Tag: "chronic" at biology news

Power-boosting signal in muscle declines with age

... Those properties can most likely be attributed to chronic activation of the AMPK pathway. "In regards to i...ed acute exposure to an AMPK-stimulating chemical, chronic exposure through feeding of another chemical that induces AMPK by mimicking an energy shortage, and ...

Risk of preterm birth appears to vary by season

...ce the risk of cerebral palsy, mental retardation, chronic lung disease, and vision and hearing loss, as well as other developmental problems. Researchers analyzed data from 75,399 deliveries over a 10-year period at the university-affiliated Magee-Womens Hospital of UPMC, grouping each by season of "last ...

New analyses reinforce efficacy of Remicade in treatment of severe psoriasis

...is, particularly those patients burdened with this chronic disease who previously failed phototherapy or syst...e is affecting the nails, a difficult-to-treat and chronic manifestation that can affect a large proportion of patients with psoriasis," said Phoebe Rich, MD, ...

Remicade therapy shown to improve productivity in patients treated for chronic plaque psoriasis

...yses offer further insight into the impact of this chronic inflammatory disease on patient productivity and t... of psoriasis have been compared to those of other chronic illnesses such as rheumatoid arthritis, hypertension, heart disease, diabetes and depression. Skin ...

Adult stem cells to repair hearts damaged by severe coronary artery disease investigated

...ve symptoms and clinical outcomes in subjects with chronic myocardial ischemia (CMI), a severe form of corona...of new people each year. A person who suffers from chronic myocardial ischemia continues to experience insufficient flow of oxygen-rich blood to the heart desp...

Scientists see DNA get 'sunburned' for the first time

...es sunburn its sting. Scientists also believe that chronic damage creates mutations that lead to diseases such as skin cancer. For this study, the chemists used a technique called transient absorption to observe the DNA damage. Transient absorption is based on the idea that molecules absorb light at specif...

MU researchers to study how changes in infrastructure affect physical activity behavior

...activity is vital in the prevention of obesity and chronic diseases such as diabetes and heart disease, but o...ty, the impact of those changes on obesity-related chronic disease at the national level could significantly reduce the burden on our health care system," Saye...

News tips from the Journal of Neuroscience

...urrent I A was upregulated, an effect mimicked by chronic pharmacological block of cac channels, apparently attributable to upregulation of Shaker (Sh) potassium channels. 3. Roll, Pitch, and Yaw, Lamprey-Style Pavel V. Zelenin, Grigori N. Orlovsky, and Tatiana G. Deliagina Steering a lamprey through...

Marshfield Clinic's electronic health record first to receive CCHIT certification

...poorly controlled diabetes, hypertension and other chronic conditions in order to test EHR functions such as potential adverse drug reactions, disease management and treatment plans. ...

Nicotine: The link between cigarette smoking and kidney disease progression?

...ke (CS) is the most preventable cause of death and chronic disease in the United States. In addition to being...which cigarette smoke may accelerate some types of chronic kidney disease are currently unknown. A new study, being published by the American Physiological Soc...

Carbon monoxide protects mice from multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory disorder that causes degeneration of the nerves in the brain and spinal cord, leading to various symptoms including muscle weakness and pain. Most individuals with MS go through cycles of disease and remission, leading to the suggestion ...

Molecular link between inflammation and cancer discovered

... growth and development gone awry, can result from chronic inflammation, which is an out-of-control response ...er. "Although there is plenty of evidence that chronic inflammation can promote cancer, the cause of this relationship is not understood," said Alexander H...

JCI table of contents: January 25, 2006

...multiple sclerosis Multiple sclerosis (MS) is a chronic inflammatory disorder that causes degeneration of the nerves in the brain and spinal cord, leading to various symptoms including muscle weakness and pain. Most individuals with MS go through cycles of disease and remission, leading to the suggestion ...

Complex channels

...on channels are likely to be involved in epilepsy, chronic pain, neurodegenerative diseases and muscular diseases, and ion channels are the target of many drugs. Understanding the basic biological phenomena behind the way proteins organize themselves and orchestrate biological processes may allow scientists ...

Scripps Research study reveals new activation mechanism for pain sensing channel

...pharmaceutical companies as a potential target for chronic pain, Patapoutian noted....

New test predicts blood cancer's sensitivity to experimental cancer drug

...oy the cancer. The researchers demonstrated that chronic lymphocytic leukemia, CLL, which is diagnosed in 10,000 Americans each year, is an easy mark for the new drug because the cancerous cells are strongly dependent on a particular survival molecule, Bcl-2, that keeps the self-destruct signals at bay. Th...

NIH gives PITT $13 million grant for chronic obstructive pulmonary disease research

...erstanding of and improve outcomes for people with chronic obstructive pulmonary disease (COPD), a degenerati...capacity over time and includes conditions such as chronic bronchitis and emphysema. "COPD damages the lung tissue, expanding and breaking down the walls of ...

Brain cleaner

...gitis or nerve gas. It may also have an impact on chronic diseases such as glaucoma, amyotrophic lateral sclerosis (ALS) or HIV dementia. Teichberg: "Our method may work where others have failed, because rather than temporarily blocking the glutamate's toxic action with drugs inside the brain, it clears th...

Researchers develop new strategy for the treatment of CML

...eady shown impressive efficacy in the treatment of chronic myelogenous leukemia. Chronic myelogenous leukemia, or CML, is a cancer of the bone marrow caused by a specific genetic abnormality and is one of the more common forms of leukemia. Imatinib mesylate (Gleevec) is a highly effective anti-cancer agent...

Other highlights in the Jan. 17 JNCI

...pancreatic cancer, including cigarette smoking and chronic pancreatitis. The latter is marked by inflammation, suggesting that inflammation may be involved in the initiation or progression of pancreatic cancer. People with periodontal (gum) disease usually have high levels of certain markers of systemic infl...

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(Date:10/14/2014)... millions of years since T. rex took ... University scientists is breathing life back into dinosaurs using ... The research has important implications for how dinosaurs used ... the sense of smell and cool their brains. ... doctoral student Jason Bourke, lead author of the new ...
(Date:10/14/2014)... a new kind of stem cell that can become either ... vessels, according to a study published today in the journal ... cell type contradicts current theory on how organs arise from ... origins of, and future treatment for, liver cancer., Thanks to ... complex being made up of more than 200 cell types. ...
(Date:10/14/2014)... led by researchers at the University of Massachusetts ... Miller School of Medicine (UMMSM) have identified what ... (manic depressive) disorder, a breakthrough that could lead ... as well as depression and other related mood ... week in Nature Molecular Psychiatry , show ...
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