Joslin researchers pinpoint causes of adverse reactions to popular type 2 diabetes drugs
...patients at greater risk for weight gain, vascular complications and heart failure. Recently, the U.S. Food and Dru...mong patients who took RSG. While reports of these complications remain rare, GlaxoSmithKline has added a warning about the risks to the drugs' labels. Now a new stu...Gene therapy prevents the onset of diabetic symptoms in mice
...of the pancreas, causing chronic hyperglycemia and complications such as blindness, kidney failure, heart disease and nerve damage. Previously known as juvenile diabetes, type 1 diabetes is usually diagnosed at a very early age but is sometimes not diagnosed until the individual reaches adulthood. In this study, ...Hopkins researchers discover potential new approach to treating diabetes
...d sugar levels to stay too high, which can lead to complications like blindness, kidney failure and nerve damage. "Diabetes is a really big problem, even when patients are given insulin and stay on strict diets," says Carles Lerin, Ph.D., a postdoctoral fellow in cell biology at Hopkins and an author of the repor...Long-term study shows brain function not impaired by tight diabetes control and hypoglycemia
...ntrol significantly reduces the risk of developing complications of diabetes such as eye, kidney and nerve disease. But the DCCT also showed that tight control -- achieved by taking three or more insulin injections daily -- can come at a cost: Patients in the trial who kept their blood glucose levels as close to t...New therapy may mean less dietary restrictions for celiac sufferers
...yme therapy that may prevent the many symptoms and complications of this widespread disease. People with celiac sprue, also called celiac disease, cannot tolerate the protein gluten in their diet. Gluten is present in grains like wheat, barley, and rye. When gluten is ingested by a celiac patient, it sets off an ...New tool tracks brain development in babies
...en and nutrient deficiency, usually as a result of complications during delivery. Hypoxic ischemic injury can result in severe motor problems. "The pattern and extent of the brain injury largely determine the neurological and developmental consequences for the newborn," Dr. van Pul said. "The detection of injury a...Progress being made in exploring potential use of stem cells to treat heart disease
... cells within patients' heart tissue to avoid such complications as arrhythmias (irregular heart beat) Solving immunological issues surrounding rejection "Exciting new findings over the past 5 years indicate that stem cells could prove effective as protective or regenerative cardiac therapies," says Ivey, who w...Nearly two-thirds of babies receive most of the recommended newborn screening tests
...s will die or develop brain damage or other severe complications from these disorders because they are not identified in time for effective treatment, the March of Dimes says. The March of Dimes and the American Academy of Pediatrics have endorsed the recommendation of the American College of Medical Genetics that...New procedure safer for detecting fetal anemia
...ng red blood cells in the fetus, which may lead to complications including miscarriage, fetal anemia, fetal heart failure and severe jaundice in the newborn period. Researchers studied 187 mothers-to-be who had been diagnosed with Rhesus disease, one cause of fetal anemia. This condition allows antibodies to en...Equine Medical Center records successful year for neonatal foals
...born too early. When that happens, serious medical complications may arise. "Neonatal disease can range from min... are often suffering from respiratory problems and complications like infections and cardiac problems are also a threat. Treating a neonatal foal is an intensive ...Researchers develop novel mouse model to witness immune system attack on chlamydia
...s. "These undiagnosed infections over time lead to complications like tubal pregnancy and infertility. The goal would be to vaccinate young people to keep them from suffering from undiagnosed infection and the bad outcomes associated with it." Most pathogens (disease-causing bacteria or viruses) enter a host by ...New test could keep babies from contracting deadly infections
...who develop sepsis, meningitis, pneumonia or other complications from group B streptococcus, about 15 percent die, according to the American College of Obstetricians and Gynecologists. Federal guidelines require doctors to screen all women for the organism between 35 and 37 weeks of pregnancy. Women who test pos...Early treatment prevents lasting breathing problems in some premature babies
...o prevent these potentially debilitating long-term complications have yielded conflicting results. Supported by the...itical that we develop ways to prevent many of the complications related to prematurity so that these children can lead healthy, robust lives," NIH Director Elias A....Thrombosis in children with leukaemia
...nd focused therapy are essential in order to avoid complications that may turn out to be extremely harsh. What is t...ise way the association between ALL and thrombotic complications in 1,752 children affected by this type of leukaemia. Data were taken from 17 international studie...Fitness level affects bariatric surgery outcomes
...r cardiopulmonary fitness may experience increased complications after bariatric surgery. New research published in...nger operative times and suffered more postsurgery complications than patients with higher fitness levels. Bariatric surgery, a procedure that involves surgically sh...New company will seek drugs against diabetes and cancer
...apted to screen for drugs that could alleviate the complications of diabetes. "People with diabetes can go blind, their kidneys can fail and their nerves can die," says Baranski. "We don't have any good drugs for counteracting these effects. We know that high blood sugar contributes to these problems, so I went...Researchers discover genetics markers to help predict risk for preterm birth
...ample of how heredity may play a role in pregnancy complications and how genetic factors can contribute to racial disparities in the incidence of preterm birth," said Dr. Strauss. "With better understanding of this genetic variation, we hope to be able to identify pregnancies at greater risk of preterm birth and i...For low-risk women, risk of death may be higher for babies delivered by cesarean
...m births with no indicated medical risk factors or complications of labor and delivery) nearly doubled. "These findings should be of concern for clinicians and policy makers who are observing the rapid growth in the number of primary cesareans to mothers without a medical indication," says lead researcher Marian ...Molecules in blood foretell development of preeclampsia
...increases the risk of death, and for such lifelong complications as blindness, cerebral palsy, and learning disabilities. In such instances, physicians are forced to weigh the mother's risk of severe disease or eclampsia against the consequences of preterm birth for the baby. In the current study, the researche...Amgen launches Aranesp prefilled Sureclick autoinjector for treatment of anemia
...time. Patients with CKD often suffer from serious complications such as anemia, which occurs when failing kidneys no longer produce sufficient erythropoietin, a hormone that stimulates the production of oxygen-carrying red blood cells. Red blood cells contain hemoglobin, a red, iron-rich protein that carries oxy...