Genetically endowed worm may substitute for rodents in some toxicology testing
... internal organs. Toxicity screening during development evaluates how pre-selected amounts of chemicals af... "We know basically everything about the development of this particular organism through its entire lifespan," said NTP associate director Christopher Po...Academics work to help stressed-out cats
...concluded that this is a significant factor in the development FIC, and will be carrying out further studies to see how best this and other stress factors can be overcome." Dr Gunn-Moore recommends that cats that have FLUTD or FIC should be fed wet food, and encouraged to drink more fluid. This can be done, for...NSF gives 'teeth' to biomaterials research
...by Shalaby, president and director of research and development at Poly-Med, Inc. "By being engaged with Clemson f...ping meet the state's goals of increasing economic development by stimulating job growth in the emerging knowledge-based economy." Clemson University is committed ...Paratek Pharmaceuticals presents multiple sclerosis data at Society for Neuroscience annual meeting
...ibiotic use and will not further contribute to the development of antibiotic resistance. We believe that these highly active, orally available compounds will also prove to be well-tolerated for MS, and we are very proud of this accomplishment." ...UCSD biologists discover chemical important in guiding visual system development
...of electrical activity in the brain that guide the development of the visual system, a finding that may bring rew...ontaneous neural activity is needed for the normal development of the visual circuits in the brain, but how this activity is created is not well understood. UCSD ...Trojan-horse therapy blocks buildup of Alzheimer's plaque
...myloid protein aggregates that are critical to the development of the disease. The treatment involves dispatching a small molecule into the cell to enlist the aid of a larger "chaperone" protein to block the accumulation of the brain-clogging protein. The new "Trojan horse" technique overcomes a major challenge ...Red wine mist? Resveratrol shows potential effects against COPD, asthma, arthritis
... compounds may provide candidate molecules for the development of novel anti-inflammatory therapies." The current study "excluded a lot" of potential mechanisms of action, Donnelly said, but we "still don't know what its target receptor is as it binds like a protein, but acts like an estrogen," which it's not. "...Unique new platform offers European scientific community a common voice
...ions committed to the scientific and technological development of Europe. It provides a common forum to advocate independent scientific advice in European policy-making and stimulate the involvement of European scientists in the design and implementation of European science and technology policy. ISE now includ...Fly gut's 'sticky spot' for leishmaniasis parasite
... parasite survival represents a novel strategy for development of transmission-blocking vaccines against vector-borne diseases," Valenzuela and colleagues conclude. As Stephen Beverley and Deborah Dobson point out in an accompanying article, leishmaniasis is a common opportunistic infection in people with AIDS a...UCLA and Univ. of Utah researchers identify how a hormone regulates iron
... associated with too much hepcidin, Ganz adds that development of drugs to block hepcidin from binding to ferroportin might help release more iron into the body. Hemochromatosis is the most common genetic disease in the United States according to the Centers for Disease Control. One in 100-200 people have a dou...ASU gets grant to develop high speed DNA sequence reader
...illion going to several research teams to spur the development of innovative techniques to dramatically reduce the cost of DNA sequencing, a move aimed at broadening the application of genome information in medical research and health care. Goal of the three-year ASU grant is to develop a system that can read D...Research to explore revolutionary gene sequencing: Threading the molecular needle
...program, which the Institute says is aimed at "the development of breakthrough technologies that will enable a human-sized genome to be sequenced for $1,000 or less." As a scientist, however, Lindsay is careful in not claiming a breakthrough yet. "There is still a fair amount of harsh reality to deal...Scientists closing in on nerve proteins' contributions to memory and hearing loss
...ysical gap, and to other aspects of nervous system development and communication. Until recently, researchers gave little attention to Nrg-ICD, the interior portion of Nrg-1. But Jianxin Bao, Ph.D., research assistant professor of otolaryngology at Washington University and other scientists have begun amassin...Is the zebra fish leading us to new therapies?
...ific signal molecules. This is a major step in the development of new targeted forms of therapeutic angiogenesis....ue. Discovering these mechanisms would greatly aid development of new strategies for therapeutic angiogenesis. Not only must the growth of new blood vessels be sti...Research uncovers role of Apolipoprotein E in Alzheimer's disease
...id promoting activity of ApoE is essential for the development of both Alzheimer's pathology and cognitive decline," said Dr. Potter, professor of biochemistry and molecular biology who holds the Pfeiffer Endowed Chair in Alzheimer's Research at USF. "Thus, preventing ApoE from acting upon AB may prove to be an ...Human embryonic stem cells promising for replacement of blood supply
...tter defines the conditions under which blood cell development occurs, making the process easier to replicate. T...erests focus on hematopoietic and endothelial cell development from human and non-human primate embryonic stem cells. This research uses embryonic stem cells to un...Wistar study demonstrates heritability of non-genomic information
...and complex gene region responsible for the proper development of the basic body plan. These vital genes have been highly conserved in evolution, appearing in species as divergent as fruit flies, mice, and humans. Large genes often employ highly sophisticated regulatory mechanisms: a mandatory promoter that acti...Sick kids researchers unmask the potential of stem cells found in adult skin
...from this non-controversial source possess for the development of possible therapies for spinal cord injury and n...y embryonic cells that go out into the skin during development and then stay in reservoirs in hair follicles," said Dr. Freda Miller, the study's principal investi...Ethical paradigm: Relating embryonic stem cell use to organ donation
... embryonic cell use. Landry and Zucker detail the development of laws and practices surrounding the establishment of the definition of death for a fully developed human. At the point that brain function is irretrievably lost, even if other cells and organs remain alive, humans are considered organismically dea...Bristol scientists find key to unlock body's own cancer defence
... for many normal body functions. These include the development of the embryo and, in adults, wound healing, the development of the placenta in pregnancy and of muscles during physical training programmes. However, it is thou...