boost memory in mice
...picatechin also promoted structural and functional changes in the dentate gyrus, a part of the brain involved in the formation of learning and memory. The findings, published in the May 30 issue of The Journal of Neuroscience , suggest that a diet rich in flavonols may help reduce the incidence or severity ...Climate change signal detected in the Indian Ocean
...analysing climate simulations we can see there are changes in features of the ocean that cannot be explained ...SIRO oceanographer Dr Gael Alory. "These oceanic changes are almost certainly linked to changes in the heat structure of the atmosphere and have led to a ris...ACS News Service Weekly PressPac -- May 23, 2007
...e changes, which involved a loss of CL followed by changes in the remaining CL, occurred as early as 5 days a... cells in the pancreas. Researchers observed the changes in two models of diabetes commonly used to study the two types of human diabetes. The changes happen...New mouse model closely mimics human cancers
... years, compared the patterns of these chromosomal changes in the mice with patterns observed in more than 40...erations that in many cases were identical to such changes in human tumors. This match up, said the researchers, suggested that the new mouse model may be usef...Alcohol use during pregnancy leads to greater risk of extreme preterm delivery
...sible, yet if I had to guess, I think we would see changes in the same direction." The bottom line, said Sokol, is that there is a substantial risk of extreme preterm delivery that is associated with alcohol use during pregnancy. "It would be best for women to just not drink during pregnancy," he said....Endogenous cannabinoids linked to fetal brain damage imposed by maternal cannabis use
...vide new perspectives to identifying the molecular changes in the brains of individuals prenatally affected by maternal cannabis abuse", says Dr. Tibor Harkany who has led the studies. "This is of social impact given the continuous growing use of marijuana, the most common illicit drug, in our society." Earl...