JCI table of contents, December 1 2004
...in the cell, and therefore prevent cell death. The data suggest that PGE2 or other drugs that increase AKP...us cells to act against tumor-derived cells. This data indicates that NK cells are key players in tumor surveillance in such malignancies. The authors sugg...Common lineage suggested for viruses that infect hosts from all three domains of life
... diseases, including respiratory infections. Using data from their own and other laboratories, the researchers have created structure-based models to demonstrate structural similarities in the coats--proteins and architecture--among viruses that infect hosts from all three domains of life. The three domai...Read your shampoo's label: Study finds common ingredient stunts developing neurons of rats
...art because of the considerable lack of scientific data about a compound that he came to realize was liste...d any published neurotoxicity reports, or concrete data in any public documents filed with the Environmental Protection Agency. The first set of studies he...Yerkes researchers discover baisis for determining handedness in chimpanzees
...an language brain region. A detailed review of the data showed the asymmetries in the KNOB corresponded to right- and left-handedness whereas the asymmetries in the language area did not, leading the researchers to conclude handedness is linked explicitly to the KNOB and not other brain regions. In a sep...New drug sidesteps Gleevec resistance in human trials
...ol-Myers Squibb in Princeton, NJ, report the first data from human clinical trials of the new compound, BM... to Gleevec. "The bottom line is that our in vitro data indicate that this drug is active against all of the mutations except for one," Sawyers said. At the...Science to restore the nation's ecosystems
... climate changes are not understood. Paleoclimatic data show regional temperature changes of up to 10 C, extreme changes in mean annual or seasonal precipitation, and large changes in ecosystems. Given the likelihood of abrupt climate changes in the future, we consider their potential impacts on ecosystem...Tracking orangutans from the sky
...s. Conservation efforts depend on having reliable data on population size, density, and distribution, but estimates of orangutan numbers in Sabah--which range from 2,000 to 20,000--are outdated. Orangutans are tough to spot directly, so researchers traditionally count the nests they sleep in at night, wh......rns is not clear. But these results offer valuable data for conservation strategies and captive breeding programs....Study urges caution in contaminant source tracking
...ed by multiple lines of evidence, such as land use data and presence of wastewater chemicals such as caffeine, when pointing to sources of contamination. Both the client and the analyzing laboratory have a part in making sure interpretations are accurate." Prior source tracking research reports cit...Stanford study links obesity to hormonal changes from lack of sleep
...d six-day sleep diaries. The researchers' data showed a 14.9 percent increase in ghrelin and a 15.5 percent decrease in leptin in people who consistently slept for five hours compared with those who slept for eight. Mignot said the results were consistent regardless of participants' gender, BMI o...Study reveals developing countries with recipe for thriving health biotech industries
...books, background and policy documents, and patent data were also analyzed. The findings were subsequently validated through verification of the case studies with interview participants and presentation at the Canadian Program on Genomics and Global Health's (CPGGH) Genomic Policy Executive Cour...NIDCR launches unique initiative on oral biofilm
...esearch in Rockville, Md. "But just having the raw data will allow everyone to explore more broadly than e...nformation, metagenomics has introduced a scale of data collection rarely, if ever, seen in biology. As published this year, Venter et al. collected sample...Researchers discover direct link between agricultural runoff and massive algal blooms in the sea
...ts. "The availability of high-resolution satellite data has opened up a whole new opportunity to look at the importance of what's going on on land in the sea," Matson added. "This study shows that you have to pay attention to the land-sea connections." ...New approach studying protein structure could advance drug development
...orious and expensive X-ray crystallography. "The data collection only takes a couple of minutes," said M...if not months to complete--causing a bottleneck in data collection and analysis. Furthermore, high quality crystal structures are tough to attain, and only ...Draft sequence of chicken genome completed
...to the human genome. Researchers can use these new data as a tool to identify similar sequences in humans ...obe assembled and analysed this genome. All of the data has been deposited into freely available public databases (see notes). "Having the chicken genome se...What have scientists learned since Mount St. Helens erupted?
...esearch Station, spent the next 25 years analyzing data that enabled him to produce long-term data sets to use to study the ecological patterns and processes of species survival and colonization. He ...Carbon sink or carbon source? Aerosols play role in shifts
...he summertime; these locations were chosen because data on aerosols and carbon fluxes, or the changes in the carbon absorption and emission rates, were readily available. Sites ranged from grassland in Alaska to mixed forestland in Wisconsin to cropland in Oklahoma. Before showing the effects of aerosols...NC State gets $1.59M grant to map genome of parasitic worm
...naging the ubiquitous worm. The resulting sequence data will be made public, so other researchers interested in certain aspects of the root-knot nematode how it develops, establishes a host-parasite interaction or evades host defenses, for example will then be able to use the map of the parasite's genes...NIH provides $32.8 million to enhance biomedical informatics research network
... M.D. "BIRN's powerful and flexible approaches to data integration are designed to accommodate the dynami...facilitating sharing, analysis, visualization, and data comparisons across laboratories. A central premise of the BIRN cyberinfrastructure is that the phys...Chicken genome analysis unlocks secrets of mammalian and bird evolution
...f California, Davis, uncovered a treasure trove of data when they analyzed the recently sequenced chicken genome, a development that will benefit research in basic biology and medicine for years to come. Their analysis of the chicken genome -- the first genome of a livestock or bird species to be sequence...