Study provides insight into cellular defenses against genetic mutation
...post-doctoral associate Nao Hosoda, Ph.D. "That is critically significant because, knowing the structure and role of CBP80, we can now seek to develop drug-based gene therapies that interfere with it in cases where NMD contributes to disease-causing protein shortages." Researchers may be able to convert mRNA qu...Wild birds help to create human flu vaccine
...spread of avian flu. Wild birds, some of which are critically threatened or endangered are also being impacted directly by the H5N1 strain of influenza virus. Focusing resources on the hubs and activities where humans, livestock, and wildlife come into close contact is the best hope for successfully preventing...Avian flu in perspective: New England Journal article reviews 'spectacular' findings
...ould emerge," Belshe says. "This research provides critically important insight into the origin of pandemic influenza." Both mechanisms described in the articles were observed during worldwide pandemics of the 20th century. Scientists now conclude that the prospect of a new worldwide pandemic during the 21st ce...'Go Fishing' no game for inland waters worldwide
...re Organization, according to the paper. Among the critically endangered fish cited in case studies by the team ...re Organization, according to the paper. Among the critically endangered fish cited in case studies by the team are the Mekong giant catfish of the Mekong River b...Zeroing in on progeria: How mutant lamins cause premature aging
...he organization of regions of chromosomes that are critically important in regulating gene expression. These so-called heterochromatic regions include the inactive X (Xi) chromosome found in normal female cells. One of the hallmarks of Xi heterochromatin is its association with proteins known as methylated hist...New enhancements upgrade NIST Mass Spectra Library
... than 163,000. Each spectrum has been analyzed and critically evaluated to ensure that the library has the best possible current data. The upgraded library also includes two important new classes of chemical reference data. Gas-phase "retention index" data--used in gas chromatography to identify volatile organi...Underwater listening devices yield discoveries about endangered large whales
... thought to migrate to midlatitudes in winter. And critically endangered North Pacific right whales have been detected acoustically in locations where they were formerly abundant but have not been seen in decades. The results from acoustic whale surveys conducted to date could pave the way for more sophisticat......n Africa and in some protected areas elsewhere, to critically endangered in vast regions of central Africa," says Douglas-Hamilton, who helped bring about a global ivory trade ban after chronicling the massacre of elephants in the 1980s. "Since they need space to roam and since the human population is increasi...USC scientists link variations in growth-factor gene to risk of prostate cancer
...ogic effect," the researchers observed. "Our study critically evaluates the possibility of false positive results, and important issue faced by genetic association studies, and provides strong support for the involvement of the IGF pathway in the development of prostate cancer," Cheng noted. "By identifying the...Public support for environmental protection on the decline
...s that environmental protection and management are critically important to public health, job creation and economic development, he said. He stressed the importance of such efforts because the former champions of the policy non-Hispanic white, middle-class, college-educated and suburban residents are now the ...Keeping biological tubes in check: New insights into tube size morphogenesis
...neys, lungs, and vessels of the vascular system is critically dependent on the length and diameter of the tubular branches of which they are composed. Several devastating pathological conditions like polycystic kidney disease and ischemias have been intimately linked to the aberrant sizes of tubular organs. Yet...Vaccine provides 100 percent protection against avian flu virus in animal study
...accines, their adenovirus-based vaccine could be a critically important complement to them. Because it appears to be so successful in immunizing chickens against H5N1, widespread inoculation of susceptible poultry populations could provide a significant barrier to the spread of the virus via that route in this ...Wide range of topics covered by new research units
...n progressively deprived of magic or myths will be critically examined, since the construction of modern origins has always been used in the context of strategies of justification and legitimisation. The investigation of the corresponding links, conceptual models and narratives will be studied for the last thre...Arctic marine mammals: The new canaries?
.... "Understanding contaminants in marine mammals is critically important to addressing oceans and human health in Alaska," said O'Hara, who will be presenting a seminar titled, "Biomagnification and pathways of contaminants in Arctic food webs" and will participate in the press briefing, "Marine mammals: The new...Scientists discuss evolutionary roots of social behavior
...has monitored a population of Northern muriquis, a critically endangered primate from Brazil. Based on her observations, Strier knows that muriquis spend less than three percent of their time involved in direct social interactions, and more than 60 percent of their time near other individuals in their groups. ...Newly identified mechanism helps explain why people of African descent are more vulnerable to TB
...on with certain pathogens and that turns out to be critically dependent on vitamin D. This description provides a different way to think about how human immune systems battle pathogens in general. The research team found that when Toll-like receptors in humans are stimulated by specific molecules of the tuberc...Cancer virus protein needed for successful infection
...t to be unimportant for its replication is in fact critically needed by the virus to initiate an infection and to reproduce. The study examined the human T lymphotropic virus type 1 (HTLV-1) and a protein it makes called p13. The protein is one of the virus' so-called accessory proteins, proteins that earlier ...Enzyme crystal structure reveals 'unexpected' genome repair functions
...10,000 DNA bases are repaired each day, making NER critically important for cell survival and protection against mutations. NER is a critical defense mechanism that removes DNA lesions caused by the mutating effects of sunlight (ultraviolet light) and toxic chemicals. In addition, NER is critical to the succes...Avelox as effective as Levofloxacin combination therapy for severe community-acquired pneumonia
...t the University of Barcelona in Spain. "CAP can critically affect older patients who may be struggling with existing conditions such as heart disease and diabetes," he added. "These results provide additional evidence that AVELOX is a safe and effective treatment for patients with CAP." CAP affects approxim...Interdisciplinary team develops guidelines for treating severely injured patients
...roject helps physicians tailor treatments for each critically injured patient." While the inflammation glue grant focuses on the care of patients once at the hospital, a complementary NIH program, the Resuscitation Outcomes Consortium, aims to improve patient survival before an injured person reaches the emerg...