Commandeering cellular machinery: recognition mechanism to detect small molecules
... detect small molecules in a robust way that could complement or replace other detection technologies," he explained. The same technology could also be used to produce enzymes, and to regulate metabolism in cells, Doyle said. Having demonstrated the ability to re-engineer one nuclear receptor to respond to a sm...New genetic tools provide clues to the effects of exercise and diet on obesity, diabetes
...fflux," Hittel said. These biochemical adaptations complement existing molecular models for improved glucose tolerance with exercise intervention in pre-diabetic individuals, he noted. On the proteomics side, the researchers analyzed gene expression and protein profiles from muscle of lean and obese an...US Agency for International Development awards $34 million to Virginia Tech
...nd outside the classroom," said De Datta. "We will complement and reinforce the strengths of our development partners who depend upon this knowledge: host country institutional partners, the NGO community and private sector, the donor community, and our research partners in universities, the National Agricultur...Report: How 10 top new technologies will help world reach globally-agreed goals by 2015
...n new tools for health and development in order to complement existing technologies and energize the field of global health." The report says most governments in developing countries and the international donor community have seriously underestimated the value of investing in health. The Commission on Macroecon...Mitochondria findings may help beat wide range of disease
..., they pass along to each "daughter" cell the full complement of mitochondria necessary for healthy cell physiology. Recent research suggests that when this process goes awry, healthy cells die, resulting in diseases ranging from optic atrophy (the most common inherited form of blindness), to Charcot-Marie-Toot...Rutgers is on the 'NIH Roadmap'
...ield of proteomics the study of the ever-changing complement of proteins that direct the activities of living cells. Understanding protein structure, function and interactions can lead to an understanding of the molecular basis of disease. Principal investigator Ronald Levy, co-director of the BioMaPS Institu...ENCODE consortium publishes scientific strategy
...chnology development grants, which are intended to complement the first set of technology development grants made in 2003 by adding more novel methods and technologies to the consortium's "tool box." "These grants are aimed at broadening the types of functional elements that we are studying under ENCODE and als...Clues to improving TB treatment
...acetone will not be the only compound to give as a complement of the ETH treatment, but it is a good start to help combinatorial chemists to develop derivatives," Baulard said. Although the researchers believe that their findings will prove most immediately useful for the treatment of resistant forms of ...New center to map DNA of key lab mice
...ut this work alone. We're coordinating our work to complement other projects, especially the Human Genome Project, which is where we expect to see the most return on our investment," said Dr. Schrader....Biodiversity: measuring up to the loss
...ity. Butchart et al. argue that Red List Indices complement indicators based on population trends, because although the indices show coarser temporal resolution, they have much better geographic representation; they're based on nearly all species in a group worldwide rather than on a potentially biased subset...Trojan-horse therapy blocks buildup of Alzheimer's plaque
...Crabtree said that the Trojan horse approach might complement other treatments being tested for Alzheimer's disease. These include anti-inflammatory treatments to prevent neuronal cell death from toxic aggregates, inhibitors of aberrant molecular signaling pathways in Alzheimer's, and vaccines to trigger antibo...First Max Planck Partner Institute in China
...on euros. The new research institute will not only complement the wide range of experimental topics at the SIBS ...itute for Computational Biology will round off and complement research activities at the MPG and the CAS. By establishing a Partner Institute both organizations a...Census of Marine Life - Discoveries and Highlights 2004: Scientists add 4m+ records, 13,000 species
... the Antarctic and Southern Ocean. To complement ongoing fieldwork, Census researchers are compiling data on marine animal populations from the past 500 or so years (HMAP) and developing models to help foresee life in the world's oceans of tomorrow (FMAP). Discoveries 2004 Modern ...Efforts to clone primates move forward
...ion by a sperm cell, which would provide a similar complement of chromosomes. In other animal cloning work, eggs had been enucleated at metaphase II, part of the second stage of meiosis. Once the maternal genetic material was removed, it was replaced by donor nuclei from rhesus cumulus and fibroblast cells. Cu...NASA's aura satellite sheds new light on air quality and ozone hole
...ra's view of the atmosphere and its chemistry will complement the global data already being collected by NASA's other Earth Observing System satellites. These projects are Terra, primarily focused on land, and Aqua, which comprehensively observes Earth's water cycle. Collectively, these satellites allow scienti...Gorillas in the midst of extinction
...surveys on the ground," said Laporte. "They really complement each other. The rate of change is so rapid that we need satellite imagery in a timely fashion to address the problems in the area. Aerial imagery is too expensive." Since gorilla habitat crosses three different countries, satellite imagery provides...NJIT astrophysicist who revived earthshine named fellow of American Physical Society
...s believed that earthshine's measures are a useful complement to satellite observations for determining Earth's reflectance of sunlight. Long-time observations of earthshine thus monitor variations in cloud cover and atmospheric particles known as aerosols that play a role in climate change....Research identifies promising route for treating age-related hearing loss
...ion of the brain. Normally, humans are born with a complement of about 50,000 hair cells. But since the cells do not regenerate, the steady rate of hair-cell loss that can accompany aging produces significant hearing loss in about a third of the population by the time they reach 70-years-old. Chen did a broad s...New nicotine-like imaging agent holds promise in PET studies, may help diagnose Alzheimer's disease
... interventions for nicotine addiction and possibly complement the diagnosis of certain forms of lung cancer, acc...ew fluorine-18 labeled imaging agent, nifrolidine, complement other ongoing positron emission tomography (PET) studies currently underway with nicotine-like PET i...Joslin scientists show knocking out two key signals will cause diabetes
...associated with diabetes. Thus, these two pathways complement each other, each controlling a part of the metabolism that is disrupted in type 2 diabetes or the metabolic syndrome." Others involved in the study were lead author Cullen Taniguchi, M.D., Ph.D., and former Joslin researcher Kohjiro Ueki, M.D., Ph.D....