Proteins take on new roles in malaria parasite
... organisms need networks of proteins to accomplish complicated jobs, such as cell division or, in the case of the Plasmodium parasite, host invasion. Sittler explained the value of protein network analysis: "If you know certain proteins are involved in the invasion of red blood cells"--something that Plasmodium...Inherent vascular repair key to atherosclerosis
...tside to be a very complex disease may not be that complicated after all," Goldschmidt continued. "It turns out to be a series of events that make a lot of sense. The key is the body's reaction to tissue injury, which appears to be governed by certain sets of genes." He said that most people can cite an example ...Researchers devise dinosaur classification method
...said that the simple shapes of theropod teeth have complicated previous rigorous attempts to use them for classification. The mathematical tedium Smith claims to have spared while devising the methods was not lost on tooth examination: Smith collected measurements and curvature data from about 2,000 teeth, sc...A resetting signal keeps circadian rhythm on track in Drosophila fruit flies
...r, circadian brain anatomy in mammals is much more complicated and the tools much too primitive to allow a similar network approach at this time. Flies are state-of-the art. Fortunately, their circadian clocks and even neural mechanisms are quite conserved with mammals." "We were curious about how these brain ...Study links low selenium levels with higher risk of osteoarthritis
...ical examinations in North Carolina. He employed a complicated nuclear technique known as Instrumental Neutron Activation Analysis. "We found that when we divided the participants into three groups, those with the highest selenium levels faced a 40 percent lower risk of knee osteoarthritis than those in the lowe...Two genetic traits giving Africans malaria protection lose effectiveness when they occur together
...lliams said. "Our study shows that it can be very complicated to turn up genetic associations and properly understand them. If one trait can interfere with the effects of another, you may miss an association where one truly exists. Conversely, you may find a trait that seems to provide protection but not see ...War on terror meets war on cancer
...zer-Martin say the new findings might make it more complicated to determine where bacteria used in bioterrorism were grown. That isn't true of anthrax, which is spread by spores that are almost dormant. But for live bioweapons spread through the air in an aerosol mist bacteria that cause plague, tularemia or Q ...Biotechnology's newest chemical tool
...ferases, enabling real-time dynamic studies of the complicated mechanism of protein translation....New antibody shows promise as cure for anthrax
...terial culture, which could eliminate the need for complicated and expensive IgG production in mammalian cell culture. Drs. Jean Patterson and Ricardo Carrin at SFBR, along with veterinary staff from the SFBR Department of Comparative Medicine, have tested the re-engineered antibody with guinea pigs to determine...FDA approves AVELOX (moxifloxacin HCl) for treatment of complicated intra-abdominal infections
...(moxifloxacin HCl) for a new use the treatment of complicated intra-abdominal infections (cIAI) in adults. AVEL...ndicitis. [1] "The FDA approval of AVELOX to treat complicated intra-abdominal infections is welcome news, providing doctors with an effective treatment option for...Picking particles faster than one at a time
...eded is a high-resolution structure of a large and complicated biological molecule -- a ribosome, say, which combines protein and RNA, or a membrane protein that readily falls apart in water and is hard to crystallize -- biologists often turn to cryo-electron microscopy (cryo-EM) to perform single-particle recon...Watch your step when the going gets rough
Placing your foot accurately is a complicated process. If something moves where you plan to place your foot then you can adjust your step while your foot is swinging through. Experts thought previously that if nothing changed in the path, or in your plans, then the place where your foot will lan...The secret love life of plants
...f its development. In flowering plants, there is a complicated double-fertilisation mechanism that arises among embryos and endosperm. They develop together into mature seeds. The exact process, and the communication between the two parts of the seeds, has been unclear to scientists. Researchers at the Max Planc...'Computer-chemistry' yields new insight into a puzzle of cell division
...is interaction," he said. "Somehow these two large complicated molecules had to also interact specifically somewh...y, because there is no point of reference on those complicated shapes," Rudolph said. The researchers finally winnowed the possibilities to what Rudolph called "on...New UW study offers strategy for treatment of fatal nervous system disorder
...he enzyme directly to the brain and spinal cord is complicated by a natural barrier -- the blood-brain barrier -- that makes the delivery of agents like the enzyme to the brain difficult. "To eliminate the barrier, we changed the paradigm by transplanting enzyme-deficient cells into the brain and spinal cord of...New view of cancer: 'Epigenetic' changes come before mutations
... cell's nuclear DNA may have to give way to a more complicated view. In the January issue of Nature Reviews Genetics, available online Dec. 21, he and his colleagues suggest that cancers instead begin with "epigenetic" alterations to stem cells. "We're not contradicting the view that genetic changes occur in th...Advanced genomics and proteomics improve the diagnosis and treatment of a deadly lung disease
...piratory failure. Effective treatment, however, is complicated by the fact that a definitive diagnosis often requires a lung biopsy. "Unfortunately, many patients do not receive lung biopsies. As a result, about one-third of patients who come to our clinic have previously been misdiagnosed, and many have been tr...Rockefeller researchers discover a biological clock within a clock
... technique can provide useful information, it's so complicated that researchers rarely use it. And no one had ever thought to use it to follow proteins in a single cell for an extended period of time. "This begins to measure all these biochemical interactions inside the cell," Meyer says. For the first time, Pe...Scientists spot solitary stem cells in living bone marrow
...arkers found on the cell's surface. The process is complicated and the flow cytometry equipment used to sort the cells is expensive. Plus the sorting process removes stem cells from their natural bone marrow environment, which changes their properties in fundamental ways. To verify that cells identified with the......photosynthesis, but it looks like they have a more complicated metabolism than we initially suspected." All cells require nitrogen for making proteins and nucleic acids, but N2 gas from the atmosphere cannot be directly used for this purpose; it must first be reduced or fixed into larger, carbon-containing compo...