US researchers uncover the science behind the breast cancer protective effect of olive oil
...ry) in Annals of Oncology[1]. The researchers have demonstrated in a series of laboratory experiments on breast cancer cell lines that oleic acid dramatically cuts the levels of an oncogene called Her-2/neu (also known as erb B-2). High levels of Her-2/neu occur in over a fifth of breast cancer patients and are a...New comparative toxicogenomics database
...nt for predicting toxicity. Classical studies have demonstrated that even closely related species can have dramatically different responses to chemical exposures. Data provided by CTD will provide insights into the genetic basis of these differences. The CTD prototype is a community-supported public resource fun...New lensless imaging technique opens door to nanoscale world
...tanford Linear Accelerator Center (SLAC). "We have demonstrated the first direct imaging technique that will work with LCLS, opening the door for taking pictures of ultra-fast changes in the collective behavior of ensembles of atoms and molecules," said SSRL physicist Jan Luening. He and BESSY colleague Stefan Ei...Anti-seizure drugs slow aging in worms
...ant food and looked well-fed. The researchers also demonstrated that anticonvulsants did not extend life by protecting the worms from pathogenic bacteria in their environment. Ethosuximide and trimethadione did, however, significantly delay age-related declines in neuro-muscular activity. Treated worms continued ...Research identifies promising route for treating age-related hearing loss
...the cells to begin proliferating. "This experiment demonstrated that it was a direct effect of the Rb gene and not some indirect effect during development that controlled proliferation of hair cells," said Corey. "So Zheng-Yi has found that deletion of this gene can allow functioning hair cells to continue to d...Clam embryo study shows pollutant mixture adversely affects nerve cell development
...ts individually, this is the first time anyone has demonstrated that BCE's components can work together to adversely affect neuron growth in a model organism. The study, which is reported in the January 2005 issue of Environmental Toxicology and Pharmacology, is the first step toward understanding how expos...Thinking small: Texas A&M team creates lab-on-a-chip
... one billion times smaller in volume than has been demonstrated by conventional methods. Their work was recently published in Applied Physics Letter and featured in several science journals. Their research is funded by The Robert A. Welch Foundation and National Science Foundation grants. "It might be possible to...Tips from the journals of the American Society for Microbiology
...nd from household dust from the infant's home were demonstrated to be genetically similar," say the researchers. "This genetic similarity suggests that airborne spores of C. botulinum in an infant's surroundings may cause infant botulism and, as in this case, also result in the fulminant form of the illness that...UCLA/VA researchers discover fat gene
...e obese mice with excess lipin in their fat tissue demonstrated even lower blood-sugar levels than normal mice with regular levels of lipin. "Because obesity and lipodystrophy are both associated with insulin resistance and high blood sugar, we hope that our results may point to new therapies for diabetes," said ...Mouse brain cells rapidly recover after Alzheimer's plaques are cleared
... that become swellings. Scientists have previously demonstrated that such swellings make it difficult or impossible for nerve-cell branches to send signals. After showing that the swellings were mostly stable in number and size over the course of three to seven days, Brendza injected Abeta antibodies directly ont...Timing is everything: First step in protein building revealed
...tes the ribosome's activity. The research team has demonstrated that eIF1's mere presence on the yeast ribosome prevents the machinery from getting started. Only after its release from the complex can the ribosome start making proteins. "No one had any idea when eIF1 was released from the ribosome, or that its r...Lack of enzyme turns fat cells into fat burners
...." In prior studies, Wakil and his colleagues have demonstrated the effect ACC2 has on mice. Mice bred to lack the enzyme can eat a high fat, high carbohydrate diet without gaining weight, while their normal counterparts become obese and develop type 2 diabetes. "This adds another tissue or organ that helps out i...Interaction between stem cells and their niches key to differentiation
...st in mammals and humans. "In our experiments we demonstrated that piwi and bam proteins are expressed independently of each other in reciprocal patterns in germline stem cells and cystoblasts," Lin said. "However, overexpression of either one of these genes antagonizes the action of the other in these cells, a...Novel technology detects human DNA mutations
... and rapid characteristics of this technology were demonstrated with unamplified DNA samples representing all possible forms of three genes implicated in hypercoagulation disorders. ...Columbia research lifts major hurdle to gene therapy for cancer
...nal Academy of Sciences ( PNAS ), the researchers demonstrated that the technique works by incorporating it into a specially designed virus. The virus eradicated prostate cancer cells in the lab and in animals while leaving normal cells unscathed. Gene therapy based on the new technique should also be effective ...Choosing where to look and changing your mind
...ments, researchers at Imperial College London have demonstrated that the medial frontal cortex, an area of the brain previously implicated in controlling actions and making choices, responds differently to choosing freely between actions and changing from one choice to select another one. The new work utilizes fu...Richard Zare awarded the 2005 Wolf Prize in chemistry
...cal limit, namely the single molecule. He has also demonstrated that, at sufficiently high levels of power, he could carry out optical trapping of single molecules--once again demonstrating the ultimate limit of this technique in chemistry." The Wolf Foundation was established in 1976 by the German-born inventor ...Novel approach yields predictions validated by experiments
...ng full circle has new meaning for researchers who demonstrated a promising new approach integrating scientific ex... 2005 issue of the journal Nature. The researchers demonstrated their scientific approach within the context of sphingolipid metabolism in yeast. Sphingolipids are ...Green tea extract boosts exercise endurance 8-24%, utilizing fat as energy source
... properties over the years. The Kao lab "recently demonstrated that the long-term consumption of tea catechins wa...energy metabolism, especially lipid metabolism. We demonstrated that GTE intake improved endurance capacity and this was accompanied by an increase in lipid catabol......e mammals, "but this is the first time it has been demonstrated that TBT could be working directly on the auditory system," said Santos-Sacchi. Mammals are the only group of animals that have outer hair cells. Sensitive hearing in mammals relies on cochlear amplification resulting from the motor activity of outer...