Infants needing a heart transplant can accept organs from different blood types
... save lives," says West. "More babies will survive congenital heart defects and go on to live fulfilling lives with a donor heart. We can use this knowledge to decrease the amount of time a patient must wait for a new heart we'll be able to use donor organs more efficiently and perform increasingly successful ...Researchers peer inside embryonic/fetal hearts to discover causes of congenital heart disease
...fetuses who can benefit from intervention to treat congenital defects. Doctor's in the Heart Center at Children's are redefining what has typically been called early detection. With technologically advanced tools including echocardiography they are looking inside fetal hearts and spotting abnormalities months ...PNAS highlights for the week of April 18 - 22
... patients suffering from blindness caused by Leber congenital amaurosis may benefit more than others from gene therapy to restore photoreceptors to the retina....UCLA researchers discover new method to generate human bone
...n more severe cases, such as in children born with congenital anomalies, the new protein may offer an advanced s... Ting, who works frequently with children who have congenital anomalies, began his bone research eight years ago. Wu joined him three years ago, and their collabo...How the environment could be damaging men's reproductive health
...iately after birth and therefore the prevalence of congenital cryptorchidism detected in this study may be a bet...eterm delivery, small gestational weight and other congenital abnormalities of the genitalia. An interesting significant risk factor was the father's weight; babi...Brain chemical serotonin involved in early embryo patterning, Forsyth scientists find
...embryology concerned with abnormal development and congenital malformations). Among other results, the study, which was carried out on frog and chick embryos: Provides the first molecular support for the idea that serotonin is utilized as a large-scale left-right patterning mechanism, thus offering new insigh...WHO centre calls for global action on cleft palate
... that are affordable to developing countries where congenital anomalies will become a priority once the spread of infectious diseases is under control. "Wealthier countries can send specialists out to these countries for short periods of time to perform as many operations as possible but it would be preferable ...JCI table of contents June 1, 2005
...development have been found to cause some cases of congenital heart defects. One such gene is Gata4, mutations ...d in humans, and which have been associated with a congenital heart disease due to muscular defects. In a study appearing online on May 12 in advance of the print...The AIUM celebrates 50 years at the 2005 AIUM Annual convention and preconvention
...urse covers differential diagnoses of anatomic and congenital anomalies. Twelve difficult cases from leading experts in the field will be presented to the audience through images and video clips of each case, along with a set of questions for the audience to answer. After attendees have expressed their opinions...Research marks giant step in potential of using stem cells to treat human disorders
...cord injury and a genetic immune deficiency called congenital hypogammaglobulinemia, which can lead to an increased risk of infections. Using these resources, 11 lines of human embryonic stem cells were derived through nuclear transfer. Somatic cells used from donor patients were grown from skin biopsies. These...Dietary supplement a potential treatment for Canavan disease
...a potential therapy for this devastating and fatal congenital disease, warranting comprehensive clinical trials. This research was conducted by scientists in the Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences in Bethesda, Md. Studies were conducted in collab...From memory formation during sleep to novel components for physics
...s and what role is played by the key mechanisms of congenital immunity. (Spokesperson: Prof. Harald Renz, Philipps University of Marburg) Vascular diseases account, directly or indirectly, for approximately 70 percent of all deaths. These diseases include illnesses such as diabetes, stroke, heart attacks and t...Researchers develop gene therapy to reverse pulmonary arterial hypertension
...oral therapy has already been tried in humans with congenital mitochondrial diseases, the team is initiating a clinical trial in human PAH. Similarly, newer drugs that inhibit Survivin, currently in trials in oncology, might also be directly applicable to PAH patients, Dr. Michelakis explains. The researchers a...MicroRNA tweaks protein that controls early heart development
...ortant to understanding both stem cell biology and congenital heart disease. In order for cells to produce the ...ch team is currently screening human patients with congenital heart disease for mutations in the gene miR-1 to determine what health effects such a mutation might...Researchers track down cause of a disfiguring bone disorder
...s in distant regulatory elements are able to cause congenital abnormalities analogous to coding (gene) mutations." "Human genetic diseases of the skeleton such as sclerosteosis and Van Buchem disease provide a starting point for understanding the modulation of anabolic bone formation," noted team members Michae...Gene mutation responsible for lung and diaphragm defects
... crucial. Birth defects in the diaphragm, such as congenital diaphragmatic hernia (which are about as common as cystic fibrosis), are often fatal. "A lot of people haven't heard of this [disorder] because so many of the kids die early," said Kate Ackerman, Harvard Medical School researcher and lead author of ...Human embryonic stem cells have the potential to develop into eggs and sperm in the laboratory
...ere with human development at this stage and cause congenital abnormalities, infertility and possibly cancer (in particular testicular cancer). By developing suitable tests with embryonic stem cells as they differentiate to germ cells we can investigate the action of these chemicals in the laboratory. "Ultimate...Positive effects of nuclear medicine, 'smart drugs' provide hope for non-hodgkin's lymphoma patients
...ection and disease. A variety of factors including congenital and acquired immunodeficiency states--as well as infectious, physical and chemical agents--have been associated with an increased risk of developing non-Hodgkin's lymphoma. This year, more than 56,000 new cases of non-Hodgkin's lymphoma will be detec...Urine test may help monitor disfiguring birthmarks
... to treat vascular malformations with drugs, since congenital anomalies generally do not respond to drugs," says Steven Fishman, MD, a surgeon on Children's Vascular Anomalies team. "This study gives us hope that with further research we'll be able to develop drug treatments." Fishman is now conducting a Pha......the dilemma faced by parents of children born with congenital central hypoventilation syndrome (CCHS). Afflicting about 250 children in the United States, the genetic disease wreaks havoc in areas of the brain that control involuntary actions such as breathing, fluid regulation and heart function. Now an MRI ...