Early environmental exposure may accelerate age-related neurodegeneration
...at a compound that protects cells in the body from damage from certain forms of oxygen, a kind of antioxidan...y increase oxidative stressan environment in which damage from levels of reactive oxygen is more likelyin dopamine-producing regions of the brain, areas that ...Scientists discover role of enzyme in DNA repair
... hypothesized that repair enzymes recruited by the damage could shut down the transcription machinery polyme..., Nbs1 or MDC1 transcription continued even after damage was induced. What these results told us was that these proteins were responsible for shutting down...Support for chromosomal theory of cancer found in cancers' development of drug resistance
...ons, leading to resistance, or could inactivate or damage the doors through which a drug enters a cell. Duesberg counters that aneuploidy is simpler and can explain the common development of resistance to many unrelated drugs within the same cancer. He has shown in experiments that aneuploidy causes many ...Double honors for diabetes researchers
...rizes for their research into the peripheral nerve damage suffered by people with diabetes. Dr Caroline Ab...s less likely than white Europeans to suffer nerve damage caused by diabetes. Meanwhile, Dr Sally Price, in the Faculty of Life Sciences, made it a Manchest...Cord blood may preserve insulin levels in children with type 1 diabetes
...he idea would be to intervene and repair any early damage during the honeymoon period many patients enjoy -- the first several months after diagnosis during which insulin needs are minimal, he added. Our groups concept is that we wont be able to cure diabetes without a combination therapy approach, Haller...Weizmann scientists discover a new line of communication between nervous system cells
... stop or cure it. Today, we cant reverse the nerve damage caused by these disorders. But if we can understand the mechanisms that control the process of wrapping the axons by their protective sheath, we might be able to recreate that process in patients. ...Nanotechnology, medicine and bioethics
...ditions such as Alzheimers, nerve injury and brain damage from stroke. Dr. Andrew Maynard, chief science advisor for the Wilson Centers Project on Emerging Nanotechnologies, and Dr. Mauro Ferrari, chairman, Department of Biomedical Engineering, University of Texas Health Science Center at Houston, have be...Can you hear me now? Stem cells enhance hearing recovery
... may be complete or partial. Such loss may involve damage to inner ear cells called cochlear fibrocytes, which are fundamental to inner ear function. Some natural regeneration of these cells can occur after acute damage, leading to partial recovery of temporary hearing loss. But could such restoration be en...Omega-3 fatty acids protect eyes against retinopathy, study finds
...may show merit in future research on diseases that damage retinal blood vessels and nerve cells. "The purpose of our study was to discover and describe the scientific basis for any possible protective role of omega-3 fatty acids against retinopathy, said Lois E. H. Smith, M.D., Ph.D., senior investigator ...Alzheimer's drug based on Purdue -- designed inhibitor begins clinical trials
...roduce toxic proteins that harm the brain, causing damage that eventually leads to dementia. Later that year, Ghosh built a molecule that binds to this key enzyme and inhibits its activity, a beta-secretase inhibitor. "These molecules fit together like puzzle pieces," Ghosh said. "We created a molecule ...Rutgers, Penn researchers capture research dollars to improve prostate cancer diagnostic methods
...cus radiation on that region and reduce collateral damage to neighboring tissues and organs. The researchers are also applying CAD techniques to histology, or the detailed analysis of tissue samples taken during biopsies. Just as radiologists differ in their interpretation of prostate images, pathologists...NJIT professor says certain home shapes and roofs hold up best in hurricane
...tructure on an open foundation reduces the risk of damage from flooding and storm-driven water. ...Bee researcher at Arizona State University is 1 of 20 new Pew Scholars in the biomedical sciences
...the first work on plasticity of neuronal oxidative damage and honeybee behavioral physiology, where cumulative data show that age-related cell damage can be reversed. Amdam has authored or coauthored publications in Nature, Public Library of Science ...Fever after smallpox vaccination tied to individual genetic variations
...d by the IL-1 and IL-18 genes are linked to tissue damage in viral myocarditis, raising the question of whether a more severe complication of smallpox vaccination might be associated with variations in these genes. Although none of the study participants developed this rare complication, it has been documen...UCF nanoparticle offers promise for treating glaucoma
...e the eye, which, if left untreated, can result in damage to the optic nerve and vision loss. High pressure occurs, in part, because of a buildup of carbon dioxide inside the eye, and the compound blocks the enzyme that produces carbon dioxide. Seal and a team of collaborators including Sanku Mallik, of ...Inflammation is at the origin and progression of diseases such as diabetes or cancer
...emains active and becomes chronic, it can severely damage the affected tissue. Asthma, rheumatoid arthritis, inflammatory bowel disease, psoriasis, multiple sclerosis, Alzheimers disease and, most recently, type 2 diabetes and cancer, are diseases that have been associated with chronic inflammation. Ca...Remicade data in ankylosing spondylitis show improvement in spinal mobility and spinal inflammation
... by activity scores on MRI to long-term structural damage in AS is unknown....UD awarded $11M for osteoarthritis research and unique mentoring program for women scientists
...sed to improve knee function without further joint damage and aid in developing screening tools to identify patients who will benefit from rehabilitation programs....Improving plants' abilities to cope with saline conditions
...n significantly reducing the self-induced membrane damage that takes place under the plants stressful conditions. The altered plants were also shown to have greater salt tolerance. The work by Levine and Leshem published in a recent article in the Proceedings of the National Academy of Sciences (PNAS) i......uses hijack their host cells' tools for fixing DNA damage and use those tools to enhance their own reproduction. The DNA damage response normally fixes DNA errors caused by radiation or other environmental factors, or mistakes a...