Tag: "development" at biology news
Army-funded effort examines androgen's role in bone loss
...cur in men with a 15 percent lifetime risk for the development
of fracture. Hip fractures tend to occur over the ...led hypogonadism are associated with osteoporosis development
in men. The disease also is a side effect of androgen deprivation therapy, a common treatment ...
Seeking better cancer treatments
...f androgens. With the structural data in hand, the development
of drugs that bind to the ligand binding domain of these receptors could become easier and lead to more effective treatments with fewer side effects," explains Professor Maria Armnia Carrondo of the Portuguese Instituto de Biologia Experimental e Tec...
IRCM scientist demonstrates basic active mechanism of immune-system cells
...ocytes to turn against the body. This leads to the development
of autoimmune diseases, which are characterized by...). Dr. Veillette's discovery paves the way for the development
of SLAM, SAP or FynT inhibitors, which could block excessive immune responses observed in patients w...
Concord grape juice increased HDL, lowered inflammatory marker linked to heart disease
...oluble CD40 ligand is thought to contribute to the development
of atherosclerosis and vascular inflammation. We have seen in previous studies of healthy subjects that drinking grape juice decreases superoxide production and inhibits platelet aggregation, yet its impact on the inflammatory properties of platelet...
Other highlights in the November 17 JNCI
...matoid arthritis and polymyositis, may promote the development
of EpsteinBarr virus (EBV)-positive lymphomas in p...ude that increased Pirh2 expression can affect the development
of lung tumors by reducing the activity of the p53 protein. Contact: Michelle Gailiun, Ohio State Un...
No getting around RET
...g plays a significant physiological role in either development
or regeneration. Enomoto first devised an elegant...certain parts of the central nervous system during development
and following injury, showed that Cis-only mice develop and regenerate structures that are both morp...
Study identifies molecular complex vital to creation of miRNAs
...gnificant roles in controlling gene expression and development
in many different settings. Now, a new study from researchers at The Wistar Institute identifies for the first time a molecular complex vital for the creation of miRNAs. This complex, dubbed the microprocessor complex, contains two proteins, one of w...
Abundance of myostatin in infected swine may result in reduced muscle mass
... four-week-long experiment, but it did lead to the development
of lesions that affected 8 percent of the total lu...infected pigs. Myostatin's role in muscle development
is becoming clear, Johnson said. Mice with the myostatin gene deleted become muscle-bound, and a de...
Researchers discover new way to boost grain crops' drought tolerance
...the University of California, Riverside report the development
of technology that increases the tolerance of grai...mined the role of ethylene during plant growth and development
since 1997. In the most recent study, conducted by UCR researchers and Pioneer Hi-Bred Internationa...
Sick Kids researchers confirm that cancer stem cells initiate and grow brain tumours
... maintain tumour growth. This discovery has led to development
of a mouse model for human brain tumours and opens the door for new therapeutic targets for the treatment of brain tumours. This research is reported in the November 18, 2004 issue of the scientific journal Nature . "Now that we have confirmed that ...
How running made us human
...ors so they could pursue predators long before the development
of bows, arrows, nets and spear-throwers reduced the need to run long distances. Another possibility is that early humans and their immediate ancestors ran to scavenge carcasses of dead animals maybe so they could beat hyenas or other scavengers t...
A 'repulsive' protein guides blood vessel development
...whether Sema3E and plexin-D1also contribute to the development
of connections in the spinal cord. Ginty and his colleagues plan to explore the role of the proteins in neural development, as well as whether the combination is involved in vascular patterning in the limbs....
Researchers discover defense mechanisms in some plants believed bred out by humans
...nts of the defense system to eventually arrest the development
of the foreign elements and kill them. So the beta-glucosidase-BGAF aggregate is involved in defense, Esen said, and behaves much like a football team that surrounds the ball carrier and keeps him from moving. The researchers' project is to und...
Six reporters reach the 'Pinnacle of Excellence'
...en, layers of information that affect inheritance, development
and disease." The story read like a thriller, with big ideas put forward for new avenues for science. Television Mark Davis wrote, directed and produced "Mars Dead or Alive," a drama that aired on WGBH/NOVA about the launch of the twin Mars Explor...
Down Syndrome protein reduces tumor growth
...erapeutic gain in non-Down syndrome patients. "The development
of methods to overexpress DSCR-1 in the endothelium would provide a novel strategy for reducing blood vessel formation and thus tumor growth, and for dampening endothelial cell dysfunction," says Dr. Minami....
Flies on crack
...caine in humans, potentially providing targets for development
of drugs to treat or prevent addiction. Hea...caine in humans, potentially providing targets for development
of drugs to treat or prevent addiction. "It's been established the some individuals may be predisp...
This is your fly's brain on drugs
...ine in humans, and potentially provide targets for development
of drugs to treat or prevent addiction. ...
Scientists achieve self-assembly of spider silk fiber in insect cells
... of Current Biology , opens the way to commercial development
of this spider fiber for numerous industrial applications. Silk has been in use by mankind for thousands of years. However, unlike silkworms, spiders are territorial in nature and thus not subject to domestication and commercial growth in quantitie...
HIV research project scoops innovation prize
...raction between human proteins and viruses and the development
of novel anti-infective compounds that could become the next generation of HIV-beating drugs as well as possible treatments for other viruses, such as herpes and hepatitis. "The compounds work by stopping the virus before it attaches itself to the ce...
How the battle of Waterloo could help doctors fight death from multiple organ failure
...energy expenditure seems to play a key role in the development
of sepsis-induced multiple organ failure. We think that some septic patients become deficient in leptin and this leads to energy failure and subsequent organ dysfunction. Exploring the relationship between leptin, body energy regulation and the sever...
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