Report: How 10 top new technologies will help world reach globally-agreed goals by 2015
...gains in the battle against a suite of the world's deadliest diseases." Global Genomics Initiative "Every year 11 million children die before reaching their 5th birthday," says co-author Elizabeth Dowdeswell, former UN Under Secretary-General and Executive Director of the UN Environment Programme. "Recent r...JCI table of contents November 1, 2004
...bits Cancer Metastasis Identified Melanoma is the deadliest form of skin cancer, primarily because of its highly metastatic nature. One class of proteins called semaphorins could play a role in the development of tumor metastasis as they have been shown to block the migration of some cell types in culture. Mi...Scientists reveal molecular secrets of the malaria parasite
... the complete genome of Plasmodium falciparum, the deadliest human malarial parasite. Hall says the Science paper is important because: The study takes an "evolutionary approach" to exploring how the Plasmodium genome has evolved. By comparing four sequenced genomes (the human malaria P. falciparum and ...Chemical compounds present in diet increase risk of colon cancer
...t frequent type of cancer in humans and the second deadliest in industrialised countries. Its causes, however, are not fully understood, but diet is believed to play an important role. It is thought that vegetables, fruit and fibre-rich foods protect against it; fats, red meat, as well as excessive consumption...New approach to cancer treatment shown to be highly effective
...Therapeutics, Inc. could someday treat many of the deadliest solid and liquid tumors. This unique monoclonal antibody, called SphingomabTM, was tested in several animal models of human cancer and was shown to significantly retard cancer growth on a consistent basis; in some cases, it eliminated the tumor alto...NIH awards Georgia Tech/Emory $11.5 M for nano cardiology research
...cular mechanisms responsible for one of the U.S.'s deadliest diseases. The National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), has awarded researchers from Georgia Institute of Technology and Emory University $11.5 million to establish a new research program focused on creat...Engineered skin offers clues to melanoma development
...ed in the development of melanoma. Melanoma is the deadliest form of skin cancer, resulting from the malignant transformation of cells called melanocytes. Over the past four decades, the incidence of melanoma has risen 15-fold, a more rapid increase than that of any other cancer. "The only current treatment is...Tiny zebrafish teaches researchers how to fight off a deadly cancer
...ts into the development of malignant melanoma, the deadliest form of skin cancer. In a study described in an article in the August issue of Developmental Dynamics, the laboratory groups of Mary J. C. Hendrix, at Feinberg, and of Robert A. Cornell, at The University of Iowa Carver College of Medicine, showed t...High-powered gene profiles provide clues to genes involved in common form of lung cancer
...he most common type of lung cancer and one of the deadliest of all malignancies and a range of possible targets for future therapies. The study will be reported in the Proceedings of the National Academy of Sciences' Online Early Edition ( www.pnas.org/papbyrecent.shtml ) the week of June 27. "Previous stu...US/African project deciphers deadly parasite genome
...irst author of the 2002 paper on the genome of the deadliest human malaria parasite, says that several of the malaria parasite's metabolic pathways that Theileria lacks are found in an intracellular structure called the apicoplast. "This information could be used to develop drugs that could be targeted specifi...Forsyth scientists find three bacteria associated with oral cancer
...of oral squamous cell carcinoma (OSCC)--one of the deadliest of cancers because it often goes undetected in its... stages live for five yearsXplacing OSCC among the deadliest of cancers. "Far too many people are not diagnosed until their oral cancer is in its advanced stages...Immune system's distress signal tells bacteria when to strike back
...study this in Pseudomonas because it is one of the deadliest infections for patients who undergo major surgery," said Alverdy. "We suspect something very similar, however, occurs in all sorts of infections." Inflammatory bowel disease patients, for example, have elevated cytokines the chemical messengers tha...Newfound roadblock to interferon effectiveness against malignant melanoma
...o established therapies. Malignant melanoma is the deadliest form of skin cancer, and if not treated successfully, it can spread to affect the liver, lungs, or brain. Chemotherapy fights the disease with limited efficiency, and the use of interferon has become the most established immunotherapy for advanced-st...Tulane receives multi-million grant for hemorrhagic fever research
...dy designed to develop better tests for one of the deadliest group of diseases called viral hemorrhagic fevers. In partnership with the U.S. Army Medical Research Institute of Infectious Diseases in Ft. Detrick, Md., and three corporate partners, Robert Garry and his Tulane team will develop modern diagnostic...Avian flu in perspective: New England Journal article reviews 'spectacular' findings
... is what happened during the 1918 Spanish flu, the deadliest of last century's three pandemics. A "reassortment" virus that mixes bird flu with already circulating human influenza strains to create a new strain. This was the case during the 1968 Hong Kong flu pandemic and the 1957 Asia flu pandemic. (Most o...'Fish with chips' reporting from ocean top highlights at Census of Marine Life mid-point
...tion to the epicenter of the December2004 tsunami, deadliest in recorded history, Censusbiologists found little or no effect on deep-sea faunaexcept at one site off Sumatra roughly 4000 m (2.5miles) deep, where five months after the disasterthere was no evidence of large animals during an 11hour dive. The abse...Scientists lift malaria's cloak of invisibility
The world's deadliest malaria parasite, Plasmodium falciparum, sneaks past the human immune system with the help of a wardrobe of invisibility cloaks. If a person's immune cells learn to recognize one of the parasite's many camouflage proteins, the surviving invaders can ...Plant-derived vaccines safeguard against deadly plague
...ts into vaccine production factories to combat the deadliest form of plague. The vaccine elicits a protective immune response in guinea pigs. The results are considered to be a milestone in the future development of a new vaccine for human use. Plague, caused by a rod-shaped bacterium called Yersinia pestis, n...New cellular flaw found in some virulent breast cancers
...een in about 10 percent of breast cancers and the deadliest ones. The cancer results from a cascade of molecular events. The overproduction of a common protein, cyclin D1, hyperstimulates a growth switch, CDK4 kinase, causing it to unleash a virulent proliferation of cancer cells and creating a tumor with a v......r, which is developing a compound from the world's deadliest snake the taipan into a treatment for heart disease."...