Fat may affect electrical impulses in brain, heart
...c Chemistry and Molecular Pharmacology. Potassium channels are among the most important cell channels used for propagating electrical signals in nerve and heart muscle. Their protein units form pores th...Protein tags regulate key ion channel
...channel function: reversible peptide linkage." Ion channels are in every cell in the human body. They are tigh...s, separating the cell from the outside world. Ion channels allow ions such as potassium, sodium and calcium to flow in and out and so are key regulators of man...Yale researchers use laser light to remote control flies
...e study, explained that the photoreceptors are ion channels that spark action potentials when illuminated. Depending on which neurons are light-sensitive, the remote-controlled flies jump, fly or change their walking patterns on command. "The ability to control brain functions non-invasively opens many new po...At the molecular level, the predator is the prey
...e newts' skin, can bind to garter snake nerve cell channels and prevent sodium ions from flowing freely. "These channels are absolutely fundamental to every aspect of nerve and muscle function and are highly specific gate...Paralytic shellfish toxins cause mutation that allows clams to accumulate 100 times more toxin
... that prevents them from binding to the sodium ion channels in the clam's nerve tissue. Instead of binding to the ion channels and causing paralysis and later death, the toxins build up in the clam, accumulating about 100 times...VCU research shows Viagra prevents anti-cancer drug induced heart damage
...eatment with DOX by opening the mitochondrial KATP channels in cardiac cells," said Kukreja. Mitochondria are cellular organelles critical for converting oxygen into ATP, the key fuel for cellular function. According to Kukreja, free radicals generated in the mitochondria of cardiac cells by DOX lead to the b...14 highlighted physiology papers from IUPS 2005: From 'genomics to functions'
...a. "NMDA receptor regulation by mitochondrial KATP channels and adenosine receptors in cortical neurons of the anoxia-tolerant western painted turtle." Physiology 381.3. Leslie T. Buck, Damian Shin and Matthew Pamenter. University of Toronto Zoology Department. Featured topic: Buck is also participating in "...Statins, other cholesterol depletors, may disrupt hypertension development: UCSD study
... looking at the expression and localization of ion channels into caveolae that may further explain the increased calcium intake into cell."...In anoxia, why can't humans be more like western painted turtles?
...n: "NMDA receptor regulation by mitochondrial KATP channels and adenosine receptors in cortical neurons of the...e of investigation is to see whether the potassium channels may be part of an oxygen sensing mechanism, which some believe. "Our ultimate goal is to determine t...Sea skate experiment sheds light on human cell transport
...and glucose can't be moved between cells. And when channels are blocked, damaged cells can't die. This cell "s...a possible relationship between operation of these channels and the uncontrolled multiplication of cancer cells," Goldstein said. "If so, this research points u...HHMI taps two Long Island researchers as among the nation's most promising scientists
...ory system; the structure and function of cellular channels critical to the heart and other muscles; the identification of genes regulating organ development and programmed cell death; and processes fundamental to learning and memory....Oceans more vulnerable to agricultural runoff than previously thought, study finds
...water from irrigation runs off through streams and channels into the estuaries and then out to sea." Matson and her colleagues wondered if each fertilization and irrigation event would trigger a noticeable phytoplankton bloom near the mouth of the Yaqui River, which is located on the mainland side of the gulf...APS announces 2005 Young Investigators Awards
...ological function and regulating mechanisms of ion channels in kidney cells. Dr. Ma also studies pathological relevance of the ion channels in certain kidney diseases, such as diabetic and polycystic kidney disease. David L. Allen, Ph.D. ...Molecular thermometers on skin cells detect heat and camphor
...o the brain. The most obvious evidence is that TRP channels are activated by thermal heat within a particular ...s of 33 C (91.5 F) and above. Similarly, other TRP channels are specifically activated within hot, warm, cool, or cold temperature ranges. Most of these tempera...Muon opportunists: Detecting the unseen with natural probes
...ntists can measure its shape and look for interior channels where molten rock may be rising, an early sign of a potential eruption. The research team has studied several volcanoes in Japan, including as assessment of the amount of molten rock within the crater of Mt. Asama. Closer to home, scientists at Los ...Open microfluidic and nanofluidic systems
...in general but only if the geometry of the surface channels is carefully matched with their wettability (PNAS ...sed on open and, thus, directly accessible surface channels which can be fabricated on solid substrates using available photolithographic methods. The simplest ...Research identifies promising route for treating age-related hearing loss
...uorescent dye that only moves through the membrane channels of functional hair cells. In further studies, Chen and his colleagues found that knocking out the Rb1 gene in cultured mature inner ear cells from mice triggered the cells to begin proliferating. "This experiment demonstrated that it was a direct e...Development of portable infectious disease detector
... and the use of fluids flowing through microscopic channels to move and manipulate small numbers of cells reliably. In the process, the group has applied for more than 12 patents. Meanwhile, Pria has developed a micro-optical fluorescence spectroscopy system and used it as the basis for a inexpensive male fer...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
...the huge numbers of potential species and reaction channels makes things very difficult." Computer simulations can be powerful tools in contemporary molecular biology research, aiding scientists in analyzing data and in testing hypotheses with simulated outcomes before testing them experimentally. The predict...Pinatubo's rivers show the danger isn't over when volcanic eruption ends
...tays," Montgomery said. Eventually, all the river channels will stabilize and lahars will occur infrequently, Gran said. That's because the fine-grained ash and pumice typically are the first to be carried away by water. As a river cuts deeper into the sediment, coarser material eventually will form a more s...