New therapy for specific form of leukemia
... DNA fragments in the cells of these patients that contain the ABL1 cancer gene. ABL1 also plays an important role in other forms of leukemia. The good news is that ABL1 is counteracted with the drug Glivec, and so this medication can now also provide help to a number of T-ALL patients. T-ALL: T-cell acute l...Commandeering cellular machinery: recognition mechanism to detect small molecules
... grew into visible colonies, suggesting they might contain nuclear receptors for the LG335. To verify that th...then smeared onto another petri plate that did not contain LG335. Any colonies that grew there were discarded. From their initial 380,000 candidates, the res...NIH funds first nationaL SNP genotyping center at Broad Institute
...nstitute Web site, www.broad.mit.edu , which will contain details on the application process later this fall. Stacey Gabriel, Ph.D., the new center's principal investigator and director, currently oversees the Broad's Genetic Analysis platform where she manages all of the genotyping, SNP discovery, and prod...Bugs in the gut could play key role in understanding human disease and drug toxicity
...gram in a normal adult human, and collectively can contain more genes than the host. The combination of interacting genes from the body and gut microbes can be considered a 'super-organism', capable of co-ordinating many physiological and metabolic responses, say the researchers. Professor Jeremy Nicholson, ...Electronics recycling made easy
...Regional General Manager at Onyx. "These items may contain hazardous waste, such as mercury and can contaminate our environment if improperly disposed. Failure to comply with regulations regarding the disposal of these items, puts companies at risk", continued McShane. OnyxPak TM was designed by operations...Story tips from the Department of Energy's Oak Ridge National Laboratory, October 2004
...ystem to shape the plasma and the vacuum vessel to contain it for the National Compact Stellarator Experiment at Princeton Plasma Physics Laboratory. Using complex computer programs and mathematical models, ORNL team members Mike Cole, Paul Fogarty, Paul Goranson, Jim Lyon, Brad Nelson and David Williamson e...Rice engineer wins prestigious Annunzio Award
...d vessels. To promote tissue growth, the scaffolds contain biochemicals that promote cell adhesion, control synthesis of matrix proteins, regulate cell growth and promote the breakdown of the scaffold as new tissue grows around it. Using the latest techniques in genetics and biotechnology, West is designing ...Acoustics meeting in San Diego
... meeting. By the week of October 27, the site will contain lay-language versions of selected meeting papers. These papers will enable you to cover the meeting, even if you can't leave your desk. PRESS LUNCHEON AT MEETING On Tuesday, November 16, ASA will hold a press luncheon, from 11:30 a.m. to 1:30 p....Mitochondria findings may help beat wide range of disease
...prised them because it suggested that mitochondria contain within themselves all the proteins necessary for fusion. This stands in stark contrast to the process of single-membrane fusion, which requires many additional cellular proteins to carry out this important function. "We observed two distinct stages, ...Estrogen protects male rats from aortic aneurysms
... that smooth muscle cells from aortas of male rats contain 2.5 times more destructive MMP-9 protein and 10 times the level of MMP-9 gene expression compared to the same cells from female rat aortas. Known to be involved in AAA formation, MMP-9 is a cell-digesting enzyme that eats away at the wall of the aort...Health, food, new technologies featured during ACS meeting Oct. 17-20 in Peoria, Ill.
...Soda, Halloween candy and other food products that contain high-fructose corn syrup and other sweeteners coul...oods, they say. Dark honey is generally thought to contain higher levels of antioxidants than the lighter varieties, according to the scientists. ( AGFD/AOCS 2...Phillip A. Sharp to present 2004 Ullyot Public Affairs Lecture at Chemical Heritage Foundation
...enes" in mammalian cells. The discovery that genes contain nonsense segments that are edited out by cells in the course of utilizing genetic information is important in understanding the genetic causes of cancer and other diseases. Sharp's research opened an entirely new area in molecular biology and forever...UCLA scientists discover new way to fix defective gene
... Lai and Gatti noted that A-T patients whose cells contain no ATM protein suffer from a severe form of the disease, while patients whose cells hold some ATM protein have a milder form of the disorder. The scientists hypothesized that increasing ATM protein in the cells, even by modest amounts, might allevia...Medical geneticists elected to Institute of Medicine
...onsoring genetics-related Web sites to ensure they contain high-quality information. Prior to joining NHGRI in 1999, Dr. Guttmacher directed the Vermont Regional Genetics Center at the University of Vermont in Burlington, where he launched a series of public health genetics programs. He also had a bus...Consuming fruits and vegetables lowers risk of developing NHL
...ound with NHL in this study, vegetables and fruits contain many other nutrients that may explain the association with NHL. "Dietary modifications such as eating more vegetables and fruits are within the public's grasp to lower their risk of cancer and other diseases. We hope that these find...Mice thrive despite massive genetic makeover
...is, embryonic cells were genetically engineered to contain the newly compact mouse genome. Mice were subsequently generated from these stem cells. The research team then compared the resulting mice with the abridged genome to mice with the full-length version. A variety of features were analyzed, ranging f...ORNL system eliminates perchlorate, helps scientists trace source
...ities of perchlorate from soil or groundwater that contain large quantities of impurities like nitrates and other salt deposits," Gu said. "Our findings show that the ORNL treatment system provides a tool for the identification and forensics of perchlorate contamination in the environment." ORNL has ...International human genome sequencing consortium describes finished human genome sequence
...uired to find regions of the human genome that may contain small and often rare variants involved in disease. "Finished" doesn't mean that the human genome sequence is perfect. There still remain 341 gaps in the finished human genome sequence, in contrast to the 150,000 gaps in the working draft announced ...Babies born after surgery on eggs
...a this week. Mitochondria are unusual because they contain their own DNA, and Tzeng thinks the method works by replacing those with damaged DNA. In eggs, mitochondria have only one copy of this DNA, making them vulnerable to damage as women age. In contrast, mitochondria in the granulosa cells have around f...Single genetic defect links many risk factors for heart disease and stroke
... defects in a vast array of proteins that normally contain isoleucine, thereby contributing to a broad range of cellular malfunctions. Once the researchers determined that a mitochondrial defect caused the diverse traits, they reexamined the family members for other problems known to be linked to mitochondr...