American Chemical Society's Weekly PressPac -- Aug. 8, 2007
...kinds of nanomaterials that luminesce, or glow, in clinical medicine and biomedical research. Those materials might, for instance, become a new generation of imaging agents that pinpoint the location of diseased tissue in the body. However, the question of whether these nanomaterials are toxic to living cells...NIH gives $8M to University of Pittsburgh School of Medicine for myositis research
... Researchers from the division of rheumatology and clinical immunology at the University of Pittsburgh School of Medicine are leading a worldwide effort to study a treatment for a rare autoimmune disorder called myositis, thanks to a five-year, $8 million contract from the National Institute of Arthritis and ...Study begins to reveal clues to the cause and progression of sepsis
...f Sepsis study (GenIMS), which collected extensive clinical and laboratory data geared to help analyze the ris... the first week of hospitalization even after the clinical signs of infection had subsided. Levels were highest in those with fatal severe sepsis, lowest in th...Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
...ently being tested against a variety of cancers in clinical trials. This study was designed to see if green ...e was due to random variation. This is the first clinical study to show proof that chemicals in green tea can increase detoxification enzymes in humans, Chow ...No evidence that widely prescribed statins protect against prostate cancer
...impact on the body, compared to outcomes seen in a clinical trial. Halls team studied the medical histories of 1,812 men, including 237 statin users, and analyzed their blood for free or unbound testosterone, for total testosterone, and for other associated compounds. The researchers found no relationshi...OHSU turns mouse into factory for human liver cells
...ng on only in rodents to be taken into a much more clinical setting. So I'm very happy about it." Arundeep S. Pradhan, director of OHSU's Technology & Research Collaborations office, which is responsible for transferring the university's research discoveries to the commercial sector, said market demand for ...Gilbert Foundation and American Fed for Aging Research award grants on Alzheimer's disease
... lack of reliable biomarkers which could track the clinical progression of the disease. Dr. Boutauds research seeks to quantify whether levels of secreted APP alpha and beta could serve as an effective biomarker for Alzheimers disease. This biomarker could potentially be used as a prognostic tool to track t...European Science Foundation's Forward Look reaches out beyond the endless frontiers
...he molecular and the cellular technologies and the clinical diagnostic nanotechnologies Recommendations on organization and funding of Nanomedicine-related research activities Proactive risk assessment for nanomaterials needed Recommendations on commercial exploitation, e.g. feasibility of ...New test improves detection of liver cancer
... the diagnosis of liver disease in compliance with clinical practice. The new results concerning HCC diagnosis provide an extra incentive for pursuing this development as intensively as possible. ...Brain blood flow gives clues to treating depression
...l decreases in blood flow, he reported. Currently, clinical psychiatry is based almost solely on subjective ob...ctive imaging evaluations could support subjective clinical decisions, he said. Using SPECT (single photon emission computed tomography)a molecular imaging/n...Study suggests estrogen deficiency can lead to obesity-induced high blood pressure after menopause
...e the controversial data about estrogen therapy in clinical studies, the results of this study performed in aged rats suggest that the loss of estrogens after menopause may contribute to the development of obesity and hypertension, opening new therapeutic approaches to postmenopausal hypertension. ...Female gender provides an advantage in renal diseases
...ilbiger's group is currently analyzing data from a clinical study of the osteoporosis prevention drug, raloxifene. As raloxifene has estrogen-like properties, the researchers hypothesized that raloxifene may affect the progression of renal disease in these women. Broad-based preliminary data from this study...Sugar and spice and everything nice: Health differences in newborn girls and boys
...a and offer a potential explanation for the poorer clinical outcomes found in infant females following cardiac surgery. Study 2: Lower Success Rates When Using Female Newborn Liver Donors As many as 500 children undergo liver transplantation in the US each year. Data on pediatric liver transplantation s...Almac Diagnostics announces pioneering genetic research on ductal carcinoma in situ
...rate the validation process and ultimately deliver clinical applications in this disease setting. said Paul Ha...velop a gene expression signature that will inform clinical treatment strategies" said Prof Adrian Harris, Cancer Research UK Professor of Medical Oncology at t...Other highlights in the Aug. 7 JNCI
...Xu Qu, M.D., and colleagues conducted a randomized clinical trial that examined whether four vitamin-mineral supplement combinations could effect the liver cancer death rate in a Chinese population that was deficient in many vitamins and minerals. Study participants took two or four of the following combinati...Gene variant is associated with brain anatomy, clinical course of ADHD
...attention, but also appears associated with better clinical outcomes among individuals with the disorder, acco...a gene] may also have a unique neuropsychological, clinical and pharmacological profile, although there remains considerable debate over the exact nature of thi...Link identified between Alzheimer's disease and glaucoma
...e in the eye (known as "intraocular pressure", and clinical treatments attempt to lower this pressure). Howeve... such drug, Bapineuzumab, is already being used in clinical trials to treat Alzheimer's patients by pharmaceutical companies Elan in Dublin and Wyeth in the US....Research team enlightens the reasons for severe blindness
...ed their permanent eyesight due to this therapy. A clinical study of twelve human patients is currently being carried out at a large-scale London hospital with encouraging results. If these findings prove to be withstandable, there will also be gene therapy available for LCA5 gene deficiencies in five to ten ...UCF research links proteins, stem cells and potential Alzheimer's treatment
...iasm with the caveat that more research, including clinical trials, will be needed should the next set of research benchmarks be met. Its one thing to be able to manipulate stem cells for creating specific tissue types the brain, the eyes, the heart but every disease is different, he said. Simply produci...Gene predicts better outcome as cortex normalizes in teens with ADHD
... the teen years in these children, coinciding with clinical improvement. Although this particular gene version... increased risk for ADHD, it also predicted better clinical outcomes and higher IQ than two other common versions of the same gene in youth with ADHD. Since...