ASU gets grant to develop high speed DNA sequence reader
... methods. If successful, Williams said the project could lead to relatively cheap machines that can read the genome for use in research, and it could possibly bring the technology to the brink of clinical use. Williams will be working with Sergei Aks...Research to explore revolutionary gene sequencing: Threading the molecular needle
...State University and Professor of Physics at ASU, could make the long-dreamt-of era of true genetic medici...erent DNA bases with the ring. The resulting data could thus be translated into the precise sequence of the DNA molecule. To thread the DNA th...Scientists closing in on nerve proteins' contributions to memory and hearing loss
...arious zinc-finger proteins that they already knew could increase the activity of PSD-95. After this study and additional testing, they determined that Eos, a recently identified zinc finger protein, was Ngr-ICD's most likely partner. In its normal role, PSD-95 provides a support structure for recept...VYTORIN (TM) superior again to Lipitor at lowering LDL (bad) cholesterol
...uld be reported to a doctor promptly because these could be signs of a serious side effect. VYTORIN should be discontinued if myopathy is diagnosed or suspected. To help avoid serious side effects, patients should talk to their doctor about medicine or food they should avoid while taking VYTORIN. In thr...'Broken' gene reveals evolution of salt retention and possible ties to hypertension
...and that advantage increases with latitude." "This could change the way we look for disease genes," she added. "Historically, we have searched for mutations, altered or damaged versions of genes that cause rare disorders, like cystic fibrosis or phenylketonuria. Now, we are starting to look for common ge...Stress impairs thinking via mania-linked enzyme
...function." "In the future, drugs that inhibit PKC could become the preferred emergency room treatments for...s, namely in the PKC pathway. Since PKC inhibitors could act more directly, they might quench symptoms more quickly. Patients could carry PKC inhibitors and ...Gimli gobblers Mercury scientists to conduct unique human experiment next week
... Lucotte. That something, the researchers suspect, could be simply old fashioned tea. Tea-drinking Japanese...h the important scientific evidence the experiment could reveal, Dr. Lucotte says that the Gimli tea-and-fish experiment is a crucial part of grounding the r...Wistar study demonstrates heritability of non-genomic information
...r to target its designated promoter, the insulator could then be removed from the system without effect: Wi...that traits acquired by parents during their lives could be passed on to their offspring. Lamarck's ideas about evolutionary process were overtaken in subseq...Gene found to defend against environmental pollutants and pulmonary emphysema
...tanding of the human body's defense mechanisms and could lead to the identification of what factors make some people more susceptible to lung diseases. The article is published in the current issue of The Journal of Clinical Investigation. The so-called "master gene"--nuclear factor erythroid-derived 2-rel...Gut microbes can open gates in fat cells
...n, this research suggests that derivatives of Fiaf could potentially become therapeutic agents. "We uncovered the importance of Fiaf by studying mice raised without ever being exposed to microorganisms. These so-called germ-free mice eat 30 percent more than normal mice yet have 50 percent less body fat,"...Bristol scientists find key to unlock body's own cancer defence
...F works, and its effects on tumours, means that it could be possible to prevent tumour growth by starving the tumour using the body's own anti-cancer agent, VEGF165b. The advantage of using VEGF165b over established compounds to treat cancer is that VEGF165b is a natural protein produced by the body under......t spherical. But in some of the best specimens, we could see that the tube branches and has cross-walls," Xiao said. "But can it be linked to the embryos?" Upon examination of more embryos collected from the original site, Xiao's research team has discovered some embryos that may be at the hatching stage. ...Safety and immunogenicity data available for new pertussis booster vaccine candidate for adolescents
... alternative for the routine adolescent Td booster could offer important protection against pertussis, as well as diphtheria and tetanus, without an additional injection or doctor's office visit." Study Findings In this observer-blinded, randomized, controlled, multi-center clinical trial, 4,114 healthy ...JCI table of contents November 1, 2004
...c nature. One class of proteins called semaphorins could play a role in the development of tumor metastasis as they have been shown to block the migration of some cell types in culture. Michael Klagsbrun and colleagues, from Harvard Medical School, examined semaphorin 3F (SEMA3F) expression in human metast...Sleeping, waking, ... and glucose homeostasis
...utant mice. Furthermore, whereas the normal mice could fairly easily return their glucose levels to norma... besides what we eat, our internal circadian clock could also be an important regulator of blood sugar levels. What is still left to be explored is whether ...Stem Cells: Saving Lives or Crossing Lines?
...an embryonic stem cell research, the United States could for the first time in modern history lose its leadership role in biomedical research," said Neal Lane, university professor at Rice and senior fellow in science and technology at Rice's Baker Institute for Public Policy. "We're bringing together ex...Loyola begins study on blood substitute in trauma patients at the scene of injury
...blood substitute works the way we hope it will, it could be the first major advance since the introduction ...ubstitute into our patients at the scene of injury could increase their chance of survival," said Gamelli. "Right now, one in five Americans die of trauma-r...Scientists raise concerns about second wave of 'mad cow' prion infection
.... Eglin said the current decline in reported cases could be followed by a new wave of vCJD infections around the world of unknown magnitude. These concerns were echoed by the panelists, who noted the increase of vCJD in France from six to eight cases in just the past few months and the news that blood from...Other highlights in the November 3 JNCI
...olizes the drug midazolam combined with genotyping could help to optimize irinotecan chemotherapy, accordin...ombining CYP3A4 phenotyping with UGT1A1 genotyping could assist with the optimization of irinotecan chemotherapy. The method is currently undergoing validati......researchers have a ready source of cells that they could manipulate genetically, explained the study's seni...thor, Ralph Brinster. For example, researchers could implant a new gene into a spermatogonial cell, reproduce a large number of spermatogonial cells in t...