Gene design program from Johns Hopkins simplifies, automates and speeds design of 'artificial' genes
...ne," said Boeke. Simplifying creation of so-called designer or artificial genes is important because slight changes in the choice of base pairs making up specific parts of the gene can have significant effects on how the gene works and how efficiently it can be inserted into cells. "In the past," said Boeke, ...GlycoFi announces the first production of antibodies with human glycosylation in yeast
...culture, it should be possible to produce specific designer glycoproteins at large scale using the company's engineered yeasts. GlycoFi has already announced several major collaborations aimed at applying its technology to the production of specific therapeutic proteins, including collaborations with Merck, E...New cellular flaw found in some virulent breast cancers
...normal function, or whether it could be blocked by designer drugs to treat breast cancer without harming the patient. Previously, mice engineered to lack cyclin D1 were found to be highly resistant to certain breast cancers, and other experiments showed that mice in which the cyclin D1 gene had been inactivat...Oh, rats! Designer animals reveal possible heart disease genes
.... Now, however, they have a new research ally: the designer rat. In a four-year study published in the Janua...Wisconsin (MCW) systematically bred and studied 43 designer rats with and without high blood pressure, in order to pinpoint candidate genes behind heart disease...JCI table of contents: December 22, 2005
...art enlargement in mice. The availability of these designer mice will also help researchers gain a better understanding of signaling pathways that regulate heart development and function. TITLE : Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mi...Yale environment dean wins book award for nonfiction
...revious year, must be by an author, illustrator or designer who lives or has lived in the state or have a Connecticut setting. Judges choose from nominations made by people in the publishing industry, librarians, teachers and the public....Innovative research set to push boundaries of cancer care
..., vaccines, electric pulses, nano buckeyballs, and designer agents that enter the brain are being featured in a "Novel Approaches" press conference at the Molecular Targets and Cancer Therapeutics International Conference. The November 14-18 meeting is being sponsored by the American Association for Cancer Re...Two designer drugs hit same lung cancer target, but only one is effective
BOSTON--Two designer cancer drugs differed dramatically in a laboratory... growing evidence that mutations in the targets of designer drugs critically influence their effectiveness. Erbitux is an effective inhibitor of EGFR signals in...Tamoxifen-like drug suggests new ways to selectively block estrogen
... various hormones," Greene said. "We could create designer androgens for prostate cancer, or designer glucocorticoids to treat inflammation." Since "the primary regulator of cofactor recruitment is rece...Clearing the air on airplane cabin air
...all cabin air filters. Pall is the world's leading designer and manufacturer of advanced fluid clarification products for the commercial aviation industry as well as for military aircraft, marine and mobile equipment. In addition to aircraft cabin air filters, Pall manufactures a wide range of filters that ar......olitics and film school and then went to work as a designer for Vogue magazine until she tired of fashion. She then became a designer for the British Broadcasting Corp. and wrote award-winning food and travel books before turning to f...Story tips from the Department of Energy's Oak Ridge National Laboratory, February 2005
...tly, this is a significant step toward long-sought designer materials expected to have a wide range of applications, particularly as sensors and switches and in the semiconductor industry. Funding for this research, which is published in the Jan. 27 issue of Nature, is provided by ORNL'S Laboratory Directed R...EB and IUPS - Where cures of tomorrow can be seen in the science of today
... lectures discusses the biomedical implications of designer babies and human clones. Symposia cover topics such as the genetic maps of blood pressure control; computational biology of cardiac arrhythmias; discovery of the genes for polycystic kidney disease; gene regulation for survival at low temperature; ph...Urban ecology study witnessing the birth of a 'designer ecosystem'
...ed. "People in ecology are beginning to talk about designer ecosystems systems that have been heavily influenced by humans. What we're doing is pioneering this," Grimm said....