Tag: "compounds" at biology news
Antioxidant found in many foods and red wine is potent and selective killer of leukemia cells
...hat anthocyanidins, a group of naturally occurring compounds
widely available in fruits and vegetables as well as red wine, have chemopreventive properties, Dr. Yin and his collaborators studied the effects and the mechanisms of the most common type of a naturally modified anthocyanidin, known as cyanidin-3-ru...
Deactivating protein may protect nerve fibers in MS
...w in the mutant mouse," Forte said. One class of compounds
Forte and Bourdette are particularly interested in is non-immunosuppressive derivative of cyclosporin A (CsA). Some nonimmunsuppressive derivatives of cyclosporin A are in human trials for other conditions. Because these drugs are already being teste...
Strawberry daiquiris -- the extra-healthy cocktail?
... a boost helped the berries resist decay, the same compounds
would also be expected to make the strawberries he... Coloured berry fruits like strawberries contain compounds
known as polyphenols and anthocyanins. Consumption of these compounds
has been linked to the prevent...
Researcher focuses on pros, cons of antioxidants from fruits and vegetables
...)." Phytochemicals, also called secondary plant compounds
including antioxidants have been defined as chem...cai, a palm fruit from Brazil, as well as isolated compounds
including quercetin and ellagic acid, which are also sold as dietary supplements. The results of ...
OHSU lab finds meth receptor that could lead to therapy
...nlans laboratory has synthesized more than 150 new compounds
that are being analyzed for their ability to selectively interfere with TAAR1 and block its activity. "So we're already on a roll," Grandy said. The goal is to "take them to the point where they can be tested in humans." Still, there's more to b...
Researchers from the UGR use a bacterium to obtain biopreservatives from food
...ne of these strategies is to produce antimicrobial compounds
such as antibiotics, certain metabolism products, lytic agents, numerous types of protein exotoxins, and bacteriocins. It has become increasingly more necessary to find new antimicrobial agents because of the stronger resistance acquired by bacteria....
Enhancing chemotherapy's efficacy: New agent has synergistic effect with standard drugs
...as taxanes (Taxol and Taxotere) and vinca-alkaloid compounds
such as vincristine. This synergistic effectin whi...cells. "Together, these findings indicate that MCP compounds
have potential to be effective in combination with other anticancer agents," the authors concluded. ...
EPA selects Phylonix to screen compound library in zebrafish
...s part of the agencys ToxCast project to correlate compounds
having known toxicities with biological activities...x component of the ToxCast program is to correlate compounds
having known toxicities with biological activities in zebrafish test systems. Numerous mechanisms a...
Anti-wrinkle compound causes pathological reaction in skin cells
...eauty products, continues the researcher. "Several compounds
found in cosmetics are just as complex as medicationthey are absorbed through the skin, flow through the bloodstream, are expelled by the kidneys, or stocked in cells or even in the liver. Yet, the laws regulating their use are far less restrictive t...
Study shows isolation of stem cells may lead to a treatment for hearing loss
...end goal, but the exciting part is now we can test compounds
that could promote regeneration of hair cells from these precursor cells in vitro, we can study the genes expressed during the transition from stem cells to hair cells, and we can think of developing strategies for cell replacement, i.e. transplantin...
Discovery in plants suggests entirely new approach to treating human cancers
... out a new direction for us to develop therapeutic compounds
targeting ubiquitin ligases." The scientists extracted and purified TIR1 from the common plant model Arabidopsis. By x-raying crystals of the protein, Zheng, Estelle and colleagues determined the enzyme's three-dimensional structure -- a first for...
Leading researchers honored for progress in cancer prevention, detection and treatment
...al strategies using a variety of chemopreventative compounds
for targeting reduction of liver cancer in the economically developing world, Kensler will present his lecture on "Translating molecular targets for chemoprevention into interventions for at-risk populations" at 2:15 p.m. on Tuesday, April 17, in Hal...
Natural anti-freeze -- how arthropods survive the cold
...mperatures. These creatures accumulate anti-freeze compounds
which lower the temperature at which their bodies freeze, meaning they can withstand temperatures as low as minus 30C. Within this population there is a clear divide into less- and more-cold hardened animals, which has been a puzzle to researchers. H...
Getting dirty may lift your mood
...ne if M. vaccae, other bacteria, or pharmaceutical compounds
have antidepressant properties through activation of this group of serotonin neurons....
New chemistry approach promises less expensive drugs
...ew reactions that will streamline the synthesis of compounds
that are relevant to human health." Most drug mo...bstantial impact on the discovery of new bioactive compounds
for the benefit of society." MacMillan said he hopes the findings would eventually make drugs both...
All roads lead to GUN1
...nergy carbon dioxide from the air into high-energy compounds
like glucose and starch. With chloroplasts being a plant's basic lifeline, it is crucial for a cell to be informed about their functional state. In earlier work, Chory's lab discovered that one important function of retrograde signaling that is fr...
Light-activated therapy targets DNA components
...ivering the anticancer drug cisplatin and improved compounds
to a disease site. In the process, the coupling of the drugs to the designed molecule increased water solubility. The improved selectivity along with photoinitiation reduce damage to healthy tissue. The paper, Synthesis, characterization, DNA bindi...
Toward improved forms of a time-tested cholesterol-fighter
... or breakdown carbohydrates, fats and protein into compounds
that the body needs to maintain good health. In th...ther pharmaceutical companies have reported on new compounds
for these targets in the open literature, although some patents have appeared. ...
News tips from the Journal of Neuroscience
...f subjects, but perhaps not those trying to design compounds
to treat chronic pain. 2. Rho, Endocytosis, and Oligodendroglial Membrane Growth Angelika Kippert, Katarina Trajkovic, Lawrence Rajendran, Jonas Ries, and Mikael Simons When forming myelin, oligodendrocytes have a big job in creating all that...
Plastic that degrades in seawater could be boon for cruise industry and others
...epending on the composition of the plastics, these compounds
may include water, carbon dioxide, lactic acid, glycolic acid, succinic acid, caproic acid and L-lysine, all of which can be found in nature, they add. Because the new plastics are denser than saltwater, they have a tendency to sink instead of flo...
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