Preclinical study links gene to brain aneurysm formation
...ysm formation, he adds, this study is an important clue because it links a known gene with a known function to an increased risk for intracranial aneurysm formation. Abruzzo says this study supports the idea that the NOS-3 gene is just one step in a complex molecular pathway that links flow-dependent v...Immunity in social amoeba suggests ancient beginnings
...um) is not only surprising but it also may prove a clue as to what is necessary for an organism to become multicellular, said the Baylor College of Medicine researcher who led the research that appears today in the journal Science. Dictyostelium discoideum usually exists as a single-celled organism. How...Scientists a step closer to understanding how anaesthetics work in the brain
An important clue to how anaesthetics work on the human body has been provided by the discovery of a molecular feature common to both the human brain and the great pond snail nervous system, scientists say today. Researchers hope that the discovery of what makes a par...Protein pulling -- Learning how proteins fold by pulling them apart
...he order of the amino acids in the strand gives no clue about how a protein functions. That's because every protein folds into a three-dimensional shape within about one second of being made, and it is this shape that dictates the protein's function. By studying how much free energy it takes for a prote...Penn researchers discover how microRNAs control protein synthesis
...binding domain of the EIF4E protein that offered a clue as to why the miRNA-Ago2 complex blocked protein production. When the miRNA-Ago2 complex pairs with a messenger RNA, Ago2 engages the cap of the RNA, explains Kiriakidou. We believe this results in competition with eIF4E and disrupts the normal ini...New clue why MS affects African-Americans differently than Caucasians
...s (MS) compared to Caucasians, possibly offering a clue why African Americans experience more disability with MS than Caucasians, according to a study published in the July 3, 2007, issue of Neurology, the medical journal of the American Academy of Neurology. For the study, researchers compared levels o...St. Jude study shows genes play an unexpected role in their own activation
...P to put CREB to work, Brindle said. It is another clue to how CREB might activate the genes for enzymes that make glucose in the liver, while activating different genes in the brain that are key to learning and forming memories. A long-term implication of this work is that one day it might be possible ...Researchers isolate new risk marker for overweight children
...earchers believe they've found a new and important clue to better understand how some adults are more susc...tor said. "A marker such as apoB48 may be just the clue we need to determine whether or not you are at risk, and, if you are, the best methods we can prescr...Analysis reveals extent of DNA repair army
...ogen pathway," he said. "I think this may be a big clue about how BRCA1 has breast specificity for tumorigenesis." That is important, Elledge explained, because one of the big unanswered questions about BRCA1 is why it acts to suppress only some forms of cancer: The gene is "common in (all) cells, so why ...From the deep -- Researchers find new species of sea anemone
... and comparing the anemones' genetic sequences may clue the researchers in to how the different species evolved over time....Susceptibility to Crohn's disease -- an important new clue
... of Lige, Belgium, have now uncovered an important clue to the susceptibility of individuals to this disease. In a genome-wide association study with more than 300,000 single nucleotide polymorphisms (SNPs) DNA sequence variations occurring when a single nucleotide in the genome differs between members...Post oak grasshoppers emerging
...ns. The chickens readily ate them, giving Behmer a clue that they are not toxic to other animals. Normally, chickens will not eat what will harm them, Behmer said. Behmer is still not sure what the Easter weekend cold snap will do to the grasshoppers' population, but he wants to study that too. Junek s......the ability to reproduce at high temperatures? A clue to the answer comes from the wild populations in which the mutation was not found: those living in Arizona and Utah. Could the bacterial mutation confer a competitive advantage that's only relevant in cooler climates? To find that out, the researcher...Cure for cancer one step closer
...can play a part in the cure. Every cell contains a clue that can make a difference to tomorrow's cancer patients," he said. Queensland is well placed as a source of cancer tissue due to its diverse population, large number of aged retirees, and high-rate of some cancers, particularly melanoma. The Wesle...Tiny clue reveals new path toward heart disease
...chers who led the study. Further study of this new clue could lead to novel ways to treat or even prevent the disease, the researchers said. "The ultimate goal is to determine who will develop cardiovascular disease," said lead study investigator Liyong Wang, Ph.D., a research associate at the Duke Cen...MIT biologists solve vitamin puzzle
...tor is used as a substrate," she said. One early clue to BluB's function was that a gene related to it is located near several other genes involved in B12 synthesis in a different bacterium. Still, the researchers were not convinced that one enzyme could perform all of the complicated chemistry needed t...Mitochondrial genes move to the nucleus -- but it's not for the sex
...week's Science that they've uncovered an important clue in flowering plants. "Plants that reproduce clonally or are capable of self-pollinating have transferred more genes from the mitochondrion to the nucleus," said graduate student Yaniv Brandvain, lead author of the paper. That discovery, Brandva...One Wwox isn't enough (to protect against cancer)
...m. "These mice have given us a very interesting clue that loss of both copies of Wwox gene may initiate tumors in the bone." This study initially set out to prove that Wwox is a bona fide tumor suppressor gene. The gene is missing or altered in 85 percent of lung cancers, 65 percent of breast cancer...Animal studies in the land of the midnight sun illuminate biological clocks
... the nearness of the sun to the horizon could be a clue to animals, and even plants, to keep on a 24-hour schedule." Folk found that several other scientific teams have also proposed the same theory. "Our work shows that clocks are important, and for me it means that you get surprises -- I thought th...Discovery could lead to better control of hemorrhagic fever viruses
...online by the journal Nature on February 7, give a clue to the high lethality of New World arenaviruses, suggest a way of reducing the severity of infection, and point the way toward a sorely needed treatment strategy. The four viruses, known as the Machupo, Guanarito, Junin and Sabia viruses, cause Bo...