Geneticists discover genes that make fruit fly hybrids sterile
...bilities. However, when Barbash and his colleagues cloned each gene and inserted an Lhr gene from D. simulans into D. melanogaster , the two genes did not interfere with each other in the engineered D. melanogaster strain even though the Lhr and Hmr genes interfere with each other in hybrids. "This tel...Authoritative new book on epigenetics published by CSHL Press
COLD SPRING HARBOR, N.Y. Mad cows, cloned embryos, cocaine addicts, calico kittens, and identical twins: all of these living creatures have epigenetics to credit for some quirky characteristics. Epigeneticsthe study of heritable traits that are not attributable to alterations in DNA sequen...Committee review of stem-cell fraud finds editors followed all rules
...y capable of becoming any cell in the body, from a cloned human blastocyst. The 2005 paper purported to describe the isolation of the first human embryonic stem cell lines specifically tailored to match the nuclear DNA of patients, both male and female of various ages, suffering from disease or spinal cord ...Wheat gene may boost foods' nutrient content
...ulture; and the University of Haifa in Israel have cloned a gene from wild wheat that increases the protein,... age of five lack an adequate protein supply. The cloned gene, designated GPC-B1 for its effect on Grain Protein Content, accelerates grain maturity and incr...New vaccine stimulates colorectal cancer patient's immune systems to fight cancerous cells
...ibody contained in the vaccine, called 105AD7, was cloned from a patient who survived seven years with liver metastases from colorectal cancer, Durrant explained. "This is very unusual as most patients die within one year of getting liver metastases," she said. "I thought if this antibody had helped this p...Neanderthal genome sequencing yields surprising results and opens a new door to future studies
...s and other problems. Once the Neanderthal DNA is cloned using our method, we have it forever, and we can recover specific sequences from the library whenever they are needed." Since the findings reported in this Science paper suggest that only about 0.5-percent of Neanderthal genome differs from the hum...Tarantula venom and chili peppers target same pain sensor
...nerve cells known as the capsaicin receptor, first cloned in 1997 in the Julius laboratory. In the last 10 years, Julius and his colleagues have demonstrated that this and related receptors trigger nerves to fire pain signals when exposed to Death Valley-like heat or the fiery properties of peppery food, mu...There's much more to bees than honey
...of telomerase is also critical for the survival of cloned animals. The discovery of a simple telomere system in the honeybee allows study of the role of telomerase in the very different ageing of the three bee castes....Caterpillars tell us how bacteria cause disease
...a and created a DNA library of over 1,500 separate cloned fragments which covers most of the genome. They then inject the clones into Tobacco Hawkmoth Caterpillars to study the effects. Their work has shown that clones containing harmless genetic material are recognised and destroyed by the caterpillar's...Cloned mice created from fully differentiated cells, a milestone in cloning research
...ng evidence that Dolly the sheep and other mammals cloned by somatic cell nuclear transfer were most likely ...e donor somatic cell it is an identical copy. This cloned embryo is then implanted into a surrogate mother, and, if the process is successful, is carried to t...Researchers discover that sheep need retroviruses for reproduction
...ed to the death of Dolly, the world's first mammal cloned from an adult cell. The idea that endogenous retroviruses are important for reproduction in mammals has been around for about 30 years, Spencer said. Studies in cultured cells have shown that a protein of a human endogenous retrovirus might have a ro...Gabriela Cezar's stem cell research targets birth defects and cancer
...otland's Roslin Institute (birthplace of Dolly the cloned sheep) and creating in-vitro models of obesity and Parkinson's Disease for the pharmaceutical giant Pfizer, Gabriela Cezar has returned to the University of Wisconsin-Madison. Not just any university could lure such a talented researcher away from ...UCLA researchers transform stem cells found in human fat into smooth muscle cells
...confirm the transformation, Rodriguez and her team cloned one of the primitive stem cells from the adipose tissue and repeated the experiments on a cloned population of cells with similar results. "We wanted to make sure it wasn't an isolated case or p...How purple corn and RNA break genetic laws
A newly cloned gene in corn will help explain how unusual interac...p1's location on one of the corn's chromosomes and cloned the gene. The mop1 gene makes an enzyme called RNA-dependent RNA polymerase (RDRP). Mutant mop1 gene...Researchers unveil strategy for creating actively-programmed anti-cancer molecules
...odies are produced in the laboratory from a single cloned B-cell, the immune system cell that makes antibodies. "By bringing together chemistry and biology, our approach provides a way to break the traditional one antibody-one target axiom of immunochemistry," said Lerner. "This new hybrid technology off...Novel connection found between biological clock and cancer
...ture compensation. For this study, the researchers cloned the gene based on its position in the genome, and found it was an important cell cycle regulator. When they eliminated the gene from the genome, the clock was normal, indicating that the mutation interfered in some way with the clock, rather than sup...Ten years later, 'Dolly' is still making headlines
...cher for the team who - 10 years ago - created the cloned sheep "Dolly," will kick off the 2006 American Ass...ns were just announced to create the world's first cloned human embryonic stem cells, and Dr. Burt Adelman of Biogen Idec, the company that produces the recen...Newly identified protein complex sheds light on axon growth mechanism
...ner, from the University of Zurich in Switzerland, cloned and characterised UNC-69, a previously known protein that had never been characterised. By studying mutants lacking unc-69 they show that the protein is widely expressed in the C.elegans nervous system and is required for normal axon development. Hen...Neurons find their place in the developing nervous system with the help of a sticky molecule
...reach their normal destination. The MDGA1 gene was cloned and characterized first in rat by O'Leary and two former postdoctoral fellows, E. David Litwack, Ph.D. and Matthias Gesemann, Ph.D. They showed that MDGA1 is a cell adhesion molecule a protein enabling cells to attach to other surfaces, something th......phatidylinositol (GPI) anchor1 (MDGA1), a recently cloned Ig cell adhesion molecule. This glycoprotein is anchored to the extracellular membrane by a GPI linkage and is similar in structure to Ig-containing cell adhesion molecules such as L1. Because layer 2/3 mouse neurons expressed MDGA1 during developmen...