Tag: "daughter" at biology news
Bursts of waves drive immune system 'soldiers' toward invaders
... actin physically blocks Hem-1 from recruiting its daughter
Hem-1 on one side, so Hem-1 is sequentially added only in one direction. This determines the direction of cell movement. Weiner likens it to a Lego tower on its side. "If you kept adding blocks to one end and removing them from the other, you woul...
ESF EURYI award winner aims to stop cancer cells reading their own DNA
...ode and making sure it is encoded correctly in the daughter
cell. In healthy cells it is important that this process works normally, but in cancer cells it is a natural target for disruptive therapy. Specifically targeting these molecular motors in cancer cells would then prevent the cancer cells from growing...
A unique arrangement for egg cell division
...e does not divide equally to produce two identical daughter
cells. Instead, it undergoes a reducing division, which halves its genetic material to generate a single egg cell with 23 instead of the normal 46 chromosomes in humans. It is crucial that the egg has half the normal set of chromosomes, because the s...
Researchers find pathway that controls cell size and division
...anisms precisely regulate cell size to ensure that daughter
cells have sufficient cellular material to thrive ...still small, resulting in the formation of smaller daughter
cells. The third enzyme in the pathway, UgtP, physically interacts with FtsZ to prevent ring formati...
Chromosome glue repairs damaged DNA
...atids come apart too early, there is a risk of the daughter
cells getting the wrong number of chromosomes, so...y half the copied genetic material ends up in each daughter
cell. Another large research question is how cells repair damaged DNA and consequently prevent cance...
Marine worm opens new window on early cell development
...ccumulation of beta-catenin in only one of the two daughter
cells after each cell division. They showed that t...umulation forms a molecular switch between two new daughter
cells, causing the cells to be different from one another. This universal mechanism operates in embr...
St. Jude study yields secrets of chromosome movement
...ical set of chromosomes gets passed on to each new daughter
cell. Errors in this critical part of cell division can cause one daughter
cell to get extra copies of some chromosomes that should have moved into the other daughter
Muscle weakness: New mutation identified
...the muscle weakness experienced by a woman and her daughter
with a β-tropomyosin mutation, i.e., muscle weakness in the absence of macro or microscopic signs of muscle wasting. The results from single fibre contractile measurements and in vitro motility analyses demonstrated a mechanism where tropomyosi...
Researchers shed light on shrinking of chromosomes
...have to be copied and distributed equally into two daughter
cells at every division. Condensation, the shorten...ibuted during cell division we know very well; two daughter
cells with either broken chromosomes or different numbers of chromosomes result and severe diseases ...
News tips from the Journal of Neuroscience
... divide a set number of times, about eight, before daughter
cells finally heed external cues and differentiate into oligodendrocytes. This week, Dugas et al. tracked down the molecule that makes up this mitogen-dependent intracellular timer. The cyclin-dependent kinase inhibitor p57 Kip2 was transiently upre...
A matter of force
...cell divides, normally the result is two identical daughter
cells. In some cases however, cell division leads to two cells with different properties. This is called asymmetric cell division and plays an important role in embryonic development and the self-renewal of stem cells. Researchers from the European M...
Asymmetry due to perfect balance
... This site is used as a marker for the growth of a daughter
cell during cell division. To establish a cap Cdc42 molecules have to accumulate in a small region of the cell membrane and it is important that this area is defined with high precision. The new data show that this is achieved mainly through endocyto...
News tips from the Journal of Biological Chemistry
...f its constituents are distributed between the two daughter
cells while others divide into two parts, which ar... apart and then segregate randomly between the two daughter
cells. The scientists also determined that a protein called Dynamin-related protein 1 (Drp1) -- know...
UNC scientists discover cellular 'SOS' signal in response to UV skin damage
...hey must replicate, or copy, their DNA to form new daughter
cells. If damage in the DNA is discovered even after the cell has given a "go-ahead" to replicate its DNA, the Timeless/Tipin complex sends a signal throughout the nucleus of the cell to slow the rate of replication. This slowdown may give the cell ...
Biotechnology Study Center honors Joan V. Ruderman, Salvador Moncada and Charles N. Serhan
...uces cells to complete mitosis and divide into two daughter
cells. More recently, her work has revealed how another kinase, Aurora-A, collaborates with cyclins and CDKs to control the timing of entry into mitosis, as well as the process of chromosome segregation during mitotic exit and cell division. Numero...
Accolades for York's commitment to women in science
...are of their son, aged six, and their 18-month-old daughter
is made easier.But she says: "Something which seems to happen to female scientists with young children is that your research time is compromised by teaching duties. You might like to work 60 hours a week, but you can't when you have a small child. ...
New cell type identified in cancer development
...e with healthy or recovering immune systems. These daughter
cells, however, were likely to die, especially when they encountered signals to further differentiate a strong contrast to the behavior of normal stem cells. "We thought this was an interesting development," says Gao, "because these precancerous c...
Researchers at IRB Barcelona discover a new mechanism that regulates stem cell division
...tem cell must divide to guarantee the asymmetry of daughter
cells. The intracellular asymmetry of two functionally distinct centrosomes is a decisive factor in the regulation of asymmetric stem cell division and prevents the proliferation of these cells. These studies have been possible thanks to sophistica...
Making daughters different -- how immune cells take divergent paths when fighting infections
... infection. But how, after replicating, do the new daughter
cells know to become fighter cells that are expend...xamples have been well-characterized that show how daughter
cells can be different in their inheritance of molecules that regulate cell fate. The Science paper ...
Stem cells determine their daughters' fate
...ypes in the fruit fly's gut. The fate of any given daughter
appears to depend on a protein, called Delta, whic...otch signaling genes were disabled or blocked, the daughter
cells continued to divide, eventually producing tumors. "Each individual stem cell seems to have a...
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