Researchers find protein that makes long-term memory possible
...pstead, M.D., Ph.D, of Cornell, and her colleagues deciphered the chemical reaction leading to the formation of mBDNF. In that study, Dr. Hempstead and her coworkers reported that the enzyme plasmin chemically converts the early, or precursor, form of BDNF--proBDNF--into mBDNF. Previously, other researchers...Dream home: Malaria parasite renovates to suit its tastes
...es and proteins involved in malarial infection and deciphered the signalling code, which is critical for the protein export mechanism. "We have tried removing certain proteins from the parasite gene knockouts, for example and the parasite survived well in most cases. So those proteins were not useful drug ta...Scientists decipher genome of bacterium that helps clean up major groundwater pollutants
Rockville, MD Scientists have deciphered the genome sequence of a microbe that can be used ...eading center for microbial genomics, TIGR has now deciphered the genome sequences of numerous microbes that have potential for use in bioremediation. Those inclu...Scientists decipher genome of fungus that can cause life-threatening infections
...tant field of biomedical research, scientists have deciphered the genomes of two closely related strains of Cry...estigator Claire M. Fraser, the President of TIGR, deciphered the genome of one strain of C. neoformans while researchers led by Richard Hyman at Stanford Univers...Researchers map genome of deadly fungus
... a long-term collaborative effort, scientists have deciphered the genomes of two strains of a fungus that can le...estigator Claire M. Fraser, the President of TIGR, deciphered the genome of one strain of C. neoformans while researchers led by Richard Hyman at Stanford Univers...Progress toward a more targeted treatment of Alzheimer's disease
... years ago, Bart De Strooper and other researchers deciphered the process by which the plaques originate. A major role in this process is played by γ-secretase, an enzyme that cuts proteins in a particular place. Sometimes the γ-secretase cleavage goes wrong, causing the creation of a by-product that ...Penn researchers determine structure of binding site of colon-cancer drug and its protein target
...s receptors. The resulting structural information deciphered by Ferguson and colleagues emphasizes the importance of drug research targeting active protein receptors on cancer cells and tumors. As is the case in Erbitux, "the protein EGFR needs to not only be present on tumors but it needs to be there and be a...Genome study of beneficial microbe may help boost plant health
...ed to greatly benefit crop plants, scientists have deciphered the genome of a root- and seed-dwelling bacterium that protects plants from diseases. The research provides clues to better explain how the helpful microbe, Pseudomonas fluorescens Pf-5, naturally safeguards roots and seeds from infection by har...'Achilles' heel' of the herpes virus possibly found
...ene that controls the production of that receptor, deciphered some aspects of the receptor's structure, and developed a pig-cell system that could be used to test new anti-herpes drugs. The findings may help explain why the oral and genital herpes virus has such a successful track record: The receptor, dubbed ...Scientists crack 40-year-old DNA puzzle and point to 'hot soup' at the origin of life
...uzzle that has baffled scientists since they first deciphered the language of DNA almost 40 years ago. In 1968, Marshall Nirenberg, Har Gobind Khorana and Robert Holley received a Nobel Prize for working out how proteins are produced from the genetic code. They discovered that three letter 'words' - known as co......e complete genetic code of the rice plant has been deciphered by researchers at The University of Arizona's plant sciences department and UA's BIO5 Institute and other members of an international consortium. The genome sequence is published in the current issue of Nature. The UA research team was led by Rod Win...New vaccine protects more effectively against tuberculosis
...for the high efficacy of this vaccine has now been deciphered (Journal of Clinical Investigations, August 18, 2005). Globally, tuberculosis remains the number one killer in adults. Moreover, multi-drug-resistant tuberculosis strains are on the rise which cannot be treated by first-line drugs. A vaccine against...Scientists crack code for motor neuron wiring
...d Hughes Medical Institute (HHMI) researchers have deciphered a key part of the regulatory code that governs how motor neurons in the spinal cord connect to specific target muscles in the limbs. The researchers said that understanding this code may help guide progress in restoring motor neuron function in peopl...Flatworm genes may provide insights into human diseases, researchers say
...uld vital information about many human diseases be deciphered from genes inside freshwater flatworms? A definitive yes is not the answer yet, but research at the University of Illinois at Urbana-Champaign has provided an important advance for pursuing both that idea and the biology of stem cells. In a paper app...Chemical signaling helps regulate sensory map formation in the brain
..., "information from the eyes could not be properly deciphered by the brain." "Topographic maps are a very common wiring strategy in our brains," he said. Similar systems are thought to regulate other sensory systems -- such as hearing and touch, as well as motor systems -- but the visual system has been the pr...No-mow grass may be coming to your yard soon
...ghes Medical Institute scientists report they have deciphered the signaling pathway for a key class of steroid hormones that regulates growth and development in plants. "By manipulating the steroid pathwaywe think we can regulate plant stature and yield," said Joanne Chory, a Howard Hughes Medical Institute i...TWAS, Illycaff announce Trieste Science Prize winners
...iseases. Rao led a team of Chinese researchers who deciphered the first crystal structure of the coronavirus, which causes Severe Acute Respiratory Syndrome (SARS). His findings provide a potential framework for the design of anti-SARS drugs. The SARS epidemic infected more than 8,000 people and caused more tha...Structure of enzyme offers treatment clues for diabetes, Alzheimer's
...ty of Chicago and Argonne National Laboratory have deciphered the three-dimensional structure of insulin-degrading enzyme, a promising target for new drugs because it breaks down not only insulin but also the amyloid-beta protein, which has been linked to the cognitive decline of Alzheimer's disease. In the...New behavior may use old genes
...es. The genetic basis of social behavior is being deciphered through the efforts of ASU researchers and their work with the honeybee, Apis mellifera. The recently completed honeybee genome sequence is aiding that effort by providing DNA sequences of genes that may be involved in social behavior, according to ...... Chemical Society James Watson and Francis Crick deciphered the structure of regular DNA 53 years ago. Now, scientists from Stanford University have determined the structure of xDNA. That's "expanded DNA," a strange double helix molecule that is 20 percent wider and more heat-resistant than natural DNA. Inh...