Model simulates dynamics of heart rhythm disorders
...aviour of individual human heart muscle cells. She demonstrated that the behaviour of this model corresponded well... chaotic pattern of many small waves. Ten Tusscher demonstrated that in a healthy heart, stable three-dimensional spiral waves arise after the administration of sev...Shots fired at Bayonne range prove smart gun technology works
...here was no applause as shots rang out, the action demonstrated that smart gun knew friend from foe. Sixteen electronic computerized sensors embedded in the gun's grip distinguished known from unknown users. "We've only just begun and we're pleased to say that we're getting 90 percent reliability when scanning ...DFG loosens eligibility requirements for the Emmy Noether Programme
...ence abroad and scientific independence, generally demonstrated by two years of postdoctoral experience, are required. In addition to this, personal selection interviews are being introduced and the age limit is being replaced by a regulation that allows approval for the programme with up to four years of postdo...Body's biological clock found to affect cardiac rhythm patterns in healthy adults
...ts and or one of 1000 beats. "These studies have demonstrated that this self-similar structure in the temporal order of heartbeat fluctuations changes with certain behaviors, such as sleep or wake, rest or exercise," explains Ivanov. "Based on these observations, we hypothesized that these dynamic patterns wil...Tips from the Journals of the American Society for Microbiology
...s indicating highly virulent strains. "Our study demonstrated that houseflies carry virulent E. coli O157:H7 in the farm environment primarily during the summer and may play an important role in the ecology and transmission of this pathogen among individual cattle and potentially to the surrounding farm and urb...Immune system contributes to evolution of a new fluorescent protein
...ien. And in earlier studies, other researchers had demonstrated that SHM could be induced in B cells to repair a single mutation in a non-antibody gene. "This finding hinted that the process might be useful for generating multiple mutations," he said. "But it's like taking a perfectly typed manuscript, introducin...Fundamental finding yields insight into stem cells, cancer; opens door to drug discovery
...ke Professor Robert Lefkowitz, M.D., also at Duke, demonstrated that beta-arrestin2 does indeed interact with activated Smoothened in cells. That interaction promotes the internalization of activated Smoothened, a finding entirely consistent with the protein's newly recognized role in the signaling pathway, Lefko...Evidence that human brain evolution was a special event
...ok at specific genes, Lahn and his colleagues have demonstrated "that the candidate gene approach is alive and well," said Varki. "They have found lots of interesting things." One of the study's major surprises is the relatively large number of genes that have contributed to human brain evolution. "For a long ti...Vollum Institute discovery may unlock human genome
...uzzle a little simpler." The discovery already has demonstrated its implications for human diseases. Goodman's lab is working with the OHSU Cancer Institute on a cancer-causing oncogene that arises when a rearrangement of chromosomes generates an abnormal transcription factor. "If you had a technique that would a...Scientists identify molecular events that drive cell senescence
...ted with chromatin structure. The researchers also demonstrated that HIRA and ASF1a, two known regulators of chromatin structure, play a key role in formation of SAHF. When human cells were genetically manipulated to activate HIRA and ASF1a, the cells assembled SAHF and showed markers for senescence. If ASF1a was...Holes in fossil shells show effects of competition and evolution
...ccess. The shift in feeding behavior patterns was demonstrated in the lab, and shown in the fossil record bridging the extinction and recovery of marine species in the western Atlantic at the end of the Pliocene Era. In the lab, under competitive conditions, 37.5% of the shells showed edge drilling, while only 2...JCI table of contents, 3 January 2005
... of this therapy. These researchers previously demonstrated that mouse embryonic stem cells can differentiate into neurons when cultured under specific conditions. These same culture conditions, technically simple and efficient, were recently applied to primate embryonic stem cells and resulted in the generat...Transplantation of monkey embryonic stem cells reverses Parkinson disease in primates
...tion of this therapy. These researchers previously demonstrated that mouse embryonic stem cells can differentiate into neurons when cultured under specific conditions. These same culture conditions, technically simple and efficient, were recently applied to primate embryonic stem cells and resulted in the generat...The giant eagle of Middle Earth
...questioned their authenticity." The research team demonstrated that the New Zealand giant was in fact related to one of the world's smallest eagles--the "Little Eagle" from Australia and New Guinea, which typically weighs under 1 kg. "Even more striking was how closely genetically related the two eagle species ...Protein in urine may warn of preeclampsia risk in pregnant women
...n who went on to develop preeclampsia. The results demonstrated that urinary PIGF levels were dramatically lower in the preeclamptic patients at both the time of clinical symptoms and in the six to eight weeks prior to the onset of symptoms. To ascertain that decreased urinary PIGF is specific to preeclampsia, th......be enhanced with this new treatment. This has been demonstrated through trials over many years, starting with mice and, currently, in vitro trials are being undertaken with human cells. Positive results have been achieved in all these trials, the conclusion being that a substance should not be rejected out of h...Study examines relationship of vitamin A pathway to breast tumor progression
...ding protein I (CRBP-I). A study of CRBP-I in mice demonstrated that the protein plays an essential role in vitamin A storage. In addition, CRBP-I expression is down-regulated in about a quarter of human breast cancers. However, it is not known if reduced CRBP-I function compromises vitamin A bioactivity and, if ...Zebrafish may hold key to understanding human nerve cell development
...ashington. "Using zebrafish as a model, we've demonstrated that glial cells play a previously unidentified role in regulating the development of sensory hair cell precursors -- the specialized neurons found in the inner ear of humans that make hearing possible. This research increases our understanding of ho...Scientists discover unique microbe in California's largest lake
...rt of the cell's protein synthesis machinery, they demonstrated that chlorophyll d -producing blue-green algae (more technically known as cyanobacteria) have acquired a piece of DNA from a proteobacterium, a distant relative that last shared a common ancestor with cyanobacteria more than two billion years ago. T......taxel nanoparticles, is free of toxic solvents and demonstrated a superior response rate with an almost doubling o...ial Hospital. "The pivotal clinical trial results demonstrated that ABRAXANE had superior response rate when compared to Taxol in patients with metastatic breast c...