NIH funds first nationaL SNP genotyping center at Broad Institute
...humans, may contribute to complex diseases such as diabetes and hypertension. "The tremendous potential of genetic research makes it critical that we develop this central resource so investigators around the country can access high capacity genotyping with the additional benefits of economies of scale, qualit...Is Interleukin-6 the 'holy grail' of exercise mediation?
...eating such metabolic disorders as obesity, type 2 diabetes and atherosclerosis. Many roles and sources promp...s, smokers and patients with non-insulin-dependent diabetes mellitus but there's no evidence that either is actually the source of these problems. Indeed, it's ...New genetic tools provide clues to the effects of exercise and diet on obesity, diabetes
...or the progression of NIDDM (non-insulin dependent diabetes mellitus, or type-2 diabetes) are sorely needed, as are quantitative endpoints for exercise and diet interventions," according to Dustin S. Hittel of the Research Center for Genetic Medicine at Children's National Medical Center (CNMC), Washington, D...Research into the sense of touch in worms wins Eppendorf/Science Prize
...d reduced touch sensation is common in people with diabetes and is a leading factor in lower-extremity amputation. However, scientists know very little about the molecular basis of touch, mainly because studying the sensory nerves that detect touch are deeply embedded under the skin, making it more difficult ...NHGRI seeks next generation of sequencing technologies
...udies to identify genes that contribute to cancer, diabetes and other common diseases. Ultimately, NHGRI's vision is to cut the cost of whole-genome sequencing to $1,000 or less, which would enable the sequencing of individual genomes as part of medical care. The ability to sequence each person's genome cost-...Diabetes hikes risk for liver, pancreatic cancers
SEATTLE--People with diabetes mellitus have three to four times the risk of deve...rmine whether those reporting a prior diagnosis of diabetes were more likely to have cancer. "Among those who reported being diabetic, there was a three-fold ...Gene linked to greater risk of heart disease in type 2 diabetes
...in a gene that help explain why people with type 2 diabetes are at much greater risk for coronary artery disea...e now have potential gene markers to help identify diabetes patients at increased risk for heart disease," said Alessandro Doria, M.D., Ph.D., Investigator in J...Lag-3 gene dampens immune responses by controlling regulatory T-cell function
...estructive effects of autoimmune diseases, such as diabetes type 1, which occurs when effector T cells mount an attack on the cells of the pancreas that produce insulin," Vignali said. However, regulatory T cells can also block the beneficial activity of anti-tumor effector cells. This braking a...Are yeast cells bringing us a step closer in treating obesity?
...s for the treatment of metabolic disorders such as diabetes and obesity. Detecting sugars in the cell Every living thing is composed of cells, which communicate with each other and the external world by means of receptor proteins on the cell membrane. These proteins receive signals from outside the cell by ...Study at Joslin shows ease of introducing technology to kids with diabetes
... game played on a wireless hand-held device do for diabetes management? A lot, according to a pilot study led ...erapeutics, found that youth ages 8-18 with type 1 diabetes were more apt to monitor their blood glucose levels more often when engaged in a game called DiaBetN...Gene therapy approach reverses diabetic neuropathy in animal model, Pitt study finds
... San Diego. More than two thirds of patients with diabetes develop neuropathy, which generally affects the se...om damage. In their study, the researchers induced diabetes in mice, which resulted in the development of peripheral neuropathy within six weeks. Once neuropath...ASU gets grant to develop high speed DNA sequence reader
...udies to identify genes that contribute to cancer, diabetes and other common diseases. The ASU team is utilizing part of the machinery of a human cell, which can read out the entire genome and make an exact complimentary copy of human DNA in about 24 hours. The team plans to use the DNA polymerase enzyme, wh...Diabetic damage to eyes, heart, nerves, kidneys may be explained by controversial theory
... Oct. 28, 2004 -- A controversial theory about how diabetes causes extensive tissue damage will appear in the ...heir study. "The metabolic imbalances caused by diabetes are quite complex, and that has made it very difficult to gain acceptance or even consideration of o...Fat buildup found in hearts of obese or diabetic heart failure patients
...egtmeyer said. "We also report in this paper that diabetes and obesity appear to cause metabolic irregulariti...tissue. Earlier research by Taegtmeyer showed that diabetes causes toxic levels of lipids and glucose to build up in the heart....Diabetes drug works by enhancing fat cell energy production
...rs to be central to this process. Drugs for type 2 diabetes that enhance sensitivity to insulin, such as rosiglitazone, work through mechanisms that involve fat. Cell culture work has indicated that rosiglitazone alters the mitochondria of fat cells, both in their structural features and in the types of prote...JCI table of contents November 1, 2004
...rs to be central to this process. Drugs for type 2 diabetes that enhance sensitivity to insulin, such as rosig...antigen can accelerate but not initiate autoimmune diabetes AUTHOR CONTACT: Matthias G. von Herrath La Jolla Institute for Allergy and Immunology, 10355 Science...Joslin Diabetes Center awards 1st Mary K. Iacocca Faculty Fellowship
...o Joslin to study broad areas of type 1 and type 2 diabetes and related complications. "With this new facul...neering to introduce new ideas and technologies to diabetes research," said George L. King, M.D., Director of Research at Joslin Diabetes Center, Professor of M...Cranfield collaborator receives multi million dollar financing
Cranfield University has been at the forefront of diabetes diagnostics for over twenty years and created the ...es the ease of use and convenience for people with diabetes but it also significantly reduces the pain of a procedure that millions of diabetics go through mult...UO study is first to link histamine receptors to heat stress
...es: the elderly and people with conditions such as diabetes and heart disease. The award-winning University of Oregon doctoral degree student's research is the first to identify histamine receptors as contributing to increased blood flow during heat stress. Skin blood flow is a key factor in compensating for ......g better biomarkers to predict who will get type 1 diabetes is one aim of Medical College of Georgia researche..., we want to identify biomarkers to predict type 1 diabetes using different approaches," says Dr. Jin-Xiong She, director of the MCG Center for Biotechnology an...