Tumor individuality useful for guiding rational chemotherapeutic decisions
... mechanisms underlying chemotherapeutic action and detailed knowledge of signaling mechanisms used by cancer cells can be used to guide rational decisions about combination therapy. According to Dr. White, "As it is not likely feasible to clinically test every possible combination of agents, the predictive va...Fossil records show biodiversity comes and goes
BERKELEY, CA -- A detailed and extensive new analysis of the fossil records of marine animals over the past 542 million years has yielded a stunning surprise. Biodiversity appears to rise and fall in mysterious cycles of 62 million years for which science has no satisfactory e...Robot-based system developed at Carnegie Mellon detects life in Chile's Atacama desert
...wed a transect and stopped occasionally to perform detailed surface inspection, effectively creating a "macroscopic quilt" of geologic and biological data in selected 10 by 10 centimeter panels. After the rover departed a region, the ground truth science team collected samples the rover had examined. "Based o...Bayer donates equipment to Children's Hospital, Oakland for infectious disease research
... donated by Bayer BP will enhance the capacity for detailed investigations and research studies at the CIVD. "Because this equipment is so specialized, it is usually only available at much larger research institutions," said Gregory Moe, PhD, research scientist at Children's Research Center, also known as the...Studies expand understanding of X chromosome
...rences between males and females. These studies, a detailed analysis of the X chromosome's DNA sequence and a ...in the current issue of the journal Nature. "These detailed analyses of the X chromosome represent a monumental achievement for biology and medicine. They are e...Researchers at U. Va. discover how body regulates most abundant type of white blood cell
...s blood pressure or water level. Their research is detailed in the March 23 issue of the journal Immunity. Working with laboratory mice, Dr. Klaus Ley, professor of biomedical engineering at U.Va. and a U.Va. graduate student, Matthew Stark, discovered a new type of T lymphocyte, the cells that are the m...American Society for Microbiology to host 105th General Meeting in Atlanta
...w information about bioterrorism preparedness More detailed information, including programs and abstract, will be available in early May. Preliminary programs and press registration materials are currently available and can be obtained by calling the ASM Office of Communications or online at http://www.asm....First real-time view of developing neurons reveals surprises, say Stanford researchers
...what they'll become as adults. The work, which is detailed in a paper in the March 24 issue of Neuron, took place in the brain of a small see-through fish called a zebra fish. Stephen Smith, PhD, professor of molecular and cellular physiology, and graduate student Christopher Niell immobilized a young fish a...AAAS CEO Alan I. Leshner registers 'strong concerns' over suppression of science films
... scientific freedom in America. The article, which detailed the growing trend of science museums declining to show Imax films that mention the process of evolution, explains that fear of protests has prompted some museum managers to scrub such offerings from play lists. The films include "Galapagos," about th...Drezek wins Beckman Young Investigator Award
...mpt to noninvasively collect and analyze extremely detailed information quantifying about a broad spectrum of structural and biochemical features of neoplastic cells. "Today, it would take a battery of tests, including invasive procedures like biopsies, to gather the information that we hope to collect and a...Unlocking genetic mysteries focus of UH symposium
...nderstanding, new collaborations." By performing detailed analyses of genetic material and answering questions related to how the genome is organized, how it changes over time and how genes move from one organism to another, scientists can find solutions to problems such as bacterial resistance to antibioti...JCI table of contents April 1, 2005
...hat regulate feeding behavior. The authors give a detailed and complex analysis of each mouse line, clarifying the role of IRS2 in specific cells of the pancreas and brain. The results suggest that IRS2 may be useful for treating diabetes and obesity. TITLE: The role of insulin receptor substrate 2 in hypot...NYU, Rockefeller researchers find complexity of regulation by microRNA genes
...regulate specific target genes. The paper contains detailed genome-wide predictions for all human microRNAs as well as tissue-specific predictions. Several predictions were validated experimentally. The findings demonstrate an unforeseen staggering complexity of gene regulation executed by microRNAs on a geno...Satellite images give a better picture of sediment transport
...goon. The results show the possibility of making a detailed map of the water turbidity using optical remote sensing, with uncertainty rate less than 20%. The satellite images therefore provide key data for calibration, refining and validation of the numerical sediment-transport models elaborated. This dual ap...Researchers peer inside embryonic/fetal hearts to discover causes of congenital heart disease
... that uses high frequency sound waves to deliver a detailed picture of the heart. Children's also is expanding its interventional cardiac catheterization lab to take advantage of new ways to use catheters as therapeutic devices and is partnering with local biotechnology companies to develop novel approaches t...Study finds no association between diet and pancreatic cancer among men and women
...th Professionals Follow-up Study (HPFS). Analyzing detailed food frequency questionnaires sent to the participants every four years between 1984 (for NHS participants) and 1986 (for HPFS participants) and up to 2000, they identified two dietary patterns; the western diet, consisting of high consumption of red...National Academies news: Spent nuclear fuel storage
...s be performed. These conclusions were based on a detailed review of security analyses performed by the USNRC, U.S. Department of Homeland Security, the nuclear power industry, and independent experts. The committee noted that many security improvements have been instituted at U.S. commercial nuclear power ...Human chromosomes 2, 4 include gene deserts, signs of chimp chromosome merger
The first detailed studies of two of the largest human chromosomes have revealed enormous gene "deserts" lacking any protein-coding sequences and relics of the merger of two ape chromosomes to form a single human chromosome. Scientists from the Genome Sequencing Cente...Scientists analyze chromosomes 2 and 4
BETHESDA, Md., Wed., April 6, 2005 A detailed analysis of chromosomes 2 and 4 has detected the largest "gene deserts" known in the human genome and uncovered more evidence that human chromosome 2 arose from the fusion of two ancestral ape chromosomes, researchers supported by the National Human ......ingly popular now that scientists are accumulating detailed parts lists for many organisms, thanks to genome sequencing projects and other efforts to comprehensively document the components of living entities. "Until now, computer modellers had no defined way of exchanging descriptions of biological systems,...