Time running out for South Asian vultures, ecologists warn
...ndard veterinary dose of diclofenac shortly before death were lethal to captive vultures and that a high proportion of wild vultures found dead in Pakistan were contaminated with diclofenac and had the same symptoms as the poisoned birds in their experiments. The most recent population surveys in India, ca...DNA sequence controls expression of gene involved in cancer
...mally, bcl-2 produces a protein that inhibits cell death or apoptosis. This protein keeps death-promoting factors from producing holes in the mitochondria which can result in calcium and destructive proteins leaking out into the cell. However, the overexpression of bcl-2 in damaged cells can lead to the co...An embryonic stem cell model for Parkinson's disease
...stress has long been associated with neuronal cell death and neurodegenerative diseases like Parkinson's. Proving a causal relationship between oxidative stress and neurodegeneration, however, requires establishing a molecular mechanism. These results support a link between oxidative damage and disease, an...Research team develops nonhuman primate model of smallpox infection
...ined route of infection. According to the authors, death usually occurred within six days of inoculation. Similar results were seen in monkeys that received the same dose of either virus by the intravenous route alone. Having demonstrated that it was possible to achieve lethal infection of primates using ...Use of aspirin or other NSAIDs increases survival
... COX-2 enzymes, NSAIDs may enhance programmed cell death (apoptosis) and inhibit the development of blood vessels (angiogenesis) that feed a tumor. The Fox Chase researchers concluded that inhibiting these COX enzymes holds promise in prostate cancer treatment and warrants further studies. In addition to ...September/October 2004 Annals of Family Medicine tip sheet
...l-related mortality still the most common cause of death in young adults, the authors recommend primary car...l admission and other life events, like a birth or death in the family. The study further found that although patients want contact, most would never initiat...NIH awards Emory and Georgia Tech $10 million for partnerships in cancer nanotechnology
...the most common cancer and second leading cause of death in American men. Approximately 180,000 new cases are diagnosed yearly, and 40,000 men will die from the disease this year. As they age, most men will develop either benign (non-cancerous) prostate enlargement or prostate cancer. Currently, the mos...UCR researchers identify key plant enzyme that defends against multiple infections
...that is required for this process. Programmed cell death (PCD), which occurs naturally in all multi-cellula...ole in initiating and carrying out programmed cell death in animals. Caspase-like activities have also been shown to be required for the initiation of progr...T cell's memory may offer long-term immunity to leishmaniasis
... leishmaniasis, a disease that causes considerable death and disfigurement across the globe and has been fo...shmaniasis, which infects internal organs, causing death if left untreated. Particularly vexing to researchers has been the fact tha...FSU scientist links iron imbalance to Parkinson's disease
...or the illness, while accelerating the decline and death of those already diagnosed with the disease. ...tates Parkinson's symptoms and hastens decline and death in existing victims. Until further studies determine optimal levels of the essential nutrie...New study on smallpox in monkeys reveals tactics of a killer
...e findings shed light on how the virus caused mass death and suffering, and will help point the way to new diagnostics, vaccines and drugs that would be needed in the event of a smallpox bioterror incident. The study, led by David Relman, M.D., of Stanford University, is now online in the Proceedings of th...Gladstone researchers resolve key Huntington's disease mystery in Nature cover story
...e whether a particular abnormality predicted early death and might be pathogenic, or predicted longer survival and might be beneficial. The findings suggest, says Finkbeiner, that inclusion bodies lock up mutant huntingtin in other parts of a cell and keep it from interfering with the rest of the neuron in...Study using robotic microscope shows how mutant Huntington's protein affects neurons
...red their overall risk of death. The rate of cell death was higher in neurons with larger gene mutations, but the death rate for each set of cells remained constant over time. The researchers also examined the level o...Flies have morning and evening clocks
...sed genetic techniques to selectively deliver cell death genes to ablate specific groups of neurons. They then observed how these genetic deletions affected the flies' activity. The experiments revealed that the PDF-expressing ventral lateral neurons govern the morning activity peak; while another group of...The CF Foundation urges all states to include newborn screening for cystic fibrosis in test panels
...line in respiratory function, the primary cause of death in CF. Advances in CF treatment and care, have had a significant impact on the length and quality of life for people with CF. Research on newborn screening for CF has shown further clinical benefit when therapeutic interventions were administered ne...The long road to a promising malaria vaccine started at NYU School of Medicine
... against severe malaria, which is a major cause of death in children in Africa. It is not yet an ideal vaccine because it is expensive, requires three doses, and it isn't known yet how durable the vaccine's protection will be, but it is a very big step forward." The vaccine, designated RTS.S/AS02A...Urine testing might prove to be an alternative screening test for cervical cancer
...ncer is the second leading cause of cancer-related death among women. The routine way to screen for cervical cancer is through Pap screening and pelvic exams. "More studies involving a much larger group of women need to be done, but we are hopeful about the potential of urine testing as a cost-effective ...Experimental lupus drug may also work against atherosclerosis
...rtery disease by blocking key arteries, leading to death and disability.Mishra, assistant professor of internal medicine rheumatology, and his colleagues tested TSA on experimental mice that were bred to lack a significant natural protection against atherosclerosis. For 12 weeks, these mice were fed a die...Gene linked to greater risk of heart disease in type 2 diabetes
... for coronary artery disease, the leading cause of death for this group. "We now have potential gene markers to help identify diabetes patients at increased risk for heart disease," said Alessandro Doria, M.D., Ph.D., Investigator in Joslin's Genetics and Epidemiology research section, Director of Joslin's...Genetically modified parasite lets researchers probe immune system's memory
...y 12 million people worldwide, causing significant death and disfigurement. It may also help efforts to develop vaccines for other pathogens including AIDS and tuberculosis. Scientists have known that successful recovery from Leishmania infection immunizes humans and animals against subsequent infection. B...