T cell's memory may offer long-term immunity to leishmaniasis
... each year the world sees 1.5 million new cases of cutaneous leishmaniasis, which infects the skin, causing scarring boils, and 500,000 new cases of visceral leishmaniasis, which infects internal organs, causing death if left untreated. Particularly vexing to researchers has been the f...JCI table of contents, November 15 2004
...ARY: TITLE: Piecing together the puzzle of cutaneous mosaicism. AUTHOR CONTACT: Amy S. Paller Department of Dermatology. Northwestern University, Chicago, Illinois, USA. Phone: 312-695-0197; Fax: 312-695-0664; E-mail: apaller@northwestern.edu . View the PDF of this comme...Desert plant may help treat insidious tropical diseases
...ldiers stationed in the Middle East have developed cutaneous leishmaniasis. "At last count, about 700 of our soldiers had the disease," Werbovetz said. "It's not an illness that people die from, and the troops can still perform their duties. But it does leave scars and can also make a person prone to infection...Readers of genome decipher signatures of cancer patient outcomes
... targets specific to this form of skin cancer. "In cutaneous melanomas, no active adjuvant therapy has been fully demonstrated so far," Spatz said. "The identification of new potential therapeutic targets is crucial and overcomes the importance of prognostication methods. "Some of the genes in our signature b...Anthrax stops body from fighting back, study shows
...n, Southwick said. Twelve other people contracted cutaneous (skin) anthrax infections, which are not usually fatal. Knowledge about anthrax and how it works has improved since then, too, Hanna said. Now doctors know what anthrax looks like and what publichealth steps to take, he added. The next step for UF re...Other highlights in the September 21 JNCI
... potential location of a gene involved in familial cutaneous malignant melanoma and ocular malignant melanoma, ...uthors also examined tumor tissue from 10 sporadic cutaneous malignant melanoma lesions for expression of RASEF, a known gene in this region. Expression was foun...Researchers use 'trickery' to create immune response against melanoma
...r-related deaths. Lymphomas of the skin, including cutaneous T-cell lymphomas, are diagnosed in approximately 16,000 to 20,000 people in the United States each year and are often difficult to diagnose in early stages....Ultraviolet B light exposure associated with increased risk of skin cancer
...the less common and potentially lethal skin cancer cutaneous malignant melanoma. UV-B radiation can cause strands of DNA to break in sun-exposed skin or skin cells. People with a condition called xeroderma pigmentosum are at a very high risk of sunlight-induced skin cancer because their cells are unable to rep...JCI table of contents: September 7, 2006
... TITLE: Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion AUTHOR CONTACT: Gunnar Nilsson Karolinska Institute, Stockholm, Sweden. Phone: +46-8-517-70205; Fax: 46-8-335724; E-mail: Gunnar.P.Nilsson@ki.se . Katarina Sternudd Press Of...Tips from the Journals of the American Society for Microbiology
...cs have shown to be 100% effective at treating the cutaneous form of anthrax, however inhalation anthrax has a fatality rate of 75% or higher even with antibiotic treatment. The vaccine currently available is administered intramuscularly (i.m.), but recent studies suggest that intradermal (i.d.) delivery (in ...Genetic analyis for personalizing of treatment of lung and colon cancer, certain sarcomas
...f the toxicity - fatigue, digestive indisposition, cutaneous reaction, diarrhoea, vomiting, as well as alterations in the liver and kidney. In this way the patient will have a better quality of life. A number of research projects undertaken by different teams have confirmed the use of these markers for resp...... in 2005 for L. major, which causes a less severe, cutaneous form of the disease. Despite the major differences in disease type, only 200 out of more than 8000 genes present in each genome were found to be differentially distributed between the three species. This exceptionally small variation in gene content ...