Triplex assay used to assay duplex genomic DNA
Direct detection of base sequence in duplex nucleic acid has long b...y sensitive diagnostic assay allows for the direct detection of base sequence in human genomic duplex samples, thereby obviating the use of PCR which has inheren...Story tips from the Department of Energy's Oak Ridge National Laboratory, March 2007
...ting chemotaxis proteins translate their exquisite detection abilities into a signal. The work of Igor Zhulin of ORNL's Computer Science and Mathematics Division and Roger Alexander of Georgia Tech, published recently in Proceedings of the National Academy of Sciences, represents a giant step in this area and...ESA's Medspiration project branches out to support biodiversity
...ll include Mesoamerican biological corridor change detection maps, coral reef maps, ocean water quality monitoring services, mangrove maps as well as a map of dry lands. Medspiration allows users to open very high-resolution maps, down to two square kilometres, anywhere in the world, as illustrated by the m...New sensor detects gaseous chemical weapon surrogates in 45 seconds
...nd emerging defense and homeland security chemical detection requirements. The technique, called Quartz Laser P...S is an extremely sensitive and selective chemical detection technique that can be miniaturized and yet is still practical to operate in field environments," sai...Alien predators are more dangerous than native predators
... defences such as camouflage colouring that reduce detection or help them escape if they encounter a familiar predator. "The finding brings new insight and urgency to the challenge of how best to target management programs aimed at protecting native species from predation," says Dr Peter Banks, UNSW biologis...New cell type identified in cancer development
...s well as offer new options for cancer prevention, detection and treatment. Current cancer stem cell theory holds that tumors are comprised of a variety of cell types. Among them is a small subset of rather primitive cells that, like other stem cells in the body, are self-sustaining, self-renewing and multi...Super small nanoelectrodes can probe microscale environments
...de with an appropriate chemical, we can target the detection of specific chemical species." The researchers have demonstrated that their nanoelectrode can sense the chemical environment within a droplet 10 microns in diameter. Their next step is to show that the probe can penetrate the cellular membrane of a l...Microscopic sea creatures provide foundation for gas sensors and other devices
... humans. "When we conducted measurements for the detection of nitric oxide, a common pollutant, our single diatom-derived silicon sensor possessed a combination of speed, sensitivity, and low voltage operation that exceeded conventional sensors," said Kenneth H. Sandhage, a professor in the School of Materia...Global Nephrology gathers in Rio
...eping with the ISN's global efforts aimed at early detection and prevention of CKD, other sessions will focus on the global kidney disease epidemic, kidney disease in minority groups and developing countries, infectious and environmental causes of renal disease, tropical nephrology and regression of CKD. Inter...Green tea and COX-2 inhibitors combine to slow growth of prostate cancer
... cells of the prostate and is used as a marker for detection and progression of prostate cancer. These results, combined with a marked decrease in the presence of cancer-promoting proteins, offered clear indications that green tea and celecoxib, combined, could be useful in slowing prostate cancer growth, Mukh...Monochloramine treatment not as effective in protecting drinking water
...d degradation of chemical threats as well as early detection of contamination. As it reacts with a contaminant, chlorine levels in the water drop. Many municipalities use chlorine levels as indicators of possible contamination. Monochloramine also requires more time to kill microbial contaminants in water....Ingredient in Big Macs and sodas can stabilize
COLUMBIA, Mo. The future of cancer detection and treatment may be in gold nanoparticles tiny p...ing and therapeutic applications, including cancer detection and therapy. The promise of nanomedicine comes from the high surface area and size relationships of ...Anti-herpes treatment reduces HIV levels in women infected with both viruses
...expected, there was also dramatic reduction in the detection of symptomatic and asymptomatic presence of HSV-2. The effects appeared to gradually increase over the 3 month follow-up period, with no sign of abating.' These results indicate a new way to possibly reduce the sexual transmission of HIV from already...Biologically inspired sensors can augment sonar, vision system in submarines
...wimming, predator and obstacle avoidance, and prey detection and tracking. Equipped with an artificial lateral line, a submarine or underwater robot could similarly detect and track moving underwater targets, and avoid collisions with moving or stationary objects. The artificial lateral line consists of an int...Other highlights in the Feb. 21 JNCI
...o select patients for further testing may increase detection of Lynch syndrome, a disorder that predisposes people to developing colorectal cancer at a young age. Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer (HNPCC), is caused by mutations in DNA mismatch repair genes, the genes t...Largest-ever search for autism genes reveals new clues
... create a din of statistical noise that drowns out detection of signals from linked sites in the genome," explained Dr. Bernie Devlin, University of Pittsburgh, who served as a corresponding author on the project along with the University of Toronto's Dr. Stephen Scherer. "To amplify these signals, we brought ...Successful development of prototype assays
...Homogenous Assays include: Sensitive and specific detection of a type specific antibody, IgG, induced by specific infection with either HSV 1 or HSV 2, with little or no cross reactivity between analytes. Performance data obtained using a true homogeneous immunoassay format. A serum sample is added to a mast...U-M team: Genetic testing sheds light on degenerative eye disease
... careful screening of known disease genes leads to detection of pathogenic mutations in 25% to 90% of patients, an extraordinary accomplishment. It is to the patients advantage to have a molecular diagnosis on file, observes Ayyagari. When treatments begin to emerge for these complex genetic diseases, she ...New protein super-family discovered with critical functions for animal life
...members comprising the DANGER super-family escaped detection due to the high rates of mutations between family members, although a few family members had been detected previously and had been shown to control the differentiation of cells into organs in worms, fish, and mice. Deletion of these their DANGER gen......higan report development toward a "universal point detection system," a long sought three-in-one machine that ...and tested effectiveness of a SPAMS system for the detection of chemical and biological agents. The new research expands SPAMS' capabilities to include several k...