Purdue proves concept of using nano-materials for drug discovery
... - Researchers at Purdue University have built and demonstrated a prototype for a new class of miniature devices t... a reaction and turning blue in the process, which demonstrated that the device works. The Center for Membrane Protein Biotechnology combines a diverse range of res...Robots walk with close-to-human efficiency
... say in their paper. "The success of human mimicry demonstrated here strongly suggests an intimate relationship between body architecture and control in human walking."...Familiar blood pressure drug may prevent osteoporosis
...senty's work started five years ago when his group demonstrated that one of the main functions of leptin, a hormone initially thought only to regulate appetite, is to regulate bone formation. Later, they showed that the sympathetic nervous system mediates only this action of leptin. In the most recent study, the...Individual taste receptor variations determine 'classic' PTC bitterness perception
...n addition, tests on three sample populations also demonstrated that perception of higher concentrations of these bitter compounds is largely determined by which alleles an individual possesses. Thus, the ubiquitous taste differences that make us perceptually distinct are explained to a large degree by which form...Topical treatment shown to inhibit HIV and herpes simplex virus infection
Mount Sinai School of Medicine researchers demonstrated that a gel applied in the vagina provides protection from both the human immunodeficiency virus (HIV) and the herpes simplex Virus. The study, presented at the 12th Conference on Retroviruses and Opportunistic Infections, is the first to show that a ...Internet viruses help ecologists control invasive species
...fessor Norman Yan of Ontario's York University has demonstrated that predation by the spiny water flea causes an average loss of three zooplankton species. Thus, as the species spreads, it could cause loss of thousands of populations of zooplankton species in Ontario alone....Celebrex provides a two pronged attack against prostate cancer
...ally relevant." Dannenberg and his colleagues then demonstrated that celecoxib worked in animals that served as hosts for human prostate tumors. In this animal model, celecoxib not only was shown to reduce proliferation of cancer cells, but also reduced the growth of blood vessels at the tumor sites. As a result...Molecular thermometers on skin cells detect heat and camphor
...at TRPV3 is indeed a temperature sensor. They have demonstrated that mice lacking the TRPV3 protein have specific ...ls able to sense warm temperatures. Now they have demonstrated that the receptor does indeed detect heat by examining the physiological and behavioral characterist...Stealth worms may improve insect pest control
...than a chemical product, but so far they have been demonstrated not to harm humans, livestock, beneficial insects or the environment. Nematodes usually have to be underground; their targets are soil insects." The formulations keep improving as newer isolates of nematodes are found, and there is a lot of commercia...UCSD medical/bioengineering reseachers show titanium debris satobtage artificial joints
...ne and the Jacobs School of Engineering. The team demonstrated that titanium implants are safe in large blocks, b...es causing the greatest weakening. The researchers demonstrated how different-sized titanium particles affected bone-building cells called osteoblasts and bone-dest...Conserved amino acids play both structural and mechanistic roles in sandwich-like protein
...rect the process of protein folding. "We directly demonstrated that in one protein within the large sandwich-like protein family, evolution has indeed preserved amino acids for mechanical reasons," Wittung-Stafshede said. "We believe that our discovery is novel and that it gives important new insight into the in...Pioneering PET/CT research widens applications of imaging for diabetic foot
... glucose (radiotracer 18F-FDG), Israeli physicians demonstrated the presence of infection with PET imaging. CT scans showed the localization of the infection site detected by PET as well as structural changes in bone and soft tissues. "This combined imaging approach in a single session using a single device leads...Basis for DNA ejection from single phage particles
... stretched by applied hydrodynamic flow. The study demonstrated that DNA release is not an all-or-none process, but rather is unexpectedly complex. DNA release occurred at a very high rate, reaching 75,000 base pairs of DNA/sec, but in a stepwise fashion. Pausing times were observed during ejection, and ejection...William C. Rose Award lecture will focus on cytochrome P450
...iochemical and molecular biological research and a demonstrated commitment to the training of younger scientists, as epitomized by the late Dr. Rose. Recent recipients of this award include Sunney I. Chan, Jack E. Dixon, Gordon Hammes, Marc W. Kirschner, and Rowena G. Matthews. The Award consists of a plaque and ...APS announces 2005 Young Investigators Awards
...ssistant professor level, are APS members who have demonstrated outstanding promise in the field of physiology. More than $54,000 in monetary prizes is presented to the recipients and their research programs. Winners will receive their awards on Monday, April 4 at the International Union of the Physiological Sc...Genetic therapy reverses nervous system damage in animal model of inherited human disease
...inary neurology at Penn, the treated cats not only demonstrated dramatic clinical improvement, but MRI also reveal...tions had been made." The large animal study also demonstrated that only a limited number of injections are necessary to introduce the working LAMAN gene, one of t...Biologists discover why 10% of Europeans are safe from HIV infection
... the immune system. Using computer modeling, they demonstrated how this disease provided the selection pressure that forced up the frequency of the mutation from 1 in 20,000 at the time of the Black Death to values today of 1 in 10. Lethal, viral haemorrhagic fevers were recorded in the Nile valley from 1500 BC...New tumor-suppressor gene discovered
..." Lai's lab also performed other experiments that demonstrated that the two protein products of the two genes join structurally at the molecular level to form a larger, more powerful, and more productive protein complex. Because of its far-reaching implications, this study is expected to establish a new area o...Shutting down the HIV assembly line
...embling into particles. Although many studies have demonstrated that Gag is present in the late endosome and have ...e cell. Through a series of experiments, the group demonstrated that the AP-3 delta subunit interacts with Gag to direct it to the multivesicular body. Disruption o...Study: Soap and water work best in ridding hands of disease viruses
...econds, all agents with the exception of handwipes demonstrated a 90 percent reduction of bacteria on the hands." Alcohol-based handrubs were generally ineffective in demonstrating a significant reduction of a relatively resistant virus, Rutala said. While the use of alcohol-based handrubs will continue to be an ...