Tag: "channels" at biology news
Study implicates potassium channel mutations in neurodegeneration and mental retardation
... codes for one of the proteins that form potassium channels
pore-like openings in the cell membrane that cont...ave found abnormalities in the number of potassium channels
in Parkinson's, Alzheimer's, and Huntington's diseases. Together with the new study, these findings...
Mechanism for memory revealed in neurons of electric fish
... by turning on special cell membrane channels. The channels
give the fish neurons the ability to retain a memo...utation that neurons do," says Zakon. "We have ion channels
[in the neurons] and we know those are activated. The mystery is how a short stimulus leads to such ...
VCU study shows Levitra may protect the heart
...age of the heart by opening the mitochondrial KATP channels
in cardiac cells. Mitochondria are cellular organelles critical for converting oxygen into ATP, the key fuel for cellular function. "This study provides important information about the mechanism by which the PDE-5 inhibitors work. Furthermore, it is...
JCI table of contents, February 9, 2006
...inhibitor of normal ROMK in kidney cells. The ROMK channels
from Cftr-deficient mice also demonstrated an impa... PKA-regulated ATP sensitivity of Kir1.1 potassium channels
in mouse kidney AUTHOR CONTACT: Steven C. Hebert Yale University School of Medicine, New Haven, Con...
How sperm crack the whip
...atSper1 block fertilization in mice. And since the channels
in human sperm are very similar, there's no reason to believe you couldn't develop a male or female birth control pill that would block the protein before it functions to hyperactivate sperm, preventing fertilization," he said....
Capturing the electrical activity of sperm
...ity will also allow the researchers to study other channels
that regulate sperm behavior. For example, the sperm head also contains calcium channels
whose identity and functions are unknown. The channels
may help the sperm release enzymes that disso...
Stable polymer nanotubes may have a biotech future
...T nanotubes may have biotechnology applications as channels
for tiny volumes of chemicals in nanofluidic reactor devices, for example, or as the "world's smallest hypodermic needles" for injecting molecules one at a time. Carbon nanotubes are of keen interest in nanotechnology research, especially for making ...
Gene variation increases SIDS risk in African Americans
...ade no difference. Cells with the normal or Y1103 channels
"were found to function indistinguishably," the au...re acidic environment, the cells with the abnormal channels
began to misbehave. In normal cells, these sodium channels
are closed at rest. In response to ele...
Molecular force field helps cancer cells defend against attack
..., or VEGFR-3. The protein is tied to the growth of channels
in the lymph system that serve as cellular superhighways for cancer spread and is found in breast, colon and thyroid tumors. Cance and colleagues were the first to pull FAK out of human tumors and to show that human cancers make the molecule in large...
Secrets of the sea yield stronger artificial bone
...are expelled from the forming ice and entrapped in channels
between the ice crystals. The result is a layered structure that roughly resembles nacre's wafer-like construction. The Berkeley Lab team believed this same freezing process could be used to cast an exquisitely layered material that comes close to mi...
Cardiovascular and immunology research alliance announced by Yale and Boehringer Ingelheim
... line blood vessels, the identification of calcium channels
in cells that mediate immunity, the protection of kidney blood vessels from hypertension, and the therapeutic potential of the regulatory protein HIF-1a in the cardiovascular system. Both the projects and the funding will be flexible and have two ph...
Master genetic switch found for chronic pain
...nerve cells was impaired. The animals had lost ion channels
known to be involved in reacting to painful heat o...ranscriptional control program for many of the ion channels
and receptors known to transduce noxious stimuli has intriguing implications for the design of more ...
Academy honors 15 for major contributions to science
...rphology and dynamics of natural and managed river channels
at a range of scales." The prize was established by a bequest of Emily B. Warren in memory of her father and has been presented since 1969. Also to be honored at the April 23 ceremony is NORMAN R. AUGUSTINE, retired chairman and CEO, Lockheed Martin...
Protein 'nanosprings' most resilient found in nature
...sduction. Ankyrin proteins also coordinate the ion channels
and transporters that control the beating of the heart. In 2004, Bennett's team linked mutations in the gene ankyrin-B to an inherited cardiac arrhythmia syndrome that can lead to sudden death ( http://www.dukemednews.org/news/article.php?id=9389 ). ...
Machinery of the 'marijuana munchies'
...he endocannabinoid effects by inhibiting pore-like channels
in the neurons that regulate the flow of calcium into the neurons. Such calcium is necessary for the synthesis of endocannabinoids. In further studies of mice genetically altered to be leptin deficient, the researchers found the DSI to be more prolon...
Aquaporin and obesity
...ommon to human obesity and the evaluation of these channels
as a possible means for therapeutic treatment. Pioneering team The Multidisciplinary Team of diagnosis and treatment of obesity is a project begun in 1999. Later, the Hospital aided in the creation of the Metabolic Research Laboratory of the Un...
Membrane research opens window to benefits for plants, humans
... conserved in them. "Plant cells close their water channels
in response to drought stress in order to preserve... the structural difference between open and closed channels
is telling. When open, the protein allows water to go through; when closed, its pore size is reduced...
Sahara's edge studied from ground, air and space to improve water management
...superior in geometric resolution and the number of channels
or polarisations to the capability of presently orbiting satellites - will also be used to anticipate the performance and usefulness of future satellite sensors. Aquifer and TIGER The Aquifer Project has in addition to SASS a second working area,...
New technique helps researchers determine amino-acid charge
...acking. All cells have membrane proteins that form channels
to allow water and/or ions to pass through. Malfunctions have been linked to such problems as hypertension, abnormal insulin secretion, abnormal heart conditions and brain seizures. As a result, these membrane proteins are often targeted by drug trea...
Leibniz Prize winners 2006
...ning the interactions between the various membrane channels
and neurotransmitters involved in these communication processes and to representing the sequence in which this communication takes place. His work is related to the research conducted by Nobel Prize laureate Erwin Neher, and it has advanced progress ...
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