Promising new preventative treatment option for population of men at high risk of prostate cancer
...options available, doctors and patients often feel defenseless against the onset of prostate cancer. "Fortunately, these results offer a promising new preventive approach to prostate cancer treatment. A chemopreventive agent like toremifene is a first step toward the possibility of stopping prostate cancer befor...Defenseless plants arm themselves with metals
...in the absence of metal, however, these plants are defenseless against diseases like powdery mildew, a common fungal infection that most other plants fight off with ease. In most plants, exposure to powdery mildew and other pathogens triggers the plant defense pathway, a series of biochemical events that occur i...Gladstone investigators discover how resting T cells avoid HIV infection
...iral particles. In resting T cells, though, HIV is defenseless against A3G, because there is no Vif in the incoming viral particles and the virus has not advanced far enough into its life cycle to make new Vif.......mutated slightly, suddenly becoming harmful to the defenseless mice. "One or two changes in amino acids made the difference between a virus that kills and one that does not kill mice," said Agbandje-McKenna, who is associated with both UF's McKnight Brain Institute and the UF Genetic Institute. "We wanted to ...