Bugs in the gut could play key role in understanding human disease and drug toxicity
...that we now need more research into this area. The deciphering of the human genome was a huge step forward for medicine, but we now need much more research into the microbes found in the gut and how they interact with their mammalian hosts' metabolism. Understanding these interactions as will extend human biolog...Researchers find protein that makes long-term memory possible
...s/conversion_model_image.cfm .) However, deciphering a chemical reaction in test tubes does not prove that the same reaction occurs naturally in the brain or that the reaction underlies the formation of long-term memory. "In the Science article, we describe a series of experiments showing t...Structure of new DNA enzyme family member found
...ng the structure of AIRs kinase is another step in deciphering what proteins look like, a major goal of the National Institutes of Health, which funds the Ealick research group's work. "Often, two proteins with the same function have no sequence similarity," says Ealick, whose research group works with crystalli...Virginia Tech, TIGR sign memorandum for new alliance
...rst plant genome, Arabidopsis thaliana, as well as deciphering the genome sequence of rice. TIGR's bioinformatics department is creating and maintaining gene databases and has produced new software for finding genes in bacteria, plants, parasites, and other organisms, as well as software for identifying other i...Scientists advocate genomic sequencing of 'living fossil'
...paign in the December issue of Genome Research for deciphering the genetic code of a "living fossil" fish, the coelacanth. The genomic sequence of this large "hollow-spined" fish, which populates deep-sea volcanic caves, could hold valuable clues for biologists studying the evolution of vertebrate species. Coe...... for Neural Engineering whose life's work has been deciphering the way in which nerve cells code messages to each other. Now, a camera-and-microphone surveillance system is using his insights to recognize -- instantly, and with high accuracy - the sound of a gunshot, and only a gunshot within a two-block radi...New findings in innate immunity may lead to treatments for atherosclerosis
Bethesda, MD Scientists are one step closer to deciphering the molecular signaling process controlling innate immunity with the discovery that a molecule called IRAK1 regulates the expression of the anti-inflammatory cytokine IL-10. Because atherosclerosis patients often have elevated IL-10 levels, IRAK1 may...Scientists uncover clues to the mystery of 'gene deserts'
...on tool called Mulan - shown to be instrumental in deciphering evolutionary clues by comparing multiple primate, mammalian and fish species with chicken - were Stubbs and Gabriela Loots of LLNL, Marcelo Nobrega of the Genomics Division at LBNL, and Ross Hardison, Webb Miller, Belinda Giardine, Minmei Hou and Jia...Microbe's genome reveals insights into ocean ecology
...ful in wider studies of marine ecology. By deciphering and analyzing the DNA sequence of Silicibacter pomeroyi , a member of an important group of marine bacteria, scientists found that the metabolic strategies of marine bacterioplankton are more diverse and less conventional than previously thought. ...'From the Sidelines' describes the making of a scientific revolution
...s earlier research made major contributions toward deciphering the genetic code, understanding the nature of frameshift mutations, and the structure of the T4 phage genome. Lotte Streisinger is a Eugene-based artist known for her work in clay and her dedication to the arts community. She co-hosts "Visible City,"...Scientists develop split green for tagging protein
...field of protein biotechnology and work related to deciphering the structure and function of proteins. I like to think of it as an enabling technology, a toolbox, if you will, for protein researchers, that could help them close the gap between sequencing the DNA of the human genome and determining the structure...Scientists decipher genome of bacterium that helps clean up major groundwater pollutants
... boost such efforts. There are several reasons why deciphering a microbe's DNA sequence can help scientists find better ways to use it. For one, the analysis of that sequence helps researchers learn about how the organism functions on a metabolic level. In the case of D. ethenogenes, scientists found 19 differen...Story tips from the Department of Energy's Oak Ridge National Laboratory, February 2005
...ouse strains that could serve as animal models for deciphering the complex molecular interactions underlying skull development. Mutations in the gene that codes for a novel cell-signaling protein affected skull and spine growth in mice. The strains could serve as models for craniosynostosis, a condition where a ...'Color-blind' method opens new doors in DNA sequencing
.... Even with complex computer programs to assist in deciphering the signals, this "cross-talk" between the dyes results in subtle variations that can cause nucleotides to be miscalled. The new method developed at BCM and Rice, called pulsed multiline excitation, uses four lasers, each matched to a particular dye.......a population geneticist. One of his specialties is deciphering prehistoric human relationships using genetics. By comparing the genetic markers, the UA scientists' work will unveil new aspects of people's family trees, ones that are almost impossible to discover through traditional genealogical methods. In contr...Scientists take aim at virulent bacteria by decoding machinery of key control enzyme
ATLANTA--By deciphering the ingenious mechanism used by a particular enzyme to modify bacterial chromosome chemistry, scientists have come a step closer to designing a new kind of drug that could stop virulent bacterial infections in their tracks. Their research will be pu...Researchers map 'circuitry' of yeast genes using technique that could be applied to humans
...their positions in the new wiring diagram. "Beyond deciphering the circuitry of a yeast cell, our analytical approach can be applied in humans to find what years of research using other methods have failed thus far to uncover: combinations of genes that are the true culprits in many diseases," said Ideker, a pro...Social amoeba sheds light on communication in human brain
...he functioning of the GABA receptor. "The trick in deciphering complex signals between cells is to find an experimental system that is complex enough to have the signals that are interesting, but simple enough to permit you to test your hypothesis," said Loomis. "Once you have an idea of how things work, it is ...Georgia Tech develops mass spectrometry device that analyzes proteins faster and at a lower cost
...as only the beginning of a much more complex task deciphering the secrets of cellular chemistry and the mechanisms of disease. While the genome serves as a blueprint to understanding the body, proteins represent the materials that carry out these plans. There are about 2 million distinct proteins in the human b......many possibilities for virus binding to cells make deciphering the entry process a difficult problem to solve. The gene that encodes B5 had in fact been sequenced, but not characterized, as part of the Human Genome Project. Discovering its role and studying the HSV entry mechanism was tricky and near impossibl...