Tag: "copies" at biology news
Random gene expression may drive HIV into hiding
... it to proliferate into many genetically identical copies
of itself, he found that these progeny did not all show the same behavior: some turned their viral expression on high and others turned it off. This dichotomy in cell fate from genetically identical cells is consistent with the idea that random fluct...
Gene silencing technique offers new strategy for treating, curing disease
..., but first is copied by special enzymes into many copies
of messenger RNA, which then move out of the nucle...A once it's already produced. But blocking all the copies
of messenger RNA before they can make a protein within a cell is akin to using a bucket to catch all...
Building a better mouse model of lung cancer: FHIT counts
...hen mutations or alterations eliminate one or both copies
of the FHIT gene, the "brakes" that control cell g...ished a control group of normal mice that had both copies
of the gene. They exposed all the mice to NNK, a powerful carcinogen commonly found in tobacco smok...
New theory tests sex ratios under asymmetrical local mate competition among parasitoid wasps
...ghters, may mean a female does not pass on as many copies
of her genes to the next generation as another mother. The crucial determinant of sex ratio for many species will be how likely related individuals will interact, in particular whether brothers will be competing amongst themselves to mate with their ...
The AIUM releases new statement regarding keepsake imaging
...s other than those of providing patients images or copies
of their medical records at cost may violate the principles of medical ethics of the American Medical Association (E-8.0621 and E-8.0632) and the American College of Obstetricians and Gynecologists.3 The AIUM therefore reaffirms the Prudent Use State...
Evolution of life on Earth may hold key to finding life in outer space
...lular protein synthesis is the process whereby RNA copies
genetic information from DNA and translates it into proteins that are essential to the structure and function of all living cells and viruses and play a role in immune response. Fox and his group are examining the various components of the ribosome ...
Gene loss accelerates aging
...etic technique that enabled them to eliminate both copies
of the gene from particular tissues--including skin and other multi-layered epithelial tissues--after the animals reached maturity. The effects of premature aging observed in these p63 deficient mice (image available on request) were hair loss, reduc...
New gene associated with Fanconi anemia 'explains' hallmark chromosomal instability
...ic disease, an affected child needs to inherit two copies
of an errant gene, each from a parent that carried... other words, the five patients each inherited two copies
of the same mutation, one from each parent. When the researchers looked at the other families in the...
Analysis of flower genes reveals the fate of an ancient gene duplication
...se they effectively allow at least one of the gene copies
to evolve while the (likely important) function of the original gene can remain intact. In this way, the duplication of pre-existing genetic information provides the raw material from which new gene functions can evolve, thereby contributing to the e...
Solving the mystery of mutated proteins and the brain
...y form of the disease. In families that have extra copies
of the normal gene, the toxic effects of high prot...s of Alzheimer's disease," she said. "Three normal copies
of amyloid precursor protein can cause the enhanced levels of the protein and its byproduct that are...
Pinpointing the cause of a neurodegenerative disorder
...generative disorders can be caused by having extra copies
of a normal protein, not just a mutated one. Peopl...e in neurodegenerative disorders that having extra copies
of a normal protein, not just a mutated one, can cause pathology. There have been observations that ...
Big differences in duplicated DNA distinguish chimp and human genomes
...arts of those duplicated segments have only single copies
in the chimp genome, and it is possible that the c...red segmental duplications, humans often had fewer copies
of those segments than chimps. The most dramatic example involved a piece of DNA near the site of an...
A new view of human-chimpanzee genome differences
...ionarily important because they give rise to extra copies
of genes that allow evolution to more freely "expe...n than humans, but they did have a great number of copies
of the duplicated segments. Of particular interest to the scientists, was that a few of the shared d...
Human Y chromosome preserves itself better than the chimp Y
...defend itself because it carries spares -- back-up copies
-- of these testis-expressing genes." As part of the mating game, chimpanzees make much more sperm than humans do, so their testes need to be operating at high capacity. As a result of the newest research, Page added, "we can also draw some inference...
Mouse genome much more complex than expected
...a is copied (rewritten or 'transcribed'). Only the copies
can leave the cell nucleus. They consist of a DNA-...y tried to find the 'original sources' of the mRNA copies
in the DNA encyclopedia: information and nonsense are apparently not distributed randomly. Instead t...
Embryonic stem cells accrue genetic changes
...rparts -- displayed gross changes in the number of copies
of chromosomes or parts of chromosomes, in the mar...xtra copies. Depending on the gene affected, extra copies
could lead to accelerated cell growth, increased cell death, or no measurable effect at all. In ad...
New study to explore cellular circuitry
...archers created a library of 6000 clones, or exact copies
of the genes of the yeast cell, one clone for each known protein present in the cell. What makes the set of clones useful is that each one manufactures large amounts of a single protein with a "tag" attached. One common application of the library i...
Blood test for colon cancer risk to be goal of Hopkins project
...ive percent to 10 percent of people, however, both copies
of the gene are turned on -- a problem called loss of imprinting. To check for loss of imprinting in people, the researchers will be looking for small methyl groups that should be attached to the DNA near the IGF-2 gene in blood cells from study par...
Rare eye-movement disorder may shed light on brain and cardiovascular development
...he head, face, and brainstem. Mice that lack both copies
of HOXA1 universally die. Until this study, no hum...science, have found living people with two mutated copies
of HOXA1 -- from three different parts of the world. "This is the first description of a human syndr...
Gladstone Institutes assists with Exploratorium stem cell exhibit
...any others: they can simultaneously make identical copies
of themselves and make differentiated--or specialized--cells, such as cardiac myocytes. At the exhibit, visitors view the development of cardiac myocytes, the cells that form the heart. Thus they can witness the transition of stem cells from their un...
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