Old drug, new tricks: Prospects for slashing the impact of malaria
...rst, PNG is a relatively confined area with a high concentration of all four types of global malaria unlike Africa, where one type predominates. Second, outstanding field researchers with clinical trial capability from the PNGIMR can collaborate with world leading Australian experts in malaria from WEHI and the U...Nanostructured Materials: Environmental, Energy and Sensing Applications
...e needed either to precisely control the pollutant concentration in the atmosphere or to control the gas concentrations of emissions of combustion processes for subsequent pollutant removal. In this direction, as an example of how the materials design is paramount, the use of nanostructured materials has been dem...'Mad cow' proteins successfully detected in blood
...ow many people may be incubating the disease. "The concentration of infectious prion protein in blood is far too small to be detected by the methods used to detect it in the brain, but we know it's still enough to spread the disease," said UTMB neurology professor Claudio Soto, senior author of the Nature Medicine...Detecting anthrax proteins at ultralow concentrations
...ection. This change in current flow depends on the concentration of the proteins in the solution and can detect amounts as low as 10 picomolar (trillionths of a mole). "We hope this system will lead to a method for rapidly screening agents that inhibit the binding of LF or EF to these pores," says NIST's lead inve...System drastically cuts down botulism detection time
...m dot is measured on the bead and can quantify the concentration of the toxin. The BEADS system has been commercially licensed to a few companies. In addition to detecting botulinum, the system can be tailored to detect multiple pathogens or toxins, such as E. coli, salmonella and ricin, simultaneously....Roadways and parking lots threaten freshwater quality in the northeastern US
...y of Baltimore. By looking at records of chloride concentration in a range of northeastern waterways-- from urban ...r salinity reached levels equivalent to 25% of the concentration of seawater. In developed areas of Baltimore, chloride concentrations were already high enough to in...Smoking damages key regulatory enzyme in the lung
...ck the enzyme, also shows that smokers had a lower concentration of the tracer in the bloodstream than nonsmokers d...le-body PET imaging, researchers could measure the concentration and movement of the radiotracer and MAO A, a subtype of the enzyme crucial to mood regulation and on...Climate change will affect carbon sequestration in oceans, model shows
... reliable projection of atmospheric carbon dioxide concentration and resultant climate change," Jain said. The model is described in the September issue of the Journal of Geophysical Research -- Oceans. Using the model, Jain and Cao studied the effectiveness of oceanic carbon sequestration by the direct injection ...Aspirin might prevent Vioxx cardiac damage
...ood clots. That decline occurs without a change in concentration of thromboxane, a related agent that constricts vessels and promotes clot formation. The new study found that, in a strain of mice prone to high blood pressure, an inability to respond to prostacyclin led to cardiac complications, including hypertens...Chemical imbalance may explain painkiller's cardiac danger
... blood clots. That drop occurs without a change in concentration of thromboxane, a related agent that constricts vessels and promotes clot formation. The new study by researchers at Duke University and Durham VA Medical Centers found that, in mice prone to high blood pressure, an inability to respond to prostacycl...New tooth enamel dating technique could help identify disaster victims
...ts and animals that live off plants, the carbon-14 concentration in our bodies closely parallels that in the atmosphere at any one time," he said. Buchholz and his colleagues analyzed 33 teeth from 22 different people whose ages were known. The enamel separations were done at the Karolinska Institute, and sample p...... play a role in this process. Increasing the salt concentration in the cell or decreasing the salt concentration around the cell leads to an influx of water. This principle is known as osmosis. Cells activate vari......, produce an effect of photo-sonoluminiscence. The concentration of ultrasounds by constructive interference generates a pressure front that produces a decompression of the gases dissolved in the water. This wave front produces a luminous plasma around the bubbles, as well as high pressure and temperatures. These ...Tips from the journals of the American Society for Microbiology
...e to the presence of inhibitory substances and low concentration of virus recovered. In the study researchers combined real-time reverse transcription-PCR (a promising method for detecting HAV due to its sensitivity, specificity, speed, and ability to deliver quantitative data) and immunomagnetic separation (I......Yet these improvements have mainly been due to the concentration of the industrial production, which in the majority of cases offers limited scope for the future. Results from this study are a source of concern. Unless significant improvements occur in the energy required per unit of product, the net energy requir...Cytokinetics presents data on CK-1827452
...to improve cardiac cell contractility increase the concentration of intracellular calcium, which indirectly activates cardiac myosin, but this effect on calcium levels also has been linked to potentially life threatening arrhythmias. In contrast, cardiac myosin activators have been shown to work by a novel mechan...UQ researcher tracking key to healing the brain
...ent has since been created thanks to having a high concentration of experts who specialise in different aspects of neuroscience research. "It is great to have so many people working on different aspects of the same problem, creating a unique synergy that is already producing results," he said....RNA all set to become a superstar
...attern. Tuschl comments further: "For example, the concentration of individual RNAs in the cells of certain tumors is noticeably high. This offers a completely new approach to fighting cancer." The Ernst Schering Prize is awarded annually to an internationally renowned scientist for outstanding achievements in the...... scale as the change in the bubble patterns is the concentration of dissolved carbon dioxide. According to the researchers, the work could be important in understanding bubbles formed of dissolved gasses in other situations, such as nitrogen bubbles that grow in the blood vessels of surfacing divers and can cause ...VCU researchers design new receptor and enhance bioassay to advance drug discovery process
...receptor we have created requires an extremely low concentration for the dye to be bound," said Sidorov. In current assays, researchers use high concentrations of probe DPX, a dicationic organic compound used to quench the fluorescence of pyranine. The affinity and specificity of DPX to pyranine is low. "The probl...