Antibody retards growth and induces death in liver cancer cells
...hermore, because high expression of PDGFR has been detected in a variety of tumors, such as skin cancer, brain tumors, gastrointestinal tumors, prostate tumors, ovarian cancer and leukemia, Dr. Monga believes these findings could have much broader applications. ...News tips from the Journal of Neuroscience
...ne transfer of myc-tagged BDNF into DRGs was later detected in Schwann cells, consistent with transfer of BDNF from DRG to Schwann cell. Overexpression of BDNF in DRGs also led to anterograde transport, secretion, and enhanced myelination. 2. Making Shaft Synapses Jason Aoto, Pamela Ting, Bita Maghsoo...UF scientists work to develop simple bladder cancer test
...-year survival rate is about 94 percent when it is detected early, bladder cancer is extremely difficult to cure because it tends to recur. Imagine the bladder like a balloon, and the tumors grow into the interior of the balloon, Goodison said. So the surgeons go in and want to be as least disruptive as po...Progenika Biopharma presents a biochip that guarantees safety in blood transfusions
... the totality of blood group incompatibilities are detected in a safer, quicker and more specific analytical process than with the serological technique. Moreover, its cost is twenty times less than DNA sequencing, which enables its generalized and routine use in all blood transfusions. The BLOODchip is the...Researchers identify genetic mutation that may alter tumor cell proliferation
...l samples from cancer patients, yet has never been detected in cancer cell lines. This discovery is a seminal finding in cancer biology that confirms AKT1 as an oncogene in breast, colorectal and ovarian cancer. The mutation alters the electrostatics of binding pocket in the pleckstrin homology domain, the...First baby is born after oocytes were matured in the lab and frozen
...rian syndrome (PCOS) or with ovaries that had been detected to be polycystic by ultrasound (U/S), who took part in the trial at McGill Reproductive Center, Montreal, Canada. The baby is progressing well. Dr Hananel Holzer, who led the team, is an assistant professor at the Center and coordinates the fertili...Personalized approach to ovarian stimulation achieves high ART pregnancy rates
...r of small growing (antral) follicles in the ovary detected during screening. This FSH dose algorithm is simple and easy to use and utilises readily available patient characteristics, said Prof Olivennes, coordinator of the Centre de FIV Eylau La Muette, Paris, France. It is the first to be tested in a pro...Support for chromosomal theory of cancer found in cancers' development of drug resistance
...s than cancer cells, and that as a result a cancer detected early can be knocked back by chemotherapy. His chromosomal theory offers hope of early detection, however, since it ascribes cancer to chromosomal disruption, called aneuploidy, that can be seen easily through a microscope. "By screening for aneupl...News tips from the Journal of Neuroscience
...ine whether iso-orientation maps could be reliably detected with GE fMRI, the authors compared BOLD responses in areas of expected greater neural activation. Indeed, the iso-orientation maps from GE and SE BOLD fMRI matched well with maps based on cerebral blood volume measurements. 4. Aneuploidy in Normal...Scientists identify first gene linked to scoliosis
...urs in otherwise healthy children and is typically detected during the growth spurt that accompanies adolescence. Although scientists have known for years that scoliosis runs in families, its pattern of inheritance has remained unclear. That's because the condition is likely caused by several different gene...Which came first: Primates' ability to see colorful food or see colorful sex?
... red-orange pelage and skin (which are more easily detected with trichromacy) as well as gregarious mating systems that would help in the visual comparison of potential mates. Furthermore, the correlated evolution of red-orange pelage and skin with visual capacity was even more pronounced in species that pos...UGR researchers design an alternative to blood test to detect drugs in the body
...rcotic substances in a persons body can usually be detected by a blood or urine test. By means of a simple technique, doctors can say if someone is under the influence of a drug (through blood), if they have taken it within the last week (through urine) or if they usually take it (through the bile test). Ho...Hepatitis B drug can compromise HIV treatment
...nt protein, so that its replication can be readily detected and quantified. The researchers test viral replication inside the same type of immune system T cell that the virus naturally infects. This system is an extremely sensitive and reliable way to measure inhibition of HIV replication, said Siliciano. A...Scientists ponder plant life on extrasolar Earthlike planets
... Earth-like ones out there, but very few have been detected so far , he said. One of the things that Ive learned is that you have to free your mind from the constraints of thinking that life elsewhere has to be like life here. Energy on any world is critical, he said, and there has to be some system...Reconstructing the biology of extinct species: A new approach
...lve features approximately 1/100 the size of those detected by medical CT scanners. In addition, experienced field workers used personal knowledge or film of animals in the wild to classify species into one of six locomotor categories ranging from very slow and deliberate to fast and agile. The scientists t...Potato wart eyed as risk to potato production
...serious disease of cultivated potato that has been detected worldwide. Potato wart is caused by the fungus Synchytrium endobioticum, which is considered to be the most important worldwide quarantine plant pathogen of potato. While not harmful to humans, the disease causes unsightly growths that initially appe...Remicade data in ankylosing spondylitis show improvement in spinal mobility and spinal inflammation
...ctions in spinal inflammation through two years as detected by magnetic resonance imaging (MRI). The recommend...ing spondylitis. In ASSERT spinal inflammation as detected by MRI was examined. Patients receiving REMICADE showed improvement in MRI Activity scores at week ...454 sequencing identifies HIV drug resistance at early stage
...ic. The additional low abundant resistant variants detected by Ultra Deep sequencing were found to be extremely important as it enabled the prediction of early antiretroviral treatment failure with strong statistical significance. Current genotypic resistance technology available to clinicians is limited to...In nature, proteins sweep up nanoparticles
... the team analyzed the zinc sulfide aggregates and detected the characteristic signal of proteins. Next, to further zero in on this intriguing signal, they examined the sample using an extremely high-spatial-resolution imaging tool called secondary ion probe spectrometry, which is located at the Department ...University of Pittsburgh researchers culture blood-forming stem cells from human fat tissue
...ng method known as flow cytometry, the researchers detected a broad spectrum of blood-forming, or hematopoieti...h early and mature red blood cells. Moreover, they detected CD34+ cells at approximately the same frequency as is present in freshly isolated bone marrow. In bo...