Other highlights in the Aug. 7 JNCI
...Wilms Tumor Is Specific to IGF2 Gene Epigenetic changes in Wilms tumor, a rare type of childhood kidney cancer, do not appear to be widespread. The most common epigenetic change in Wilms tumor is the loss of imprinting of the IGF2 gene. In this case, loss of imprinting means the copy of IGF2 that you g...In limiting life span, study finds booming bacteria innocent
...the elderly. To explore the consequences of such changes in bacteria with age in greater detail, the researchers looked to flies. Drosophila flies are emerging as an ideal model system in which to study most aspects of immunity, including innate immune pathwayswhich represent the bodys first line of defens......ertification, salinisation, water degradation, and changes in climate due to altered water flows from land to...vin Ramankutty (McGill University) likens land use changes to fuel emissions in their potential to drive climatic changes. According to Ramankutty, local land ...Gene variant is associated with brain anatomy, clinical course of ADHD
...speech areas. While our current study demonstrates changes in cortical thickness and symptoms occurring in tandem, a future goal is to refine further our appreciation of cortical thickness by examining the links between this neuroanatomical variable and putative cognitive endophenotypes [invisible but measur...Genetic analysis finds greater threat in frog-killing fungus
...volved together. However, biologists theorize that changes to the environment - from global warming to pollution from agricultural chemicals - could make native frog populations susceptible to a pathogen with which they've previously co-existed. According to the study, neither epidemic spread nor endemism ...See what you're spewing as you speed along
... measure the variation in gas concentration during changes in the operating conditions of a Rover engine, such as increasing and decreasing the throttle, adjusting the air to fuel ratio, and start-up. This is the first instance of this type of near-IR diode laser sensor being used directly in the exhaust o...Why nectar-feeding bats need a 'power drink' to fly
... knife edge, these bats are very vulnerable to any changes in their environment that interrupt their fuel supply for even a short period. Working with a captive breeding colony in Germany, Dr Christian Voigt of the Leibniz Institute for Zoo and Wildlife Research in Berlin and Professor John Speakman of the...Improved NIST SRM aids lead poisoning detection
...assurance for lead blood measurements. Significant changes in material composition, lead levels and expanded uncertainties of the certified lead concentrations make SRM 955c an even more effective tool for use in addressing lead poisoning, a condition particularly harmful to the developing nervous systems of...How cells change the pace of their steps
...orrelate the mechanical forces related to chemical changes occurring within cells, said Firtel. This study will help us understand the basis of a number of human genetics diseases and developmental abnormalities....National Ecological Observatory Network featured at ESA/SER Joint International Conference
...rch platform for discovering and understanding how changes in climate, land use, and invasive species impact ...m data on ecological responses of the biosphere to changes in land use and climate, and on feedbacks with the geosphere, hydrosphere, and atmosphere. NEON is...Immunity in social amoeba suggests ancient beginnings
... to form a slug that can move. Eventually the slug changes to produce cells that perform specific functions spores and stalks. In this new report, Dr. Adam Kuspa, chair of biochemistry and molecular biology at BCM, and his colleagues describe a new kind of cell they dubbed a sentinel cell. Sentinel cells...UC experts detail new standard for cleaner transportation fuels
...oals. Stabilizing the climate will require major changes in the coming years, and the new fuels that will come on the market in response to the low carbon fuel standard will be an important part of that change, said Farrell. One of the key roles for the state agencies will be ensuring that the competition...New survey documents the headaches of computerized medicine
...ies were the generation of new kinds of errors and changes in the hospital power structure which fewer than half of the respondents ranked as high in importance. All eight categories identified in an extensive preliminary study at five hospitals of varying sizes were encountered by most of the hospitals su...Unlocking proteins from their cellular shell
... in tissue. Penn researchers used force to induce changes in the structures of cytoskeletal proteins and, em... the rigidification of breast tumors often reflect changes in protein organization and assembly that adversely affect static and dynamic forces in, on, and aro...Synchrotron could help save the Tassie devil
...otron to see if the disease causes any biochemical changes in the devils which could be detected in their hai...sed on Australian research showing disease-related changes in the composition of human hair. The suggestion is that similar changes could occur in Tasmanian de...JCI table of contents: August 1, 2007
...iated by an inability of the neurons to respond to changes in glucose levels and not caused by impaired responses to the hormone regulators of energy balance leptin and insulin. These latter observations, that AMPK is only required for the response of POMC and AgRP neurons to some signals that regulate energ...New data reveal pregnancies exposed to accutane despite risk management program
... the report and will carefully review any proposed changes to the program following the meeting tomorrow of the FDAs Dermatologic and Ophthalmic Drugs Advisory Committee and Drug Safety and Risk Management Advisory Committee. Its certainly a positive step that FDA and the drug manufacturers have made this ...Rare example of Darwinism seen in action
.... The researchers found that the biggest genetic changes were in those species of the minnows that had developed placentas, supporting the Darwinian theory of natural selection. The study also provides independent support for the theory of conflict between the male and female genetic material in produci...Huntington's disease study shows animal models on target
...lable models accurately recapitulate the molecular changes observed in human HD, explains Luthi-Carter. It underlines the suitability of these animal models for preclinical testing of drugs that affect gene transcription in Huntingtons Disease. ...Negative effects of plastic's additive blocked by nutrient supplements
...earch known as epigenetics, a name which refers to changes happening over and above the gene sequence without...d in the production of plastics, caused noticeable changes in the offspring without altering any of the offsprings genes. Additionally, the researchers discove...