Faster-acting antidepressants closer to becoming a reality
... Ketamine blocks a...Antidepressants stimulate new nerve cells in adult monkeys, may have implications for humans
... The results, the first from nonhuman primates, are similar to those previously seen in rodents. They suggest that creation of new nerve cells, a process known as neurogenesis, is an important part of antidepressant therapy. Researcher Tarique Perera, MD, at Columbia Universit...Effectiveness of certain antidepressants may be influenced by gene variations of individuals
... Initial drug treatments fail in 30 percent to 40 percent of patients with major depression. Pharmacogenetic (the relation of genetic factors to variations in response to drugs) prediction of response is one possibility for improving antidepressant treatment, according to background information in the article. Polymorphisms (occurrence in more than one form) in the serotonin tra...Common anti-depressants similarly safe and effective for treating postpartum depression
... ... "We've been tr...Research finds genetic link to antidepressants
Researchers in recent years have been trying to identify genetic factors predicting a response to antidepressants. Previous studies have found evidence for the role of corticotrophin-releasing hormone (CRH) in depression. Based on previous findings, researchers have most closely focused on drugs that target serotonin transports, such as Prozac. None of these studies, however, focused on specifi...SSRI antidepressants involve dopamine as well as serotonin signaling
Researchers have discovered that antidepressant drugs such as Prozac not only affect levels of the neurotransmitter serotonin in the brain, but also "hijack" dopamine signaling as well--causing it to launch serotonin signals. Their findings offer new insight into how Prozac and other "selective serotonin uptake inhibitors" (SSRIs) work and how they might cause problems in patients taking them. .....