Other highlights in the December 20 JNCI
... ... In the last several years, researchers have discovered a small population of so-called cancer-initiating cells (also called cancer stem cells) in several cancers. These cells can self-renew and maintain the growth of a tumor, whereas its daughter cells cannot. Scientists are studying the properties of cancer-initiating c...JCI table of contents: December 14, 2006
... Alzheimers disease (AD) is one of a number of neurodegenerative disorders in which brain cells damaged by naturally occurring chemicals known as reactive oxygen species (ROS) have been observed. However, whether this oxidative damage causes neurodegeneration or is a consequence of it has not been previously determined. A study appearing online on December 14, in advance of publication in th...American Chemical Society's Weekly PressPac -- December 6, 2006
... ...Weekly PressPac -- ALL CONTENT IS FOR IMMEDIATE USE EXCEPT ...ARTICLE #5 (EMBARGOED FOR 9 A.M., EASTERN TIME, DEC. 11, 2006) ... ... The American Chemical Society (ACS) News Service PressPac is your access point for discoveries in fiel...JCI table of contents: December 7, 2006
... Although the soluble factor TGF-beta has been shown to suppress the growth of tumor cells in the early stages of breast cancer, high levels of TGF-beta during the later stages of the disease are associated with a poor outcome. A study using human breast cancer samples and mice, which appears online on December 7 in advance of publication in the January print issue of the Journal of Clinical...Scientific meeting on pulmonary hypertension, December 7-8
... ... Why: Pulmonary hypertension, or continuous high blood pressure in the blood vessels of the lungs, is a disabling and often fatal disease, which affects people of all ages from newb...Highlights from the December 2006 Journal of the American Dietetic Association
... ...Young adults who often purchase their own food and prepare meals at home eat fast food less often, eat more fruits and vegetables and have better overall diet quality than those who are not involved...... ... Early this year, the US Supreme Court remanded to a lower court cases relating to whether intermittent streams are under the jurisdiction of the Clean Water Act. Intermittent streams are currently threatened by the possible outcomes of the court cases. In this study, P.J. Wigington Jr. (US Environmental Protection Agency) and colleagues found that intermittent streams are an important...JCI table of contents: December 1, 2006
... ... In a study appearing in...JCI table of contents: December 22, 2005
... ...Enzyme triggers plaque rupture in hardened arteries, causing heart attack and stroke... ...University of Washington researchers have revealed that, in mice with atherosclerosis, it is the expression of an active form of the enzyme MMP-9, by macrophages located within plaque buildup in narrowed coronary arteries, that triggers plaque rupture. This rupture can cause blood clots and block bl...Also in the December 21 Journal of the National Cancer Institute
... address methodologic issues that surface when studying biomarkers....... The concentration of biomarker antibodies, antibodies against proteins that scientists use to measure the progression of a disease, can affect what a certain level of protein expression indicates about patient survival....JCI table of contents: December 15, 2005
... ... Reminiscent of the 1966 sci-fi thriller Fantastic Voyage, where a surgical team is miniaturized and injected into a dying man, researchers from Harvard Medical School have used injectable self-assembling peptide nanofibers loaded with the pro-survival factor PDGF-BB to protect rat cardiomyocytes from injury and subsequent heart failure. Their study appears online on December 15 in advanc...Other highlights in the December 7 JNCI
... A new study in mice has found that chronic stress may increase susceptibility to a type of skin cancer that is induced by ultraviolet (UV) radiation by suppressing T cells and certain molecules that support immune function.... ...Both chronic stress and exposure to UV radiation suppress the immune system, but the mechanism by which suppression occurs is not fully understood. A group of scie...Highlights from the December Journal of the American Dietetic Association
The December 2005 issue of the Journal of the American Dietetic Association contains articles and research studies you may find of interest. Below is a summary of two of this month's articles. For more information or to receive a copy of a Journal article, e-mail . ... ... ...Researchers at Texas Tech University say french fries prepared in non-hydrogenated cottonseed oil are significantly lowe...JCI table of contents: December 2005
... ...... Although the use of vaccines has decreased the incidence of childhood whooping cough, the causative agent, Bordetella pertussis, somehow remains endemic in vaccinated populations where the bacteria causes a coughing illness of variable severity. This poses a threat to children who are too young to be vaccinated, and who often get whooping cough from adult, nonsymptomatic, or mildly s...JCI table of contents December, 2005
... ...... In a paper appearing online on November 10 in advance of print publication of the December issue of the Journal of Clinical Investigation, Brian O'Rourke and colleagues from Johns Hopkins University describe how failure of the mitochondrial network at the muscle-cell level leads to differential electrical excitability in hearts subjected to ischemia and reperfusion. ...... This work i......... , Iichiro Shimomura and researchers from Osaka University, Japan, show that fat cells of obese mice produce increased levels of toxic oxygen molecules known as reactive oxygen sp......... Alzheimer disease (AD) is the most common form of dementia in the elderly and classic clinical features include memory loss, deterioration in speech, and behavioral disturbances. Doctors increasingly concede that central to the cause of AD is the production and accumulation of beta-amyloid (Abeta), which is toxic in the brain. There are only a few clinical therapeutic options for AD patie...