Researchers provide road map for generating B cells from stem cells
...g a multi-potent progenitor cell -- stage 1, which could become any type of blood cell -- toward becoming a lymphoid progenitor, stage 2. They trigger the expression of certain receptors on the cell surface, such as Flk2 followed by IL-7R, which are necessary for receiving subsequent external signals. In ...New method identifies chromosome changes in malignant cells
..., statistics and biology," she said. "Neither side could do it alone." Their findings will be published in ...d amplifications very accurately." The new method could be particularly important for cancer research because it gives scientists a clearer idea of what is ...UF scientists have bionanotechnology recipe to find elusive bacteria
...biosensors that, once implanted in the human body, could perform a number of medical duties, from deliverin...a possible bioterrorist agent by traditional means could take days and would involve sealing off the entire area during that time, he said. "Instead, we can ...Rice engineer wins prestigious Annunzio Award
... materials for small-diameter vascular grafts that could eliminate the need for doctors to use veins from a patient's leg for heart bypass surgery. West is developing techniques to use a patient's own cells to grow replacement blood vessels in the lab -- blood vessels that can be used in procedures like c...Acoustics meeting in San Diego
...hat suggest even modest levels of underwater sound could trigger bubble formation in a liquid of supersatur...s can result in very large nitrogen bubbles, which could have potentially deleterious biological effects. Crum will present preliminary results of these exp...New study on smallpox in monkeys reveals tactics of a killer
...t this new knowledge of how smallpox acts on cells could speed up development of smallpox countermeasures. ...olecular workings similar to smallpox, researchers could test countermeasures on it in a greater number of lab facilities, hastening the pace of research. ...Rutgers-led research offers new clues in the genetic mysteries of maize
...ound that as much as 22 percent of the maize genes could be identified as being different. This was surprising, considering that other close relatives such as chimpanzees and humans differ in less than one percent of their genes. "It looks like significant evolutionary change happened in a relatively s...Estrogen protects male rats from aortic aneurysms
...ng exactly what triggers them and how they develop could lead to an effective therapy someday. It also could help us identify people with a high risk of AAA formation who need regular diagnostic testing." Scie...Study in Royal Society journals presents evidence for inherited factors in homosexuality
...population. The authors here argue genetic factors could partially explain male homosexuality, and propose ...: genetic factors favouring homosexuality in males could increase fecundity in females, recovering the loss of fitness. They suggest these factors should be ...Technique for genetically modifying blood stem cells brings cure for blood diseases closer
...ssible that the sudden introduction of beta-globin could trigger an immune response against this protein. ...o the cell; red cells derived from transduced HSCs could then make significant amounts of HbF. This vector did not consistently produce high levels of gamma-...Health, food, new technologies featured during ACS meeting Oct. 17-20 in Peoria, Ill.
...tain high-fructose corn syrup and other sweeteners could one day get a fresh makeover using honey, researchers say. Scientists at the University of Illinois in Urbana say the ancient sweetener may be a healthier alternative than corn syrup due to its higher level of antioxidants, compounds which are believ...Touching research: How white blood cells navigate
...cts. Engineers are already working on devices that could filter out harmful cells by making them stick, and devices that capture rare but crucial cells such as stem cells and then release them as needed. The team brings a unique engineering viewpoint to a domain the human body that is often governed by ...Channel protein converts vibrations to electrical signal
...oelectrode on the mouse hair cells, the scientists could directly measure the amount of current flowing thr...s amplify different frequencies, so this mechanism could create the sharp tuning in the ear that allows us to discriminate fine differences in pitch. If this...Gladstone researchers resolve key Huntington's disease mystery in Nature cover story
...ith powerful techniques of statistical analysis -- could also be used in studies of other neurodegenerative...s is the most widely known. Moreover, the approach could be used to measure the nature and magnitude of the relationship between any two biological events wi...Study using robotic microscope shows how mutant Huntington's protein affects neurons
...s Dr. Finkbeiner. The automated microscope system could be applied to sort out many important questions about how cellular changes or abnormalities affect disease, he adds. He and his colleagues are now planning studies to examine the role of proteasomes enzyme-filled compartments that break down and re...Where in the brain decisions are made
...op rigorous laboratory behavioral experiments that could pinpoint those areas. Now, Paul Glimcher and colle...r a certain monetary reward or a risky choice that could yield a larger reward. An opponent, meanwhile, was asked to select an option that would prevent the ...Award-winning INEEL probe to help safely monitor hazardous waste sites
... through all the possible problems and things that could go wrong. Then we designed the flaws out from the start." Faced with a 1960s-era nuclear waste site that they needed to sample directly, Jones and his team set about in 1999 to build new tools for the cleanup job. They wanted to collect data from dee...INEEL uses extremophile bacteria to ease bleaching's environmental cost
... Park's hot springs lives a type of bacterium that could help make industrial bleaching cheaper and more en...Large-scale production of the T. brockianus enzyme could end decades of environmental costs from industrial bleaching. Chlorine, used for more than a century...Tips from the Journals of the American Society for Microbiology
Drug/DNA combination could offer longer-lasting more efficient flu vaccine ...e drug tucaresol to plasmid DNA influenza vaccines could offer longer-lasting and more efficient protection against the influenza virus. The findings appear......s, the findings suggest that such inhibiting drugs could be used to treat and prevent Alzheimer's disease (AD). CP-113,818 mimics a cholesterol molecule that the enzyme, called "acyl-coenzyme A: cholesterol acyltransferase" (ACAT), converts into a form of cholesterol that the cell stores in droplets. When ...