Study begins to reveal clues to the cause and progression of sepsis
...lts, treatments that completely abolish a specific component of the inflammatory response would be ineffective, and could be dangerous, since the inflammatory response is needed to address the underlying infection. Instead, they believe that therapies that address the chronic inflammatory response after sepsi...Bursts of waves drive immune system 'soldiers' toward invaders
...e. The cell-propelling circuit contains a third component that makes it self-sustaining. The researchers fou...nhibition of Hem-1 accumulation. The "recruitment" component was not directly observed, but is consistent with their observations and experiments. In the resea...News tips from the Journal of Neuroscience
... neuropathic pain, whereas animals lacking the MAC component C6 did not. Having ruled out C3a and the MAC as major pain effectors, the authors injected naive rats intrathecally with the C5a anaphylatoxin. C5a increased cold pain sensitivity, and a C5a receptor antagonist blocked this effect, consistent with a ...UCF research links proteins, stem cells and potential Alzheimer's treatment
... amyloid-precursor protein (APP), which produces a component of the plaques, a hallmark of Alzheimers, prevent stem cells from becoming neurons. The research team treated Alzheimers-model mice producing human APP with phenserine, which is known to reduce the amount of APP in the brain. The APP level in the ...How cells change the pace of their steps
...mutant strains that will permit us to dissect each component of the cell movement cycle, thus allowing us to understand the function of each biochemical part and how the whole system works in concert. As the Dictyostelium cells moved on the elastic substrate the researchers measured strain forces of as much...Marijuana component opens the door for virus that causes Kaposi's sarcoma
PHILADELPHIA The major active component of marijuana could enhance the ability of the virus that causes Kaposis sarcoma to infect cells and multiply, according to a team of researchers at Harvard Medical School. According to the researchers, low doses of -9 tetrahydrocannabinol (THC), equ...Altering a protein makes mice less fearful
...e and suggests that this protein may be a critical component of the brain systems that underlie innate fear. ...ibiting the ASIC1a protein in normal mice (using a component of tarantula venom) similarly blunted the innate fear response. "Showing that pharmacologically bl...Forsyth scientists gain new understanding of adult stem cell regulation
...g direct cell-to-cell communication are a critical component for development and normal physiology....Cost-effective method for gene silencing is featured in Cold Spring Harbor Protocols
.... The thymus is the organ where T-cellsa principal component of the immune system in vertebratesproceed through a strictly coordinated maturation process before being released into the bloodstream. Fetal thymus organ culture is the only system available for studying the complete program of T-cell maturation i...Research shows NPD1 protects a key component of vision
...thesis. They demonstrate that the endogenous toxic component (A2E) that accumulates in the retina during aging and in retinal degenerations, including those due to gene mutations, can be counteracted by NPD1. The LSUHSC research team conducted studies on the formation and action of NPD1 on a human transformed...Researchers find pathway that controls cell size and division
...ly shown to be involved in synthesizing a modified component of the cell membrane. The Levin labs data indicates the pathway also has a major role in cell division. So far this has been the only pathway thats been identified in bacteria that directly regulates cell size, says Levin. Typically, cells in nutr...Surprising new species of light-harvesting bacterium discovered in Yellowstone
...focused on two genes: 16S ribosomal RNA, a crucial component of the machinery used by all living cells to manufacture proteins; and the gene for a protein called PscA, which is essential for converting light energy into chemical energy. 16S ribosomal RNA is distinctive in each species. Says Bryant, "Finding...NCRR launches national network to connect investigators based at minority institutions
...on Minority Health and Health Disparities, another component of NIH, will contribute to the funding for the network. The infrastructure, particularly informatics tools, provided by the network will allow RCMI investigators to leverage more effectively the resources that are in place at their institutions ...UB scientist discovers novel iron-copper alliance
... is the workhorse of trace minerals. An essential component of red blood cells, disruption of iron levels in the body will result in a myriad of serious conditions, and life cannot be sustained without it. In novel research, investigators at the University at Buffalos School of Public Health and Health Profes...House backs taxpayer-funded research access
... research findings on the Internet is an essential component of our nations investment in science, said Heather Joseph, Executive Director of SPARC (the Scholarly Publishing and Academic Resources Coalition), and a leader of the Alliance for Taxpayer Access (ATA). This action paves the way for all scientists a...Mucins stand guard against gut infections
...emonstrate that cell surface mucins are a critical component of mucosal defense, and the role of these proteins in epithelial infections and inflammatory disease should be further examined. ......uccess of their new technology in analyzing a rare component of a complex microbial community and there is plenty more to explore. Quakes team has already begun using the chip to isolate, identify, and sequence communities of microbes that reside in termite hindguts, and his lab at Stanford is custom buildin...JCI table of contents: July 19, 2007
...emonstrate that cell surface mucins are a critical component of mucosal defense, and the role of these proteins in epithelial infections and inflammatory disease should be further examined. TITLE: MUC1 cell surface mucin is a critical element of the mucosal barrier to infection AUTHOR CONTACT: Michael A. ...Restless legs genetics on the move
...y members who are also affected, so that a genetic component was assumed to be involved in the development of the disease at an early stage. Various groups of scientists have been looking for the genes which might play a role in RLS for years. A team of scientists from the Institute of Human Genetics of the...Measuring the unseeable: Penn researchers probe proteins' dark energy
...relation between a change in calmodulins entropy a component of its stored energy and the total entropy change...gible, says Wand. But now its clearly an important component of the total energy in protein binding. Because of this new information, the researchers suggest ...