NIH grants $11 million to Brown University for cancer research
...ng and brain development as well as heart disease, diabetes and addiction. Brown was among the first universities to establish a COBRE, which are led by senior scientists who direct multidisciplinary efforts that focus on a theme, such as neuroscience or immunology. Training young researchers and creating cor...Antibody to a naturally-occurring sugar chain in colon inhibits inflammatory bowel disease
... the pathology of inflammation, as well as cancer, diabetes and Alzheimer's disease. They are also determining the exact molecular structure of the tweaked sugar chain, and will determine what other molecules and receptors may interact with it. Eventually, the researchers hope that they will have enough promi...Vanadium appears to play role in speeding recovery from infections
...w recovery might be encouraged and why people with diabetes tend to have lingering behavioral symptoms such as fatigue and apathy long after many infections end. Their latest research found that mice given vanadium -- in its typical vanadyl sulfate form -- before exposure to a pathogen sped recovery in both ...Gene makes muscles in the obese store more fat
...of obesity, and may contribute to problems such as diabetes and cardiovascular disease. The researchers discov...n. This excess fat storage may be linked to type 2 diabetes because skeletal muscle muscle attached to bone helps regulate sugar metabolism. When the muscle ...Muscle of obese 'programmed' to amass fat, genetic study finds
...uke University Medical Center. "Obesity and type 2 diabetes are strongly associated with abnormal lipid metabolism and the accumulation of fat droplets in muscle, but the underlying causes of these perturbations have been unknown," Muoio said. "We've now shown that SCD1 is at least a very important contributo...Electrical engineer works on personalizing medical treatment
...diet, environment, and alcohol consumption. Type 2 diabetes requires a systems approach, as it is caused almost entirely by multiple social factors, including diet and lack of exercise." Wang, based at Virginia Tech's Northern Virginia campus, also serves as an adjunct professor of radiology at Johns Hopkins ...Low blood glucose levels may complicate gastric bypass surgery, study shows
...stric bypass patients have what many of those with diabetes lack ample insulin and perhaps an understanding of this phenomenon could be harnessed to help those with diabetes. "If we can understand what processes are responsible for too much insulin production and too many islet cells in these patients, we ...UC Davis ophthalmologist to examine ancient Chilean mummy eyes
...y suggests any so-called modern day diseases, like diabetes or high blood pressure." It all began when Huck Holz, chief resident in the Department of Ophthalmology and Vision Science, read an article about the founder of modern paleopathology, Arthur Aufderheide, in the May 16 issue of the New Yorker magazine...JCI table of contents November, 2005
...C DISEASE Fattening up the targets for obesity and diabetes treatment Gs-alpha is a G protein alpha-subunit r...in liver may be a potential therapeutic target for diabetes and obesity. TITLE: Increased glucose tolerance and reduced adipocity in the absence of fasting hy...Studies on human genome variation provide insight into disease
... of improving diagnosis of common diseases such as diabetes and heart disease," says Cardon, "but the genome is tricky; it won't reveal its secrets easily. The real disease-causing culprits can have many silent partners. We need to know the relationships of all these partners to focus on real disease mutati...Nine minority physiology grad students each get $18,000 Porter Fellowship from APS
...ms studies zinc and its role in the development of diabetes mellitus at the level of the pancreatic -cell. Hi...ulin. Yet a common characteristic of all forms of diabetes mellitus is low zinc concentrations in the blood. This lack of zinc may be a factor leading to the ...Non-drug hypertension treatment device effectively reduces blood pressure in hypertensive diabetics
...nt of the 10 million Americans suffering from both diabetes and hypertension do not reach goal blood pressure ...re (p<0.005). "This is fantastic news for the diabetes community and for InterCure" said Erez Gavish, President & CEO of InterCure, the developer of RESPeR...Genetic prediction of Type 2 diabetes
...st two "diabetes genes" predict the risk of Type 2 diabetes (T2D) when combined with lifestyle factors, in the...ndidate genes for T2D for their ability to predict diabetes in 2293 people without diabetes in the Botnia prospective study in Western Finland from 1990 to 2002...Success tastes sweet for scientists
...es like sugar and could help control diseases like diabetes and obesity may be closer to reality thanks to res...low-calorie products to help control diseases like diabetes and obesity."...Why children of parents with type 2 diabetes are at risk themselves
...insulin-resistant offspring of parents with type 2 diabetes have reduced mitochondrial function. But the prec...ction in relation to insulin resistance and type 2 diabetes was not clear. In a paper appearing online on November 10 in advance of print publication of the Dec...JCI table of contents December, 2005
...=25371 METABOLIC DISEASE Reversing obesity and diabetes works when leptin signaling is on the brain Leptin is a hormone derived from fat cells, and defects in leptin signaling leads to obesity, overeating, and decreased energy output. Leptin signals through the leptin receptor, LEPR. In a paper appea...On World Diabetes Day, Joslin President warns of explosion in diabetes and its complications
...g 14 percent increase in the number of people with diabetes in the U.S. in the past two years alone, Joslin Di...onald Kahn, M.D., warns of a coming "explosion" in diabetes and its complications unless action is taken to curb the mushrooming incidence of type 2 diabetes. ...Sperm stem cells closer to being like embryonic stem cells
...eir potential use in humans to treat diseases like diabetes and Parkinson's is controversial because currently the only source of such cells for research is human embryos or mouse cells. Recently another research team published results showing that mouse male germ stem cells could be made to exhibit pluripote...Other highlights in the November 16 JNCI
... of Colorectal Cancer, Meta-Analysis Finds Having diabetes is associated with an increased risk of colorectal...a new meta-analysis. Most, but not all, studies of diabetes and colorectal cancer risk have found a positive association between the conditions. The findings ha...Leading researchers from Israel and Southern California to present stem cell symposium
...eas -- research that may impact such diseases as diabetes and cystic fibrosis. "Immune Cells and Adult Stem Cells Interact Synergistically to Renew Brain Cells and Rehabilitate Cognitive Functions in Dementias and Other Neurodegenerative Conditions," presented by Michal Schwartz, Ph.D., professor of Neuro...