Gene with broad role also causes prevalent, inherited nerve disorder
...ype 1, the speed of the nerve impulse slows due to degradation of the protective myelin sheath that normally covers nerve axons, Zchner explained. Axons are the cable-like extension of the neuron from the cell body in the spinal cord to the juncture, or synapse, between the nerve ending and muscle. Demyelinated ...Multi-purpose protein regulates new protein synthesis and immune cell development
... And third, it activates genes involved in protein degradation to get rid of excess unfolded proteins. So you reduce the load, get rid of garbage and increase efficiency. If these don't work, the cell will die." "Recently, scientists have discovered that the unfolded protein response is activated in many disease...Assessment of recent rapid land-cover change yields portraits of global human impact
...ncrease is prominent in Southeast Asia. But forest degradation is also increasing rapidly in Siberia, mostly as a result of logging, and the southeastern United States and eastern China are experiencing rapid cropland decrease. Lepers and her colleagues note that information is not complete globally, and the sy...Gene used in brain development can cause childhood brain cancers
...nded RNA (dsRNA) into a cell, where it induces the degradation of complementary messenger RNA, thereby suppressing the gene expression. "In our studies, we applied several specifically designed RNAi to the tumor cells that expressed OTX2," Yan said. "We then observed that the RNAi knocked down OTX2 expression a...Scientists discuss improved biopesticides for locust control in West Africa
...biopesticides is low in the environment because of degradation from sunlight," Agblevor said. "We have developed coating technologies to improve on the environmental persistence of the biopesticide, specifically a lignin coating for the spores, which increases their resistance to ultraviolet radiation." Research...Heroes of the sea, Pew Fellows' fifteenth class tackle sharks, reefs, mangroves and more
...ip, McCook will expand his expertise in coral reef degradation and explore how managers can support reef resilience in the face of damaging climate change. Dr. Jurgenne Primavera is a mangrove specialist and a Researcher in the Southeast Asian Fisheries Development Center in the Philippines. Primavera's work wil...JCI Table of Contents, March 1, 2005
...damage, normalized kidney enzyme levels, inhibited degradation of the proximal tubule, increased protective enzymes, and suppressed cell death. The work will be of interest in the field of kidney diseases and therapeutics. TITLE: Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney fro...Singers (and parents) take note: Worst songbird rehearsals precede best debuts
...al abilities, many of the birds displayed dramatic degradation in the quality of their songs relative to how well they performed at the end of the previous day. However, the quality of these birds' songs improved after intense morning rehearsal to the point where by the end of each new day, their singing was ind...K-State professor to discuss feeding the world's population without poison
... becomes a vicious downward spiral causing further degradation and undermining human health." According to Rice, technology for better management of the soils and waters is available now for sustaining soil and water while providing food, fiber and energy for the world's population. Rice recommends several rem...Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
...ial human pathogens. The analysis reveals the degradation of the E. histolytica genome in its transition from a free-living organism into a parasite of the human gut. At the same time, scientists also cataloged the retention and expansion of some gene families characteristic of more complex organisms. ...Cooperation is keya new way of looking at MicroRNA and how it controls gene expression
... these AU-rich elements built in. AU-rich element degradation involves a number of different proteins, including...inding events may play a role in the stability and degradation of the mRNA. Despite much research over the last few years into exactly how this works, the question...Histamine, anxiety and alcoholism
... because this is the enzyme which accounts for the degradation of histamine in mammalian brain," said Gabor Oroszi, a researcher at the National Institute on Alcohol Abuse and Alcoholism and first author of the study. "Since clinical experience with antihistamine drugs has indicated that blockade of histamine 1...Insight into natural cholesterol control suggests novel cholesterol-lowering therapy
... rate of cholesterol production by stimulating the degradation of cholesterol-building reductase. The availability of reductase, which functions early in the synthetic process, largely determines the rate of cellular cholesterol production, Debose-Boyd said. When added to intact cells and cellular components in ...Advances in the characterisation of the oyster mushroom genes
...nes involved. But nobody, to date, has tackled the degradation of cellulose from a molecular perspective. Cellulo...ld seem logical that the genes responsible for the degradation of one or the other are located close together on the genome, on the same chromosomes....Marine researchers deliver blueprint for rescuing America's troubled coral reefs
...n islands--Oahu, Maui, Kauai and Hawaii--also show degradation similar to that of the Florida Keys, according to the authors. And while reefs in the isolated northwest Hawaiian Islands remain in relatively good condition, they, too, are showing signs of decline: "Monk seals and green turtles are endangered; lar...Scientists collaborate to assess health of global environment
... rate than any time in history." The environmental degradation carried out to meet demand for food, fiber, timber, fresh water, fuel and other resources has begun to jeopardize more subtle services that nature has always provided free of charge, he said. Making matters worse, he added, the world's poorest people...Essential mangrove forest threatened by cryptic ecological degradation
...that the worrying aspect of the research is that a degradation of the most vulnerable, most socio-economically im...The authors emphasize that such cryptic ecological degradation must be acknowledged by policy and decision makers if mangrove protection is an aim. The research te...Global team member comments on landmark ecosystem report
...nnium Ecosystem Assessment, said the environmental degradation outlined in the project's first report is alarming...e of fisheries, the emergence of new diseases, the degradation of water supplies and other abrupt changes that will seriously affect human health, the report state...Earth's services in peril, report concludes
... very short time with little warning. Poverty and degradation of nature may turn into a downward spiral, in which poor communities have fewer options to conserve natural resources, the abuse of land increases and even greater poverty results. The impact of ecosystem disruption often falls first and most heavil......iquitin, to mark hTERT for destruction by cellular degradation machinery. Increasing the amount of MKRN1 in cells promotes the degradation of hTERT and leads to a decreased telomerase activity. This degradation is even more pronounced in c...