Impaired clearance of amyloid-beta causes vascular damage in Alzheimer's disease
...ally, the damage is so great that the blood vessel deteriorates beyond functional use and new vessels form to pick up the slack. The result is a multicentric dense-core plaque that associates with multiple vessels. These studies describe several animal models for further examining the pathogenesis and treatmen...UCLA scientists find male gene in brain area targeted by Parkinson's
...on of the brain called the substantia nigra, which deteriorates in Parkinson's disease. Parkinson's disease occurs when cells in the substantia nigra begin to malfunction and die. These brain cells produce a neurotransmitter called dopamine that communicates with the brain areas controlling movement and coordina...Male gene may explain higher incidence of Parkinsons in men
...on of the brain called the substantia nigra, which deteriorates in Parkinson's disease. Parkinson's disease develops when cells in the substantia nigra begin to malfunction and die, producing less dopamine. Dopamine, a chemical messenger, communicates with the brain to control movement and co-ordination. People w...How movement lubricates bone joints
...ilage at the ends of bones located at joints often deteriorates with aging, becoming increasingly roughened and eroded. Those joints become painful and progress to osteoarthritis. Surgeons can replace damaged and diseased joints with artificial joints, but they would like to be able to simply resurface patients e...DNA preserved in bones undergoing fossilization deteriorates up to 50 times faster when stored in a museum than when the bones are buried in the ground. This has just been shown by a paleogenetics team led by Eva-Maria Geigl (Institut Jacques Mono / CNRS Paris). This study, which was published in the Proceedi...