Talented sniffer: A receptor known for guiding sperm to egg plays a role in the nose
...roductive functions or acts bi-functionally in the context of conventional olfaction has been a longstanding question. In their current study, a team of researchers including Marc Spehr of the University of Maryland and Katlen Schwane of Ruhr-University Bochum, Germany, addressed this question by using a ...Putting physiology into the Nobel Prize: 2004 marks 100th anniversary of Pavlov's award
...r like Axel and Buck's work, research in the broad context of the health sciences, of which physiology is arguably the most inclusive. [A comprehensive review article on smell, "Olfaction: From odorant molecules to the olfactory cortex," appeared News in Physiological Science (NIPS, see below), June 2004, by...Researchers find chemosignal that encourages women's sexual desire
...hers much show that the substances operate "in the context of normal daily interactions with breastfeeding women and their infants. Ideally, such a study would also demonstrate how these effects would have increased the evolutionary fitness of individuals who used this system of social communication during h...Acoustics meeting in San Diego
...h. People use laughter to express a happy or funny context or to render a positive response in conversation. Similarly, this technique aims to make the expression of laughter in computer-generated speech more effective and natural. (1aSC11) CLASSROOM ACOUSTICS: REAL-WORLD IMPLEMENTATION Crucial for a pr...Research gaining momentum by silencing genes
...he study of Arabidopsis genes a lot easier. In the context of the AGRIKOLA European project, they are working on a collection of 'inactivating' fragments for all Arabidopsis genes. The current collection contains fragments designed to inactivate more than 20,000 different genes. This project will accelerate ...Gene-altered mouse is model for rare autoimmune syndrome
...he immune system and autoimmunity occurring in the context of only a single genetic lesion." Versnel is at Erasmus Medical Center in the Netherlands. According to Zhuang, while Sjgren's syndrome is not well known, affecting up to 0.6 percent of the population. It manifests itself in middle age, mostly in ...Soaking up signal: Endocytosis controls spreading and effective signaling range of Fgf8 protein
...eted signaling proteins that they encounter in the context of their extracellular environment. The finding is important because cells in developing tissues are extremely sensitive to such protein signals, and thus the range of these signals within a given tissue must be precisely regulated to prevent morphol...Sandbagging cancer in the bloodstream
...reatment strategy would have to be explored in the context of clinical trials before doctors knew for sure if it would work in humans, and these may take several years....JCI table of contents November 1, 2004
...n accompanying commentary places this study in the context of the function of the ABCA1 transporter and its impact on HDL production along with studies of the genetics and molecular mechanisms relating to Tangier disease. TITLE: Genetic variation in ABC transporter A1 contributes to HDL cholesterol in the ge...Mutations in transporter protein effect HDL levels in the general population
...n accompanying commentary places this study in the context of the function of the ABCA1 transporter and its impact on HDL production along with studies of the genetics and molecular mechanisms relating to Tangier disease....Genetic variant linked to weakened heart pumping
...bolism. Most of these studies, however, are in the context of diabetes. The Duke team found that a particular variant of PPAR, a polymorphism called PPAR-I7, is associated with reduced function of the left ventricle. If additional studies confirm this association between PPAR-I7 and the weakening of the hea...In a tiny squid, bacterial toxin governs organ development
...e either good or bad - depending on its biological context - promises to rattle long-held perceptions of micr...g author of the Science paper. "It is all context dependent," says McFall-Ngai. "It has to be that we have mechanisms to use these molecules in differ...Chimpanzee brains are asymmetrical in key areas and their handedness reflects it
...symmetry. This fact, especially if studied in the context of functional behaviors that reflect asymmetries, may help scientists get a better fix on the evolution of the limbic system in all primates, including humans. Says Hopkins, "The limbic system asymmetries advance the position that asymmetries ar...NASA study finds tiny particles in air may influence carbon sinks
...t regular intervals to provide broader geophysical context to the more continuous data available from AERONET. MODIS data were also used to assess the vegetation health and map leaf area for each site, and to interpret the net ecosystem exchange. For each site, the researchers analyzed how carbon cycled in e...Ocean colour satellites guide research ship through South Pacific's watery desert
...mposites were produced by France-based ACRI in the context of Coastwatch, an ESA-supported information service for coastal environments (part of the Global Monitoring for Environment and Security - GMES - Services Element). BIOSOPE involved studying the biological contents of water u......cer from Iceland's National Cancer Registry in the context of deCODE's nationwide genealogy database. This enabled Dr. Amundadottir and her team to establish how often cancers occurred in first through fifth degree relatives of some 32,000 cancer patients over the past 50 years. For 16 of the 27 cancers s...MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks
...cal researchers." Moleculizer was developed in the context of MSI's "Alpha Project", an ambitious experimental and computational effort to understand the quantitative behavior of a cell signaling pathway in yeast. The Alpha Project is funded by the National Institutes of Health's National Human Genome Resear...Combination therapy boosts effectiveness of telomere-directed cancer cell death
...omere-directed molecular cancer therapeutics" The context and implications of this work are discussed in a Preview by Shay et al. The other members of the research team include Yukiko Muramatsu of the Japanese Foundation for Cancer Research in Tokyo; and Tomokazu Ohishi and Takashi Tsuruo of the Japanese Fo...Blood test shows promise as monitor for antiangiogenic cancer therapy
...surrogate marker analysis of antiangiogenesis" The context and implications of this work are discussed in a Preview by Schneider et al....Study in Royal Society journal on managing GM crops for environmental benefit
...bility analysis for solitary waves is developed in context of the Hamiltonian system of coupled nonlinear Schrdinger equations. The linear eigenvalue problem for a non-self-adjoint operator is studied with two self-adjoint matrix Schrdinger operators. Sharp bounds on the number and type of unstable eigenvalu...