New approaches to endometriosis treatment -- mouse experiments point the way
... the work in humans. Our initial experiments have confirmed the presence of the dopamine receptor in human endometriosis, and therefore we believe that treatment with dopamine agonists will have the same effect on humans as it does on mice, she says. This is encouraging, since current therapies are still as...Translating form into function
... tested the prediction experimentally. The results confirmed the prediction. Almo, a professor of biochemistry at Albert Einstein College of Medicine, further confirmed the finding by determining the substrates atomic level structure through x-ray crystallography. To ...Double honors for diabetes researchers
...to nerve damage in diabetes. Further investigation confirmed the precise role these genes played. Dr Abbotts clinical research into the condition involved identifying the most effective testing methods for predicting foot ulceration caused by neuropathy and discovering that diabetes patients from South Asian...UN issues analysis of global investors' sustainable energy 'gold rush'
...l the November 2006 U.S. mid-term elections, which confirmed renewable energy as a mainstream issue, moving it up the political agenda. Also spurring the sectors growth has been the persistently high price of oil averaging more than $60 a barrel in 2006 (although one report conclusion is that the sector i...A faster way to recover from chemotherapy and marrow transplant
...was a surprise finding. A variety of experiments confirmed that prostaglandins, particularly dmPGE2, promote ...d stem cells in live fish. The researchers also confirmed their observations in mammalian models. When dmPGE2 was added to mouse embryonic stem cells in the l...Noninvasive screening in early pregnancy reduces Down's births by 50 percent
...ained from the Central Cytogenetic Registry, which confirmed the reduction in invasive procedures and the number of children born with Down syndrome at national level. When we looked further at the history of children born with Down Syndrome, we found that their mothers had declined the offer of screening, or ...Gum disease in postmenopausal women linked to oral bone loss
...spected oral pathogens and oral bone loss, results confirmed that the three control bacteria included in the study, which have not been associated with periodontal disease, also were not associated with oral bone loss. On the contrary, the two control bacteria -- S. sanguis and Capnocytophaga sp. -- were asso...High cholesterol diets modify gene expression in atherosclerosis
...ame conditions. After genetic analysis, scientists confirmed that regarding the samples (without cholesterol) modifications took place in birds fed with a high cholesterol diet. Differences show that cholesterol causes changes in messenger RNA synthesis in proteins related to lipid metabolism control, prolifer...Massive herds of animals found to still exist in Southern Sudan
...1 and 2002 of the wildlife populations in Boma and confirmed the presence of white-eared kob in considerable numbers. At the time, aerial surveys could not be conducted due to the ongoing war. We were amazed to see these large numbers of white-eared kob in Southern Sudan, said Marjan. Most people assumed we wo...BRCA2 carriers at increased risk for deadly form of prostate cancer
...t importance to study whether these results can be confirmed for carriers of mutations at other locations within the BRCA2 gene. Finally, the results indicate that in the search for new methods to predict prostate cancer progression, it may be fruitful to look for gene or protein expression patterns in prostat...ChemGenex announces publication confirming activity of Ceflatonin in T315I-Positive CML
...es (neutropenia, thrombocytopenia and anemia), but confirmed that the toxicity of HHT was "easy to manage". "We are delighted with this publication that reinforces our belief in the potential of Ceflatonin to treat patients with the T315I Bcr-Abl mutation," said Greg Collier, Ph.D., Chief Executive Officer and...University of Manchester researchers reveal clues to new genes behind rheumatoid arthritis
...novel whilst others were known about and have been confirmed by the current study. Professor Worthington and her team have implicated several genes in the development of RA for the first time. Previously two genes were known to explain 50% of genetically determined susceptibility. Now the team have replicat...Major study predicts grim future for Europe's seas
...t in the coming two to three decades. The research confirmed the serious state of decline of Europes regional seas, particularly when the complex web of interactions between different human pressures is taken into account. In each sea, components of the ecosystem were identified that are winners or losers as a...Largest ever study of genetics of common diseases published today
...une diseases, known as PTPN2. The study has also confirmed the importance of a process known as autophagy in the development of Crohn's disease. Autophagy, or "self eating", is responsible for clearing unwanted material, such as bacteria, from within cells. The may be key to the interaction of gut bacteria i...Research team identifies new Alzheimer's gene
...ce, the study included more than 1000 brain donors confirmed to either have Alzheimers disease or be free of the disorder at autopsy. This study resulted in a comprehensive set of high-quality data to be made publicly available to the research community. The researchers believe that deposition of this data set...Finding protection from tumor growth in unexpected places
...esistance of ACE 10/10 mice to melanoma growth was confirmed using several different melanoma cell lines and by using different strains of mice expressing high levels of ACE in macrophages. Interestingly, the small tumors of ACE 10/10 mice contained significantly higher numbers of white blood cells, suggesting...What causes Alzheimer's? Researchers tie beta-amyloids to brain dysfunction
...se of PET imaging, the presence of plaque could be confirmed only during autopsy. "Buildup of beta-amyloid in the brain is thought to be the underlying cause of Alzheimer's disease. Extensive deposits of beta-amyloid are found throughout the brains of all patients with Alzheimer's disease," said Rowe. Resear...PET/CT should be 'first-step' test for patients with Crohn's disease
...ed map of internal anatomy. "Our results must be confirmed by other investigators on a larger scale," said Hustinx, indicating that his team is currently conducting a study evaluating the capacity of PET/CT to assess early on the response of the disease to "biological treatments." Treatment has been signific...Cellular message movement captured on video
...eton. Even without video evidence, scientists have confirmed over the past 10 years that higher organisms use paxillin as a transmitter of locomotion and gene-expression signals from several classes of growth-factor receptors to the nucleus. Cancer researchers are eager to understand paxillins many interacti......ine that can shed membrane from the tips."The team confirmed that myosin-1a is the motor that moves membrane up the microvillus. Brush borders isolated from knockout mice lacking the myosin-1a gene shed membrane at only five percent of the level of brush borders from wild-type animals. The investigators are wo...