Researchers turn to brainpower to beat dementia
...olunteers." The results of the Mensa research will complement data collected from an earlier University of Manchester study of some 2,500 elderly people that has taken place over the last 20 years. That research has already uncovered two genes associated with general cognitive ability, while work elsewhere over...New DNA studies verify existence of three right whale species
...de polymorphisms, more popularly known as SNPs, to complement one another, found that both kinds of markers support the listing of the North Pacific right whale (changed from the North Pacific population of Eubalaena glacialis to Eubalaena japonica, the North Pacific Right Whale) as its own taxon. The analysis ...New findings lead researchers to question basic assumptions of fisheries management
... how you manage the fishery, you can't have a full complement of age classes unless some part of the population is off limits." Other research presented at the symposium includes new findings about genetically distinct populations within the geographic ranges of some marine fish species, as well as evidence tha...Gladstone scientists announce new version of bioinformatics software program
...ll changes in expression. In fact, the two methods complement each other in interpreting biological data. GenMAPP was developed with grant support from the NIH. Any scientist can use it to modify MAPPs to fit other hypotheses, to design new pathways, or to share the data with others in the research community. T...Researchers identify gene that plays major role in age-related blindness disease
...have shown that a variant, or polymorphism, of the complement factor H gene, which alters a protein whose normal... or protection from -- diseases. In this case, the complement factor H (CFH) SNP associated with AMD encodes for a different amino acid, as histidine substitutes ...Gene variant increases risk of age-related macular degeneration
...the elderly. A common variant of the gene, called complement factor H (CFH), explains approximately 43 percent ... and first author on the report. "The finding that complement factor H is an important contributor to the disease suggests that inflammation may be a more importa...NIH should take decisive steps to promote independence, originality
...es in the design and direction of their work. To complement existing NRSAs, NIH should create a new independent-research award that enables postdocs to identify, explore, and control their own projects under the mentorship of senior investigators. The new awards should be portable -- allowing selected postdo...Scientists solve structure of key protein in innate immune response
... have better chance to design a molecule that will complement the shape of the pocket."...A bacterial genome reveals new targets to combat infectious disease
...g-term symbioses, as the two partners increasingly complement one another's biochemical activities. Slatko and colleagues enumerate a variety of pathways that have either been degraded or preserved, and highlight patterns in the genome structure through comparisons with other bacteria. For example, Wolbachia ...New miniaturised chip dramatically reduces time taken for DNA analysis
...sensors have a probe containing DNA fragments that complement the DNA they aim to detect. For example, to detect Salmonella in a sample of mayonnaise, the probe has fragments of the type of DNA that complements that found in a group of genes that identify the bacteria. When the probe is submerged into the mayon...Ancient enzyme guides healthy eating in mammals
...itiation factor 2 (eIF2a). Mice without the normal complement of GCN2 in the brain failed to exhibit an aversion to imbalanced food, the researchers reported. The protein inactivation also led to a decline in modified eIF2a in a key part of the brain following consumption of an imbalanced meal. The findings rev...With a complement, the sperm gets the egg
...ane of the spermatozoa, where a protein called the complement regulator membrane cofactor protein (MCP) is expre... The authors have looked at the activation of the complement cascade, a cell-signaling pathway that is activated during immune reactions, but that was not known ...Variation in immune response gene causes age-related macular degeneration when triggered
...ibit the immune response known as the alternative complement cascade - thus making them more susceptible to inf...esearchers say most do not work on this leg of the complement system. The genetic pre-disposition to AMD exists in approximately half of the Caucasian population...NIH awards Georgia Tech/Emory $11.5 M for nano cardiology research
...actors contributing to early plaque formation." To complement gene expression studies using molecular beacons, the team will develop quantum-dot nanocrystal probes and use them to study protein molecular signatures of cardiovascular disease. Quantum dots are nanometer-sized semiconductor particles that have uni...Newly discovered genetic disease sheds light on body's water balance
...'s bedside in modern medicine. These two areas now complement each other and bench-to-bedside progress leads to more rapid advances that benefit our patients." The authors note in the New England Journal article, "The V2 receptor has been an important tool for understanding the physiology of water balance -- (A...Excess liver gene protects against high-fat diet
...essel plaques exhibited by animals with the normal complement of receptors. Remarkably, in mice fed a normal, balanced diet, the excess receptors worsened blood lipid levels, the researchers reported. The findings suggest that natural variation among individuals in the quantity of the liver receptors might lead...DOE JGI announces 2006 Community Sequencing Program portfolio
... Rutgers, The State University of New Jersey, will complement the knowledge already gleaned from rice, the only other monocot grain to have been sequenced to date. Sorghum, with its economic importance worldwide exceeding $69 billion per year, is expected to provide an improved blueprint for the study of other ...JCI table of contents June 1, 2005
...n of the airways. The role of one protein, called complement component C5, in asthma has remained controversial. In a study appearing online on May 12 in advance of the print publication of the June issue of the Journal of Clinical Investigation, Yi Wang and colleagues from Alexion Pharmaceuticals examine the ......r-assisted biology, the new research facility will complement the highly experimental range of issues covered at the SIBS in Shanghai, as well as a number of projects at Max Planck Institutes in Germany. Moreover, cooperative ventures are planned with the Shanghai-based Institut Pasteur of Shanghai, Chinese Aca......e measure of tuberculosis control and will ideally complement current drug-treatment strategies. The major roadblock in the development of new tuberculosis vaccines is the lack of understanding what constitutes protective immunity. Insights into the mechanisms of protection and disease progression will lead to ...