Brain circuit may permit scientists to eavesdrop on memory formation
...an observe that as the delay increases, the memory deficit decreases. These data suggest that the importance of the neocortex as a memory storage site increases with the lifetime of the memory. In addition, there is a clear need for the hippocampus and cortex to talk to one another." One candidate for the co...Reductions in blood oxygen levels in newborns could contribute to ADHD development
...one factor leading to the development of attention deficit hyperactivity disorder (ADHD). This research will be reported at the Society for Neuroscience annual meeting in San Diego on October 24 by Glenda Keating, PhD, and Michael Decker, PhD, of the Department of Neurology at Emory University's School of M...Children's Hospital Boston launches major genetic study of autism
...lity to recognize and respond to faces (a critical deficit in autism), the development of specific language skills (also impaired in autism), and gross and fine motor function. Although not a formal part of the study, the data collected by MIT will be fed back into the Children's study and correlated with t...Genetic defect confers risk of major depression, resistance to SSRI drug therapy
...iety, post-traumatic stress disorder and attention deficit hyperactivity disorder. SSRIs counteract the depletion by slowing the re-uptake of serotonin, allowing the body to make the best use of abnormally low levels of the chemical messenger, the researchers explained. Scientists had long considered the en...Study examines relationship of vitamin A pathway to breast tumor progression
...somatic CRBP-I loss of function results in a local deficit in vitamin A storage and metabolism that has profound consequences for the affected tissue, despite presumably normal circulating levels of vitamin A," the authors write. "The consequence of deficient vitamin A storage is a fundamental point that nee...Clam embryo study shows pollutant mixture adversely affects nerve cell development
...mysteries as autism spectrum disorder or attention deficit hyperactivity disorder. To test her hypothesis, MBL scientist Carol Reinisch and her colleagues treated developing surf clam embryos ( Spisula solidissima ) with different combinations of BCE and studied their effects on nerve cell growth. "On ...Neuronal 'traffic jam' marks early Alzheimer's disease
... some mechanistic connection between the transport deficit and plaque deposition. "So, our hypothesis is that in familial Alzheimer's disease -- or in disorders such as Down syndrome where beta-APP is overexpressed -- those defects cause early failure in cellular transport," he said. "And those failures then...Fruit fly study points to treatment for fragile X syndrome
...lso causes accompanying sleep disorders, attention deficit disorder, hyperactivity, aggression, and autistic behavior. Researchers Sean M.J. McBride from Albert Einstein College of Medicine, Thomas A. Jongens from University of Pennsylvania School of Medicine, and their colleagues studied a mutant strain of ...Separate genes influence speed, accuracy in decoding written words in dyslexia
...arge body of evidence pointing to it as a hallmark deficit in dyslexia. The UW group also has published a finding that this deficit is detectable in children and adults. Dyslexia is a complex learning disorder that affects 5 to 10 ...Alcohol 'binges' in rats during early brain development cause circadian rhythm problems
...me (FAS) have altered sleep wake cycles, attention deficit and hyperactivity disorders, and display other disruptions in behavior. And third, the changes in circadian rhythms caused by developmental alcohol exposure may affect chronotherapeutic treatment of diseases because the efficacy and side effects of...Brain-injury rehabilitation depends on acetylcholine circuitry
...e control group of rats recovered about 55% of the deficit in their reaching ability, while the rats lacking a cholinergic system recovered only about 18%. In other experiments, the researchers compared the plasticity of brain reorganization in a brain region known to be "cholinergic independent" with the ar...Natural glucose byproduct may prevent brain damage and cognitive impairment after diabetic coma
...ith glucose did not show any significant cognitive deficit compared to the control group. Followup necropsy of brain tissue evaluated four areas of the hippocampus most vulnerable to damage from hypoglycemia: CA1, dentate granule cell, subiculum, and perirhinal cortex. The rats receiving glucose plus pyruvat...Ocean climate predicts elk population in Canadian Rockies
...per cent of their diet. "The elk are already at a deficit in the winter. There is less grass to eat, and their bodies have to work harder and use more energy to stay warm," said Hebblewhite, who studies in the U of A Department of Biological Sciences. Cold, wet weather alone is enough to decrease an elk pop......e must have increased to compensate. The resulting deficit of important amino acids as well as more starch and fat could lead to poorer health in offspring who develop under those conditions....Natural relaxant protects against asthma, may yield new therapy
.... Our findings suggest the disease may stem from a deficit in the natural bronchodilator that normally relaxe... said. "Our results further suggest that the GSNO deficit seen in patients with asthma may result from increased GSNO reductase activity," he continued. "The ...New finding in studying dopamine transporter
... variation linked to substance abuse and attention deficit hyperactivity disorder (ADHD). "Healthy people who carry a particular variant of the dopamine transporter gene, the nine repeat allele, have significantly higher levels of dopamine transporter in the brain," said the lead author, Christopher van Dyck...Pediatricians lack confidence in managing obesity, and their own weight might be an important factor
... felt much more confident about treating attention deficit hyperactivity disorder than treating obesity." The investigation involved surveying by mail 738 N.C. pediatricians who belonged both to the American Academy of Pediatrics and the N.C. Pediatrics Society. The adjusted response rate was 71 percent. "In...NIH awards $11.9 M to The Burnham Institute to establish the San Diego Chemical Screening Center
... drugs for behavioral diseases including attention deficit disorder, substance abuse, schizophrenia, and bipolar disease, and drugs for pain management....The self's broken border: Tracing the role of agency attribution in schizophrenia
...ions of influence in schizophrenia may be due to a deficit in a general mechanism that allows healthy individuals to properly attribute agency to sensory experiences....UT Southwestern researchers discover master switch in cell death
...id. For instance, a tumor may contain cells with a deficit of Mule, making the tumor more likely to grow and perhaps be resistant to chemotherapy. Treatment might then focus on the biochemistry of Mule and Mcl-1, he said. "We might be able to see if there's a problem with Mule, or perhaps we could screen bef...