Scientists solve the mystery of how Botox attacks nerves and eliminates wrinkles
...ospasm), lazy eye (strabismus), involuntary muscle contractions in the neck (cervical dystonia) and acute underarm sweating (severe primary axillary hyperhidrosis). Botox users might be surprised to learn that they're actually receiving minute injections of a bacterial neurotoxin called botulinum, one of the most...Femtosecond laser technique opens new opportunities for research on neural regeneration
...e contracting. It functions during the alternating contractions of muscles on either side of the body that enable the worm to wiggle backward with a smooth wavelike motion. Hulusi Cinar and Jin have been studying so-called "shrinker" mutants that lack this ability due to a genetic defect. "A normal worm, when you...Powerful X-ray beams at Argonne, new electronic flight simulator
... of molecules responsible for generating the rapid contractions of the muscle with a resolution of 6/10,0000th of a second. The flight simulator, which fools a tethered fly into "thinking" it is flying freely through the air, is necessary to produce a stable pattern of wing motion and enabled the researchers to c...Plant protein mimics hormone that mitigates diabetes and obesity
...the hormone oxytocin binds to cells in the uterus, contractions - and childbirth - begin. When bound to its receptor, adiponectin regulates sugar uptake and, in mouse models, prevents the development of diabetes and atherosclerosis, or the hardening of the arteries associated with heart disease. Previous studies ...Regular exercise helps protect muscles in elderly from soreness, injury
...rticularly damaging to sarcomeres. And lengthening contractions are some of the most common type of contractions humans do leg muscles contract and lengthen as we sit down or walk and run, and arm muscles contrac...Estrogen, SERMS reduce asthma impact by halting constriction
.... Carbachol is often used to stimulate, or mimic, contractions of airway and other muscles. The Georgia researche...tter acetylcholine traditionally used to stimulate contractions of airway and other muscle. Each ring was exposed to a range of carbachol concentrations and the mag...Cancer drug could aid premature labour
... produce a muscle relaxant, which in turn prevents contractions and keeps the uterus in a relaxed state. It is kn... that decreases in hCG receptor levels may lead to contractions in the womb and labour. Women whose babies are born prematurely experience an acute drop in the num...Tetanus toxin found to have therapeutic properties
...apy to treat disorders caused by abnormal muscular contractions such as strabismus, cerebral palsy, anal contractions and torticollis. Recently these toxins have been used even in cosmetics against wrinkles. For these ...APS oxytocin/vasopressin conference: 13 highlighted presentations
... GSK nonpeptide oxytocin receptor antagonists damp contractions in late-term rat pregnancy "Delaying labor with a...ported that these compounds suppressed spontaneous contractions in late-term pregnant rats. Short gestation/low birth weight is the second-leading cause of infant d...GSK nonpeptide oxytocin receptor antagonists damp contractions in late-term rat pregnancy
...portant role in pre-term labor, especially causing contractions of the myometrial muscles. OT receptor antagonists inhibit spontaneous myometrial contractions in vitro and suppress myometrial activity in live animal models. In a clinical trial, the mixed OT-v...OT, VP studied as novel psychiatric drug sources; consider gender-specific drug models
...olecule, was developed and commonly used to induce contractions during birth. Similarly, vasopressin receptors in the kidney and vascular smooth muscle have been targeted for the treatment of heart failure and other diseases. Drug companies, however, may have "underappreciated the important roles that both the c...Researchers reveal secret of key protein in brain and heart function
...believed to play a role in everything from cardiac contractions to memory creation. Results are published in The Journal of Biological Chemistry. Dale Mierke, associate professor of medical science at Brown, said that knowing how a piece of SAP97 is built is an important step. Now that part of the protein's struc...Spiders help scientists discover how muscles relax
...type of muscle that controls skeletal movement and contractions of the heart. Striated muscles are made of long cylindrical cells called muscle fibers. Within the fibers, millions of units known as sarcomeres give rise to movement of skeletal muscles. Sarcomeres are composed mainly of thick filaments of myosin, t...Scientists develop 'clever' artificial hand
...a small processing unit and is controlled by small contractions of the muscles which move the wrist. Dr Chappell said: "With this hand you can clutch objects such as a ball, you can move the thumb out to one side and grip objects with the index finger in the way you do when opening a lock with a key, and you can......study showed that the gene controlled the rhythmic contractions of smooth muscle in three parts of the worm's body...emale and make their own sperm and eggs. Rhythmic contractions control how the eggs are pushed down the tube-like gonadal sheath and into the spermatheca, which co...Cyberkinetics, Case to develop system to help restore extremity function
...l current to restore movement by initiating muscle contractions in paralyzed extremities. The main components of an FES system are the electrodes, the stimulator, and sensors or switches. When FES is being used to move muscles, current pulses in the electrodes cause the weakened or paralyzed muscles to contract...Radical approach to cardiac resynchronization shows promise
Correcting the timing of heart contractions through cardiac resynchronization therapy can be a lifesaver for people with advanced heart failure. But the procedure, as it is done today, fails in about 15 percent of patients. Using a minimally invasive approach that may startle heart specialists...Soy diet worsens heart disease in mice, says University of Colorado at Boulder study
...ber enlarges, the heart wall thins and the pumping contractions of the heart are impaired, leading to heart failure, she said. HCM is the leading cause of death in young athletes and affects about one in 500 people, although milder forms of the disease often go undiagnosed, said Leinwand. To date, 18 genes asso...Inflammatory reaction drives hormone resistance in cancer, study suggests
...ductive processes, such as the induction of muscle contractions characteristic of labor, Parker added. The process may therefore have important implications for understanding reproductive disorders, such as preterm labor, he suggested. "Preterm labor is now widely considered to be an inflammatory disease that acc......llez. "Botulinum toxin could lead to inhibition of contractions of tumor vessels, improve tumor perfusion and oxyg...tic nervous system, it could prevent neuromuscular contractions of vessels in tumors. The inhibition of this contraction could literally open the gate to improved t...